The significance of circulating vascular endothelial growth factor (VEGF) protein in gastric cancer

Cancer Letters

Volumn 192, Issue 2, 2003, Pages 215-225

  Ohta, Manabu ^a   Konno, Hiroyuki ^a   Tanaka, Tatsuo ^a   Baba, Megumi ^a   Kamiya, Kinji ^a   Syouji, Tuyoshi ^a   Kondoh, Kenji ^a   Watanabe, Masaya ^a   Terada, Hirofumi ^a   Nakamura, Satoshi ^a  

^a HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Gastric cancer; Lymph nodes; Vascular endothelial growth factor

Indexed keywords

TUMOR MARKER; VASCULOTROPIN;

ADULT; ADVANCED CANCER; AGED; ARTICLE; CANCER STAGING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE MARKER; FEMALE; HUMAN; LYMPH NODE METASTASIS; MALE; METASTASIS; PLASMA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RELIABILITY; SERUM; STOMACH CANCER; TUMOR VOLUME; VENOUS BLOOD;

EID: 0037474752     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/0304-3835(02)00681-X     Document Type: Article

References (48)

1. Folkman J., Shing Y. Angiogenesis. J. Biol. Chem. 267:1992;10931-10934.
2. Ellis L.M., Fidler I.J. Angiogenesis and metastasis. Eur. J. Cancer. 32A:1996;2451-2460.
3. Takahashi Y., Kitadai Y., Bucana C.D., Cleary K.R., Ellis L. Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res. 55:1995;3964-3968.
4. Hanahan D., Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell. 86:1996;353-364.
5. Yancopoulos G.D., Davis S., Gale N.W., Rudge J.S., Wiegand S.J., Holash J. Vascular-specific growth factors and blood vessel formation. Nature. 407:2000;242-248.
6. Toi M., Hoshina S., Takayanagi T., Tominaga T. Association of vascular endothelial growth factor expression with tumor angiogenesis and with early relapse in primary breast cancer. Jpn. J. Cancer Res. 85:1994;1045-1049.
7. Dvorak H.F., Brown L.F., Detmar M., Dvorak A.M. Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. Am. J. Pathol. 146:1995;1029-1039.
8. Pepper M.S., Ferrara N., Orci L., Montesano R. Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem. Biophys. Res. Commun. 181:1991;902-906.
9. Unemori E.N., Ferrara N., Bauer E.A., Amento E.P. Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells. J. Cell Physiol. 153:1992;557-562.
10. Shaheen R.M., Davis D.W., Liu W., Zebrowski B.K., Wilson M.R., Bucana C.D., McConkey D.J., McMahon G., Ellis L.M. Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis. Cancer Res. 59:1999;5412-5416.
11. Gerber H.P., McMurtrey A., Kowalski J., Yan M., Keyt B.A., Dixit V., Ferrara N. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J. Biol. Chem. 273:1998;30336-30346.
12. Lissoni P., Malugani F., Bonfanti A., Bucovec R., Secondino S., Brivio F., Ferrari-Bravo A., Ferrante R., Vigore L., Rovelli F., Mandala M., Viviani S., Fumagalli L., Gardani G.S. Abnormally enhanced blood concentrations of vascular endothelial growth factor (VEGF) in metastatic cancer patients and their relation to circulating dendritic cells, IL-12 and endothelin-1. J. Biol. Regul. Homeost. Agents. 15:2001;140-144.
13. Brown L.F., Berse B., Jackman R.W., Tognazzi K., Manseau E.J., Senger D.R., Dvorak H.F. Expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in adenocarcinomas of the gastrointestinal tract. Cancer Res. 53:1993;4727-4735.
14. Brown L.F., Berse B., Jackman R.W., Tognazzi K., Manseau E.J., Dvorak H.F., Senger D.R. Increased expression of vascular permeability factor (vascular endothelial growth factor) and its receptors in kidney and bladder carcinomas. Am. J. Pathol. 143:1993;1255-1262.
15. Olson T.A., Mohanraj D., Carson L.F., Ramakrishnan S. Vascular permeability factor gene expression in normal and neoplastic human ovaries. Cancer Res. 54:1994;276-280.
16. Maeda K., Chung Y.S., Ogawa Y., Takatsuka S., Kang S.M., Ogawa M., Sawada T., Sowa M. Prognostic value of vascular endothelial growth factor expression in gastric carcinoma. Cancer. 77:1996;858-863.
