Effects of changes in three catalytic residues on the relative stabilities of some of the intermediates and transition states in the citrate synthase reaction

Biochemistry

Volumn 37, Issue 27, 1998, Pages 9724-9737

  Kurz, Linda C ^a   Nakra, Tanuj ^a   Stein, Richard ^a   Plungkhen, Wanda ^a   Riley, Marian ^a   Hsu, Fong ^b   Drysdale, George R ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A; CITRATE SYNTHASE; CITRIC ACID; MUTANT PROTEIN;

ARTICLE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME STABILITY; ENZYME SUBUNIT; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SWINE;

ACETYL COENZYME A; ACYL COENZYME A; AMINO ACID SUBSTITUTION; ANIMALS; ARGININE; ASPARAGINE; BINDING SITES; CATALYSIS; CIRCULAR DICHROISM; CITRATE (SI)-SYNTHASE; CITRIC ACID; ENZYME STABILITY; GLUTAMINE; GLYCINE; HISTIDINE; HYDROLYSIS; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MUTAGENESIS, SITE-DIRECTED; OXALOACETATES; OXALOACETIC ACIDS; PROTONS; SOLVENTS; SUBSTRATE SPECIFICITY; SWINE;

SUS SCROFA;

EID: 0032493462     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi980325g     Document Type: Article

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