The dynamics of T-cell fratricide: Application of a robust approach to mathematical modelling in immunology

Journal of Theoretical Biology

Volumn 222, Issue 1, 2003, Pages 53-69

  Asquith, Becca ^a   Bangham, Charles R M ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Fratricide: CTL; HTLV I; Immunology; Mathematical model; Robustness

Indexed keywords

NUMERICAL MODEL;

ARTICLE; CELL KILLING; CYTOTOXIC T LYMPHOCYTE; DYNAMICS; HUMAN T CELL LEUKEMIA VIRUS 1; HUMAN T CELL LEUKEMIA VIRUS INFECTION; IMMUNE SYSTEM; MATHEMATICAL MODEL; NONLINEAR SYSTEM; PREDICTION; PRIORITY JOURNAL; THEORETICAL MODEL; VIRUS LOAD;

HUMAN HERPESVIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN T-LYMPHOTROPIC VIRUS 1;

EID: 0037466387     PISSN: 00225193     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-5193(03)00013-4     Document Type: Article

References (52)

1. + T cells vary in differentiation phenotype in different persistent virus infections Nat. Med. 8(4):2002;379-385.
2. Asquith, B., 1999. Unpublished.
3. Asquith B., Hanon E., Taylor G., Bangham C.R. Is HTLV-I really silent? Philos. Trans. R. Soc. B. 355:2000;1013-1019.
4. Bachmann M.F., Barner M., Viola A., Kopf M. Distinct kinetics of cytokine production and cytolysis in effector and memory T cells after viral infection. Eur. J. Immunol. 29(1):1999;291-299.
5. + T cells with soluble HLA-A2/Tax11-19 tetramer complexes in patients with human T cell lymphotropic virus-associated myelopathy J. Immunol. 162(3):1999;1765-1771.
6. Brady J.N. Biology of HTLV-I: host cell interactions. Höllsberg P., Hafler D.A. Human T-Cell Lymphotropic Virus Types I. 1996;79-112 John Wiley & Sons, New York.
7. + T cells in acute infectious mononucleosis Nat. Med. 2(8):1996;906-911.
8. Cann A.J., Chen I.S.Y. Human T-cell leukemia virus types I and II. Fields B.N., Knipe D.M., Howley P.M., Chanock R.M., Melnick J.L., Monath T.P., Roizman B., Straus S.E. Virology. 3rd Edition:1996;Lippincott-Raven, Philadelphia.
9. Cavrois M., Leclercq I., Gout O., Gessain A., Wain-Hobson S., Wattel E. Persistent oligoclonal expansion of human T-cell leukemia virus type 1-infected circulating cells in patients with tropical spastic paraparesis/HTLV-1 associated myelopathy. Oncogene. 17(1):1998;77-82.
10. Cho I., Sugimoto M., Mita S., Tokunaga M., Imamura F., Ando M. In vivo proviral burden and viral RNA expression in T cell subsets of patients with human T lymphotropic virus type-1-associated myelopathy/tropical spastic paraparesis. Am. J. Trop. Med. Hyg. 53(4):1995;412-418.
11. Daenke S., Kermode A.G., Hall S.E., Taylor G., Weber J., Nightingale S., Bangham C.R. High activated and memory cytotoxic T-cell responses to HTLV-1 in healthy carriers and patients with tropical spastic paraparesis. Virology. 217(1):1996;139-146.
12. Daenke S., Parker C.E., Niewiesk S., Newsom-Davis J., Nightingale S., Bangham C.R.M. Spastic paraparesis in a patient carrying defective human T cell leukemia virus type I (HTLV-I) provirus sequences but lacking a humoral or cytotoxic T cell response to HTLV-I. J. Infect. Dis. 169(4):1994;941-943.
13. Gessain A., Gallo R., Franchini G. Low degree of human T-cell leukemia/lymphoma virus type 1 genetic drift in vivo as a means of monitoring viral transmission and movement of ancient human populations. J. Virol. 66(4):1992;2288-2295.
14. Greten T.F., Slansky J.E., Kubota R., Soldan S.S., Jaffee E.M., Leist T.P., Pardoll D.M., Jacobson S., Schneck J.P. Direct visualization of antigen-specific T cells: HTLV-1 Tax11-19 specific CD8(+) T cells are activated in peripheral blood and accumulate in cerebrospinal fluid from HAM/TSP patients. Proc. Natl. Acad. Sci. USA. 95(13):1998;7568-7573.
