Preferential neurotrophic activity of fibroblast growth factor-20 for dopaminergic neurons through fibroblast growth factor receptor-1c

Journal of Neuroscience Research

Volumn 72, Issue 4, 2003, Pages 436-443

  Ohmachi, Shigeki ^a   Mikami, Tadahisa ^a   Konishi, Morichika ^a   Miyake, Ayumi ^a   Itoh, Nobuyuki ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Brain; Dopmaninergic neuron; FGF; FGF receptor; MAPK; Neurotrophic factor

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 3 [4 METHYL 2 (2 OXO 3 INDOLINYLMETHYLIDENYL) 3 PYRROLYL]PROPIONIC ACID; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 1 INHIBITOR; FIBROBLAST GROWTH FACTOR 20; FIBROBLAST GROWTH FACTOR RECEPTOR 1C; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; NEUROTROPHIC FACTOR; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DOPAMINERGIC NERVE CELL; IN SITU HYBRIDIZATION; MESENCEPHALON; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; RAT; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; DOPAMINE; ENZYME INHIBITORS; FIBROBLAST GROWTH FACTORS; FLAVONOIDS; IN SITU HYBRIDIZATION; MESENCEPHALON; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; PHOSPHORYLATION; PYRROLES; RATS; RATS, WISTAR; RECEPTOR PROTEIN-TYROSINE KINASES; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTORS, FIBROBLAST GROWTH FACTOR; RNA, MESSENGER; SIGNAL TRANSDUCTION;

EID: 0037447999     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10592     Document Type: Article

References (30)