17. Tanigawa N., Amaya H., Matsumura M., Shimomatsuya T., Horiuchi T., Muraoka R., Iki M. Extent of tumor vascularization correlates with prognosis and hematogenous metastasis in gastric carcinomas. Cancer Res. 1996;562671-562676.
18. Baba M., Konno H., Maruo Y., Tanaka T., Kanai T., Matsumoto K., Matsuura M., Nishino N., Maruyama K., Nakamura S., Baba S. Relationship of p53 and vascular endothelial growth factor expression of clinicopathological factors in human scirrhous gastric cancer. Eur. Surg. Res. 30:1998;130-137.
19. Konno H., Baba M., Tanaka T., Kamiya K., Ota M., Oba K., Shoji A., Kaneko T., Nakamura S. Overexpression of vascular endothelial growth factor is responsible for the hematogenous recurrence of early-stage gastric carcinoma. Eur. Surg. Res. 32:2000;177-181.
20. Yamamoto Y., Toi M., Kondo S., Matsumoto T., Suzuki H., Kitamura M., Turuta K., Taniguchi T., Okamoto A., Mori T., Yoshida M., Ikeda T., Tominaga K. Concentrations of vascular endothelial growth factor in sera of normal controls and cancer patients. Clin. Cancer Res. 2:1996;821-826.
21. Salven P., Ruotsalainen T., Mattson K., Joensuu H. High pre-treatment serum level of vascular endothelial growth factor (VEGF) is associated with poor outcome in small-cell lung cancer. Int. J. Cancer. 79:1998;144-146.
22. Chin K.F., Greenman J., Gardiner E., Kumar H., Topping K., Monson J. Pre-operative serum vascular endothelial growth factor can select patients for adjuvant treatment after curative resection in colorectal cancer. Br. J. Cancer. 83:2000;1425-1431.
23. Fujisaki K., Mitsuyama K., Toyonaga A., Matsuo K. Circulating vascular endothelial growth factor in patients with colorectal cancer. Am. J. Gastroenterol. 93:1998;249-252.
24. Harish K., Kamal H., Perter W.R.L., Graeme S., Duthie A., lastair W.M., John G., Michael J.K., John R.T.M. Preoperative serum vascular endothelial growth factor can predict stage in colorectal cancer. Clin. Cancer Res. 4:1998;1279-1285.
25. Dirix L.Y., Vermeulen P.B., Pawinski A., Prove A., Benoy I., De Pooter C., Martin M., Van Oosterom A.T. Elevated levels of the angiogenic cytokines basic fibroblast growth factor and vascular endothelial growth factor in sera of cancer patients. Br. J. Cancer. 76:1997;238-243.
26. Dirix L.Y., Vermeulen P.B., Hubens G., Benoy I., Martin M., De Pooter C., Van Oosterom A.T. Serum basic fibroblast growth factor and vascular endothelial growth factor and tumour growth kinetics in advanced colorectal cancer. Ann. Oncol. 7:1996;843-848.
27. Feldman A.L., Tamarkin L., Paciotti G.F., Simpson B.W., Linehan W.M., Yang J.C., Fogler W.E., Turner E.M., Alexander H.R.J., Libutti S.K. Serum endostatin levels are elevated and correlate with serum vascular endothelial growth factor levels in patients with stage IV clear cell renal cancer. Clin. Cancer Res. 6:2000;4628-4634.
28. Yamamoto S., Konishi I., Mandai M., Kuroda H., Komatsu T., Nanbu K., Sakahara H., Mori T. Expression of vascular endothelial growth factor (VEGF) in epithelial ovarian neoplasms: correlation with clinicopathology and patient survival, and analysis of serum. Br. J. Cancer. 76:1997;1221-1227.
29. Tempfer C., Obermair A., Hefler L., Haeusler G., Gitsch G., Kainz C. Vascular endothelial growth factor serum concentrations in ovarian cancer. Obstet. Gynecol. 92:1998;360-363.
30. Poon R.T., Ng I.O., Lau C., Zhu L.X., Yu W.C., Lo C.M., Fan S.T., Wong J. Serum vascular endothelial growth factor predicts venous invasion in hepatocellular carcinoma: a prospective study. Ann. Surg. 233:2001;227-235.
31. Shimada Y., Takeda S.I., Nabeya H., Okazumi Y., Matsubara H., Funami Y., Hayashi S., Gunji T., Kobayashi T. Clinical significance of serum vascular endothelial growth factor in esophageal squamous cell carcinoma. Cancer. 92:2001;663-669.
32. McDonnell C.O., Harmey J.H., Bouchier-Hayes D.J., Walsh T.N. Effect of multimodality therapy on circulating vascular endothelial growth factor levels in patients with oesophageal cancer. Br. J. Surg. 88:2001;1105-1109.