15. + T cells infected with HTLV-1 is prevented by cytotoxic T lymphocytes Blood. 95:2000;1386-1392.
16. + T Lymphocytes naturally infected with HTLV-1 Immunity. 13:2000;657-664.
17. Hellerstein M., Hanley M.B., Cesar D., Siler S., Papageorgopoulos C., Wieder E., Schmidt D., Hoh R., Neese R., Macallan D., Deeks S., McCune J.M. Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans. Nat. Med. 5(1):1999;83-89.
18. Höllsberg P. Mechanisms of T-cell activation by human T-cell lymphotropic virus type I. Microbiol. Mol. Biol. Rev. 63(2):1999;308-333.
19. Jeffery K.J., Usuku K., Hall S.E., Matsumoto W., Taylor G.P., Procter J., Bunce M., Ogg G.S., Welsh K.I., Weber J.N., Lloyd A.L., Nowak M.A., Nagai M., Kodama D., Izumo S., Osame M., Bangham C.R. HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy. Proc. Natl. Acad. Sci. USA. 96(7):1999;3848-3853.
20. Koyanagi Y., Itoyama Y., Nakamura N., Takamatsu K., Kira J., Iwamasa T., Goto I., Yamamoto N. In vivo infection of human T-cell leukemia virus type I in non-T cells. Virology. 196(1):1993;25-33.
21. + memory T cells J. Exp. Med. 186(6):1997;859-865.
22. Lloyd, A., 1999. Unpublished communication.
23. Manns A., Miley W.J., Wilks R.J., Morgan O.S., Hanchard B., Wharfe G., Cranston B., Maloney E., Welles S.L., Blattner W.A., Waters D. Quantitative proviral DNA and antibody levels in the natural history of HTLV-I infection. J. Infect. Dis. 180(5):1999;1487-1493.
24. Mansky L.M. In vivo analysis of human T-cell leukemia virus type 1 reverse transcription accuracy. J. Virol. 74(20):2000;9525-9531.
25. Matsuzaki T., Nakagawa M., Nagai M., Usuku K., Higuchi I., Arimura K., Kubota H., Izumo S., Akiba S., Osame M. HTLV-I proviral load correlates with progression of motor disability in HAM/TSP. analysis of 239 HAM/TSP patients including 64 patients followed up for 10 years J. Neurovirol. 7:2001;228-234.
26. McLean A., Michie C. In vivo estimates of division and death rates of human T lymphocytes. Proc. Natl. Acad. Sci. USA. 92:1995;3707-3711.
27. O'Callaghan C.A., McMichael A.J. A new look at T cells. J. Exp. Med. 187(9):1998;1367-1371.
28. Michie C.A., McLean A., Alcock C., Beverley P.C. Lifespan of human lymphocyte subsets defined by CD45 isoforms. Nature. 360(6401):1992;264-265.
29. Mohri H., Bonhoeffer S., Monard S., Perelson A.S., Ho D.D. Rapid turnover of T lymphocytes in SIV-infected rhesus macaques. Science. 279(5354):1998;1223-1227.
30. Mongkolsapaya J., Jaye A., Callan M.F., Magnusen A.F., McMichael A.J., Whittle H.C. Antigen-specific expansion of cytotoxic T lymphocytes in acute measles virus infection. J. Virol. 73(1):1999;67-71.
31. Moritoyo, T., Tara, M., Hayakawa, H., Moritoyo, H., Sorimachi, M., Izumo, S., Osame, M., 2001. In situ visualization of HTLV-1 proviral DNA in cells from patients with ATL and HAM/TSP. Work presented 10th International Conference on Human Retrovirology.
32. Mueller N.E., Blattner W.A. HTLV. Evans A.S., Kaslow R. Viral Infections of Humans: Epidemiology and Control. 4th Edition:1997;Plenum, New York.
33. Murali-Krishna K., Altman J.D., Suresh M., Sourdive D., Zajac A., Ahmed R. In vivo dynamics of anti-viral CD8 T cell responses to different epitopes. An evaluation of bystander activation in primary and secondary responses to viral infection. Adv. Exp. Med. Biol. 452:1998;123-142.
34. Murali-Krishna K., Altman J.D., Suresh M., Sourdive D.J., Zajac A.J., Miller J.D., Slansky J., Ahmed R. Counting antigen-specific CD8 T cells. a reevaluation of bystander activation during viral infection Immunity. 8(2):1998;177-187.