1. Baloh RH, Tansey MG, Lampe PA, Fahrner TJ, Enomoto H, Simburger KS, Leitner ML, Araki T, Johnson EM Jr, Milbrandt J. 1998. Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex. Neuron 21:1291-1302.
2. Bhave SV, Ghoda L, Hoffman PL. 1999. Brain-derived neurotrophic factor mediates the anti-apoptotic effect of NMDA in cerebellar granule neurons: signal transduction cascades and site of ethanol action. J Neurosci 19:3277-3286.
3. Emoto N, Gonzalez AM, Walicke PA, Wada E, Simmons DM, Shimasaki S, Baird A. 1989. Basic fibroblast growth factor (FGF) in the central nervous system: identification of specific loci of basic FGF expression in the rat brain. Growth Factors 2:21-29.
4. Ernfors P, Wetmore C, Olson L, Persson H. 1990. Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family. Neuron 5:511-526.
5. Fallon JH, Loughlin SE. 1995. Substantia nigra. In: Paxinos G, editor. The rat nervous system, 2nd ed. San Diego: Academic Press. p 215-238.
6. Gerfen CR. 1989. Quantification of in situ hybridization histochemistry for analysis of brain function. In: Conn PM, editor. Methods in neurosciences. San Diego: Academic Press. p 79-97.
7. German DC, Manaye KF. 1993. Midbrain dopaminergic neurons (nuclei A8, A9, and A10): three-dimensional reconstruction in the rat. J Comp Neurol 331:297-309.
8. Hansen MR, Zha XM, Bok J, Green SH. 2001. Multiple distinct signal pathways, including an autocrine neurotrophic mechanism, contribute to the survival-promoting effect of depolarization on spiral ganglion neurons in vitro. J Neurosci 21:2256-2267.
9. Hyman C, Hofer M, Barde YA, Juhasz M, Yancopoulos GD, Squinto SP, Lindsay RM. 1991. BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra. Nature 350:230-232.
10. Hyman C, Juhasz M, Jackson C, Wright P, Ip NY, Lindsay RM. 1994. Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon. J Neurosci 14:335-347.
11. Ibi M, Sawada H, Nakanishi M, Kume T, Katsuki H, Kaneko S, Shimohama S, Akaike A. 2001. Protective effects of 1 alpha,25-(OH)(2)D(3) against the neurotoxicity of glutamate and reactive oxygen species in mesencephalic culture. Neuropharmacology 40:761-771.
12. Knusel B, Michel PP, Schwaber JS, Hefti F. 1990. Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor, basic fibroblast growth factor, epidermal growth factor, insulin and the insulin-like growth factors I and II. J Neurosci 10:558-570.
13. Konishi M, Mikami T, Yamasaki M, Miyake A, Itoh N. 2000. Fibroblast growth factor-16 is a growth factor for embryonic brown adipocytes. J Biol Chem 275:12119-12122.
14. Lin LF, Doherty DH, Lile JD, Bektesh S, Collins F. 1993. GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons. Science 260:1130-1132.
15. Matsuo A, Tooyama I, Isobe S, Oomura Y, Akiguchi I, Hanai K, Kimura J, Kimura H. 1994. Immunohistochemical localization in the rat brain of an epitope corresponding to the fibroblast growth factor receptor-1. Neuroscience 60:49-66.
16. Milbrandt J, de Sauvage FJ, Fahrner TJ, Baloh RH, Leitner ML, Tansey MG, Lampe PA, Heuckeroth RO, Kotzbauer PT, Simburger KS, Golden JP, Davies JA, Vejsada R, Kato AC, Hynes M, Sherman D, Nishimura M, Wang LC, Vandlen R, Moffat B, Klein RD, Poulsen K, Gray C, Garces A, Johnson EM Jr, et al. 1998. Persephin, a novel neurotrophic factor related to GDNF and neurturin. Neuron 20:245-253.
17. Miyake A, Hattori Y, Ohta M, Itoh N. 1996. Rat oligodendrocytes and astrocytes preferentially express fibroblast growth factor receptor-2 and -3 mRNAs. J Neurosci Res 45:534-541.
18. Mohammadi M, McMahon G, Sun L, Tang C, Hirth P, Yeh BK, Hubbard SR, Schlessinger J. 1997. Structures of the tyrosine kinase domain of fibroblast growth factor receptor in complex with inhibitors. Science 276:955-960.
19. Ohmachi S, Watanabe Y, Mikami T, Kusu N, Ibi T, Akaike A, Itoh N. 2000. FGF-20, a novel neurotrophic factor, preferentially expressed in the substantia nigra pars compacta of rat brain. Biochem Biophys Res Commun 277:355-360.
20. Ornitz DM, Xu J, Colvin JS, McEwen DG, MacArthur CA, Coulier F, Gao G, Goldfarb M. 1996. Receptor specificity of the fibroblast growth factor family. J Biol Chem 271:15292-15297.
21. Otto D, Unsicker K. 1990. FGF reverses chemical and morphological deficits in the nigrostriatal system of MPTP-treated mice. J Neurosci 10:1912-1921.
22. Pochon NA, Menoud A, Tseng JL, Zurn AD, Aebischer P. 1997. Neuronal GDNF expression in the adult rat nervous system identified by in situ hybridization. Eur J Neurosci 9:463-471.
23. Sawada H, Kawamura T, Shimohama S, Akaike A, Kimura J. 1996. Different mechanisms of glutamate-induced neuronal death between dopaminergic and non-dopaminergic neurons in rat mesencephalic culture. J Neurosci Res 43:503-510.
24. Skaper SD, Kee WJ, Facci L, Macdonald G, Doherty P, Walsh FS. 2000. The FGFR1 inhibitor PD 173074 selectively and potently antagonizes FGF-2 neurotrophic and neurotropic effects. J Neurochem 75:1520-1527.
25. Szebenyi G, Fallon JF. 1999. Fibroblast growth factors as multifunctional signaling factors [review]. Int Rev Cytol 185:45-106.
26. Walker DG, Terai K, Matsuo A, Beach TG, McGeer EG, McGeer PL. 1998. Immunohistochemical analyses of fibroblast growth factor receptor-1 in the human substantia nigra. Comparison between normal and Parkinson's disease cases. Brain Res 794:181-187.
27. Wert MM, Palfrey HC. 2000. Divergence in the anti-apoptotic signalling pathways used by nerve growth factor and basic fibroblast growth factor (bFGF) in PC12 cells: rescue by bFGF involves protein kinase C delta. Biochem J 352:175-182.
28. Woodward WR, Nishi R, Meshul CK, Williams TE, Coulombe M, Eckenstein FP. 1992. Nuclear and cytoplasmic localization of basic fibroblast growth factor in astrocytes and CA2 hippocampal neurons. J Neurosci 12:142-152.
29. Yamashita T, Konishi M, Miyake A, Inui K, Itoh N. 2002. Fibroblast growth factor (FGF)-23 inhibits renal phosphate reabsorption by activation of the mitogen-activated protein kinase pathway. J Biol Chem 277:28265-28270.
30. Yazaki N, Hosoi Y, Kawabata K, Miyake A, Minami M, Satoh M, Ohta M, Kawasaki T, Itoh N. 1994. Differential expression patterns of mRNAs for members of the fibroblast growth factor receptor family, FGFR-1FGFR-4, in rat brain. J Neurosci Res 37:445-452.