33. C.N. Qian, C.Q. Zhang, X. Guo, M.H. Hong, S.M. Cao, W.Y. Mai, H.Q. Min, H. Y.X. Zeng, Elevation of serum vascular endothelial growth factor in male patients with metastatic nasopharyngeal carcinoma, Cancer 88 (2000) 255-261.
34. Kitamura M., Toi M., Arai K., Iwasaki Y., Suzuki H., Matsuo K. Concentrations of vascular endothelial growth factor in the sera of gastric cancer patients. Oncol. Rep. 5:1998;1419-1424.
35. Yoshikawa T., Tsuburaya A., Kobayashi O., Sairenji M., Motohashi H., Yanoma S., Noguchi Y. Plasma concentrations of VEGF and bFGF in patients with gastric carcinoma. Cancer Lett. 152:2000;7-12.
36. Hyodo I., Doi T., Endo H., Hosokawa Y., Nishikawa Y., Tanimizu M., Jinno K., Kotani Y. Clinical significance of plasma vascular endothelial growth factor in gastrointestinal cancer. Eur. J. Cancer. 34:1998;2041-2045.
37. Tamura M., Ohta Y., Kajita T., Kimura K., Go T., Oda M., Nakamura H., Watanabe G. Plasma VEGF concentration can predict the tumor angiogenic capacity in non-small cell lung cancer. Oncol. Rep. 8:2001;1097-1102.
38. Davies M.M., Jonas S.K., Kaur S., Allen-Mersh T.G. Plasma vascular endothelial but not fibroblast growth factor levels correlate with colorectal liver metastasis vascularity and volume. Br. J. Cancer. 82:2000;1004-1008.
39. Banks R.E., Forbes M.A., Kinsey S.E., Stanley A., Ingham E., Walters C., Selby P.J. Release of the angiogenic cytokine vascular endothelial growth factor (VEGF) from platelets: significance for VEGF measurements and cancer biology. Br. J. Cancer. 77:1998;956-964.
40. George M.L., Eccles S.A., Tutton M.G., Aburafi A.M., Swift R.I. Correlation of plasma and serum vascular endothelial growth factor levels with platelet count in colorectal cancer: clinical evidence of platelet scavenging? Clin. Cancer Res. 6:2000;3147-3152.
41. Konno H., Abe J., Kaneko T., Baba M., Shoji A., Sunayama K., Kamiya K., Tanaka T., Suzuki S., Nakamura S., Urano T. Urokinase receptor and vascular endothelial growth factor are synergistically associated with the liver metastasis of colorectal cancer. Jpn. J. Cancer Res. 92:2001;516-523.
42. Verheul H.M., Hoekman K., Luykx-De Bakker S., Eekman C.A., Folman C.C., Broxterman H.J., Pinedo H.M. Platelet: transporter of vascular endothelial growth factor. Clin. Cancer Res. 3:1997;2187-2190.
43. Vermeulen P.B., Salven P., Benoy I., Gasparini G., Dirix L.Y. Blood platelets and serum VEGF in cancer patients. Br. J. Cancer. 79:1999;370-373.
44. E. Gunsilius, J. Tschmelitsch, A.L. Petzer, Correspondence re: M.L. George [correction of H.L. George] et al., Correlation of plasma and serum vascular endothelial growth factor levels with platelet count in colorectal cancer: clinical evidence of platelet scavenging? Clin. Cancer Res. 6: 3147-3152, 2000, Clin Cancer Res. 7 (2001) 443-444.
45. Gunsilius E., Petzer A., Stockhammer G., Nussbaumer W., Schumacher P., Clausen J., Gastl G. Thrombocytes are the major source for soluble vascular endothelial growth factor in peripheral blood. Oncology. 58:2000;169-174.
46. Werther K., Christensen I.J., Nielsen H.J. Prognostic impact of matched preoperative plasma and serum VEGF in patients with primary colorectal carcinoma. Br. J. Cancer. 86:2002;417-423.
47. Haraguchi M., Komuta K., Akashi A., Matsuzaki S., Urui J., Kanematsu T. Elevated IL-8 levels in the drainage vein of resectable Dukes' C colorectal cancer indicate high risk for developing hepatic metastasis. Oncol. Rep. 9:2002;159-165.
48. Adams J., Carder P.J., Downey S., Forbes M.A., MacLennan K., Allgar V., Kaufman S., Hallam S., Bicknell R., Walker J.I., Cairnduff F., Selby P.J., Perren T.J., Lansdown M., Banks R.E. Vascular endothelial growth factor (VEGF) in breast cancer: comparison of plasma, serum, and tissue VEGF and microvessel density and effects of tamoxifen. Cancer Res. 60:2000;2898-2905.