35. Nagai M., Usuku K., Matsumoto W., Kodama D., Takenouchi N., Moritoyo T., Hashiguchi S., Ichinose M., Bangham C.R., Izumo S., Osame M. Analysis of HTLV-I proviral load in 202 HAM/TSP patients and 243 asymptomatic HTLV-I carriers. high proviral load strongly predisposes to HAM/TSP J. Neurovirol. 4:1998;586-593.
36. Nanan R., Rauch A., Kampgen E., Niewiesk S., Kreth H.W. A novel sensitive approach for frequency analysis of measles virus-specific memory T-lymphocytes in healthy adults with a childhood history of natural measles. J. Gen. Virol. 81(Part 5):2000;1313-1319.
37. Oehen S., Brduscha-Riem K. Differentiation of naive CTL to effector and memory CTL. correlation of effector function with phenotype and cell division J. Immunol. 161(10):1998;5338-5346.
38. + T cells during acute Epstein-Barr virus infection Blood. 97(3):2001;700-707.
39. Raftery M.J., Behrens C.K., Muller A., Krammer P.H., Walczak H., Schonrich G. Herpes simplex virus type 1 infection of activated cytotoxic T cells. induction of fratricide as a mechanism of viral immune evasion J. Exp. Med. 190(8):1999;1103-1114.
40. Richardson J.H., Edwards A.J., Cruickshank J.K., Rudge P., Dalgleish A.G. In vivo cellular tropism of human T-cell leukemia virus type 1. J. Virol. 64(11):1990;5682-5687.
41. + T cells Blood. 98(5):2001;1506-1511.
42. Sallusto F., Lenig D., Forster R., Lipp M., Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature. 401(6754):1999;708-712.
43. + T cells from patients with viral infections Biochem. Soc. Trans. 28(2):2000;255-258.
44. Sommerfelt M.A., Williams B.P., Clapham P.R., Solomon E., Goodfellow P.N., Weiss R.A. Human T cell leukemia viruses use a receptor determined by human chromosome 17. Science. 242(4885):1988;1557-1559.
45. Sutton R.E., Littman D.R. Broad host range of human T-cell leukemia virus type 1 demonstrated with an improved pseudotyping system. J. Virol. 70(10):1996;7322-7326.
46. Taylor G.P., Hall S.E., Navarrete S., Michie C.A., Davis R., Witkover A.D., Rossor M., Nowak M.A., Rudge P., Matutes E., Bangham C.R., Weber J.N. Effect of lamivudine on human T-cell leukemia virus type 1 (HTLV-1) DNA copy number, T-cell phenotype, and anti-tax cytotoxic T-cell frequency in patients with HTLV-1-associated myelopathy. J. Virol. 73(12):1999;10289-10295.
47. Taylor G.P., Tosswill J.H., Matutes E., Daenke S., Hall S., Bain B.J., Davis R., Thomas D., Rossor M., Bangham C.R., Weber J.N. Prospective study of HTLV-I infection in an initially asymptomatic cohort. J. Acquir. Immune. Defic. Syndr. 22(1):1999;92-100.
48. Van Parijs L., Biuckians A., Abbas A.K. Functional roles of Fas and Bcl-2-regulated apoptosis of T lymphocytes. J. Immunol. 160(5):1998;2065-2071.
49. Vella A.T., Dow S., Potter T.A., Kappler J., Marrack P. Cytokine-induced survival of activated T cells in vitro and in vivo. Proc. Natl. Acad. Sci. USA. 95(7):1998;3810-3815.
50. Wattel E., Cavrois M., Gessain A., Wain-Hobson S. Clonal Expansion of infected cells. a way of life for HTLV-1 J. Acquir. Immune. Defic. Syndr. 13(Suppl. 1):1996;S92-S99.
51. Wattel E., Vartanian J.P., Pannetier C., Wain-Hobson S. Clonal expansion of human T-cell leukemia virus type I-infected cells in asymptomatic and symptomatic carriers without malignancy. J. Virol. 69(5):1995;2863-2868.
52. Wucherpfennig K.W., Höllsberg P., Richardson J.H., Benjamin D., Hafler D.A. T-cell activation by autologous human T-cell leukemia virus type I-infected T-cell clones. Proc. Natl. Acad. Sci. USA. 89(6):1992;2110-2114.