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This situation is similar to the one we have recently observed in surface-confined imidazoles in gold nanoparticles where cooperativity has been found: Pasquato, L.; Rancan, F.; Scrimin, P.; Mancin, F.; Frigeri, C. Chem. Commun. 2000, 2253-2254. It is noteworthy that dendrimers carrying [Co(salen)] complexes on the surface exhibit significantly enhanced catalytic activity in the hydrolytic kinetic resolution of terminal epoxides: Breinbauer, R.; Jacobsen, E. N. Angew. Chem., Int. Ed. 2000, 39, 3604-3607.
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This situation is similar to the one we have recently observed in surface-confined imidazoles in gold nanoparticles where cooperativity has been found: Pasquato, L.; Rancan, F.; Scrimin, P.; Mancin, F.; Frigeri, C. Chem. Commun. 2000, 2253-2254. It is noteworthy that dendrimers carrying [Co(salen)] complexes on the surface exhibit significantly enhanced catalytic activity in the hydrolytic kinetic resolution of terminal epoxides: Breinbauer, R.; Jacobsen, E. N. Angew. Chem., Int. Ed. 2000, 39, 3604-3607.
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note
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A reviewer suggested that the peptide could interact with the hydrocarbon monolayer without binding to the Au surface. We have ruled out this possibility by showing that a peptide devoid of the thiolate function does not bind to MPC-C12 under identical conditions of the exchange experiment.
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35
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The formation of intramonolayer hydrogen bonds has been observed in MPCs protected with thiols containing amide moieties, and it depends on the distance of the amide from the nanoparticle core: Boal, A. K.; Rotello, V. M. Langmuir 2000, 16, 9527-9532.
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Boal, A.K.1
Rotello, V.M.2
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