Unexpected down-regulation of the hIK1 Ca2+-activated K+ channel by its opener 1-ethyl-2-benzimidazolinone in HaCat keratinocytes. Inverse effects on cell growth and proliferation

Journal of Biological Chemistry

Volumn 278, Issue 5, 2003, Pages 3323-3330

  Koegel, Heidi ^a   Kaesler, Susanne ^b   Burgstahler, Ralf ^a   Werner, Sabine ^a,c   Alzheimer, Christian ^a,c  

^a UNIVERSITY OF MUNICH   (Germany)

^b ETH ZURICH   (Switzerland)

^c UNIVERSITY OF KIEL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CALCIUM; CELLS; ELECTROPHYSIOLOGY; FEEDBACK; MOLECULAR BIOLOGY; POTASSIUM; RNA;

CELL GROWTH;

BIOCHEMISTRY;

1 ETHYL 2 BENZIMIDAZOLINONE; BENZIMIDAZOLE DERIVATIVE; CALCIUM ACTIVATED POTASSIUM CHANNEL; CHLORZOXAZONE; MESSENGER RNA; UNCLASSIFIED DRUG; ZOXAZOLAMINE; 1-ETHYL-2-BENZIMIDAZOLINONE; CALCIUM CHANNEL STIMULATING AGENT; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; KCNN4 PROTEIN, HUMAN; POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CELL FATE; CELL GROWTH; CELL PROLIFERATION; CELL SIZE; CONDUCTANCE; ELECTROPHYSIOLOGY; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; KERATINOCYTE; MITOGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; CELL CULTURE; CELL DIVISION; CELL LINE; CELL MEMBRANE POTENTIAL; CHANNEL GATING; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; GLIOMA; KINETICS; PHYSIOLOGY;

ANIMALIA;

BENZIMIDAZOLES; CALCIUM CHANNEL AGONISTS; CELL DIVISION; CELL LINE; GENE EXPRESSION REGULATION; GLIOMA; HUMANS; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; ION CHANNEL GATING; KERATINOCYTES; KINETICS; MEMBRANE POTENTIALS; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0037474294     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208914200     Document Type: Article

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