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Volumn 64, Issue 2, 1997, Pages 196-208

Methyl-group donors cannot prevent apoptotic death of rat hepatocytes induced by choline-deficiency

Author keywords

apoptosis; betaine; choline; methionine; phosphatidylcholine

Indexed keywords

ACETYLCHOLINE; CHOLINE; METHYL GROUP;

EID: 0031021449     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(199702)64:2<196::AID-JCB3>3.0.CO;2-S     Document Type: Article
Times cited : (47)

References (75)
  • 1
    • 0029985230 scopus 로고    scopus 로고
    • Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture
    • Albright CD, Lui R, Bethea TC, da Costa K-A, Salganik RI, Zeisel SH (1996): Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture. FASEB J 10:510-516.
    • (1996) FASEB J , vol.10 , pp. 510-516
    • Albright, C.D.1    Lui, R.2    Bethea, T.C.3    Da Costa, K.-A.4    Salganik, R.I.5    Zeisel, S.H.6
  • 2
    • 0022970777 scopus 로고
    • The effect of methotrexate on intracellular folate pools in human MCF-7 breast cancer cells. Evidence for direct inhibition of purine synthesis
    • Allegra CJ, Fine RL, Drake JC, Chabner BA (1986): The effect of methotrexate on intracellular folate pools in human MCF-7 breast cancer cells. Evidence for direct inhibition of purine synthesis. J Biol Chem 261:6478-6485.
    • (1986) J Biol Chem , vol.261 , pp. 6478-6485
    • Allegra, C.J.1    Fine, R.L.2    Drake, J.C.3    Chabner, B.A.4
  • 3
    • 0025049277 scopus 로고
    • Conjugated diene and trans fatty acids in a choline-devoid diet hepatocarcinogenic in the rat
    • Banni S, Evans RW, Salgo MG, Corongiu FP, Lombardi B (1990): Conjugated diene and trans fatty acids in a choline-devoid diet hepatocarcinogenic in the rat. Carcinogenesis 11:2047-2051.
    • (1990) Carcinogenesis , vol.11 , pp. 2047-2051
    • Banni, S.1    Evans, R.W.2    Salgo, M.G.3    Corongiu, F.P.4    Lombardi, B.5
  • 4
    • 33845261493 scopus 로고
    • A rapid method of total lipid extraction and purification
    • Bligh EG, Dyer WJ (1959): A rapid method of total lipid extraction and purification. Can J Biochem Physiol 37: 911-917.
    • (1959) Can J Biochem Physiol , vol.37 , pp. 911-917
    • Bligh, E.G.1    Dyer, W.J.2
  • 5
    • 0028987154 scopus 로고
    • Lysophosphatidyl-choline and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine inhibit the CDP-choline pathway of phosphatidylcholine synthesis at the CTP:phosphocholine cytidylyltransferase step
    • Boggs KP, Rock CO, Jackowski S (1995a): Lysophosphatidyl-choline and 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine inhibit the CDP-choline pathway of phosphatidylcholine synthesis at the CTP:phosphocholine cytidylyltransferase step. J Biol Chem 270:7757-7764.
    • (1995) J Biol Chem , vol.270 , pp. 7757-7764
    • Boggs, K.P.1    Rock, C.O.2    Jackowski, S.3
  • 6
    • 0029019501 scopus 로고
    • Lysophosphatidyl-choline attenuates the cytotoxic effects of the antineoplastic phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine
    • Boggs KP, Rock CO, Jackowski S (1995b): Lysophosphatidyl-choline attenuates the cytotoxic effects of the antineoplastic phospholipid 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine. J Biol Chem 270:11612-11618.
    • (1995) J Biol Chem , vol.270 , pp. 11612-11618
    • Boggs, K.P.1    Rock, C.O.2    Jackowski, S.3
  • 7
    • 0022141157 scopus 로고
    • The molecules of the cell membrane
    • Bretscher MS (1985): The molecules of the cell membrane. Sci Am 253:100-108.
    • (1985) Sci Am , vol.253 , pp. 100-108
    • Bretscher, M.S.1
  • 10
    • 0027418511 scopus 로고
    • Low plasma free choline is prevalent in patients receiving long term parenteral nutrition and is associated with hepatic aminotransferase abnormalities
    • Buchman AL, Moukarzel A, Jenden DJ, Roch M, Rice K, Ament ME (1993): Low plasma free choline is prevalent in patients receiving long term parenteral nutrition and is associated with hepatic aminotransferase abnormalities. Clin Nutr 12:33-37.
    • (1993) Clin Nutr , vol.12 , pp. 33-37
    • Buchman, A.L.1    Moukarzel, A.2    Jenden, D.J.3    Roch, M.4    Rice, K.5    Ament, M.E.6
  • 13
    • 0024306834 scopus 로고
    • Choline may be an essential nutrient in malnourished patients with cirrhosis
    • Chawla RK, Wolf DC, Kutner MH, Bonkovsky HL (1989): Choline may be an essential nutrient in malnourished patients with cirrhosis. Gastroenterology 97:1514-20.
    • (1989) Gastroenterology , vol.97 , pp. 1514-1520
    • Chawla, R.K.1    Wolf, D.C.2    Kutner, M.H.3    Bonkovsky, H.L.4
  • 14
    • 0028964976 scopus 로고
    • Dietary effects on DNA methylation: Do they account for the hepatocarcinogenic properties of lipotrope deficient diets?
    • Christman JK (1995a): Dietary effects on DNA methylation: Do they account for the hepatocarcinogenic properties of lipotrope deficient diets? Adv Exp Med Biol 369: 141-154.
    • (1995) Adv Exp Med Biol , vol.369 , pp. 141-154
    • Christman, J.K.1
  • 15
    • 0029072763 scopus 로고
    • Lipotrope deficiency and persistent changes in DNA methylation. Lipotrope deficiency and DNA methylation
    • Christman JK (1995b): Lipotrope deficiency and persistent changes in DNA methylation. Lipotrope deficiency and DNA methylation. Adv Exp Med Biol 375:97-106.
    • (1995) Adv Exp Med Biol , vol.375 , pp. 97-106
    • Christman, J.K.1
  • 16
    • 0030044041 scopus 로고    scopus 로고
    • Expression of phosphatidylethanolamine N-methyltransferase-2 is markedly enhanced in long term choline-deficient rats
    • Cui Z, Vance DE (1996): Expression of phosphatidylethanolamine N-methyltransferase-2 is markedly enhanced in long term choline-deficient rats. J Biol Chem 271:2839-2843.
    • (1996) J Biol Chem , vol.271 , pp. 2839-2843
    • Cui, Z.1    Vance, D.E.2
  • 17
    • 0027941817 scopus 로고
    • Suppression of rat hepatoma cell growth by expression of phosphatidylethanolamine N-methyltransferase-2
    • Cui Z, Houweling M, Vance DE (1994): Suppression of rat hepatoma cell growth by expression of phosphatidylethanolamine N-methyltransferase-2. J Biol Chem 269:24531-24533.
    • (1994) J Biol Chem , vol.269 , pp. 24531-24533
    • Cui, Z.1    Houweling, M.2    Vance, D.E.3
  • 18
    • 0027393046 scopus 로고
    • Accumulation of 1,2-sn-diradylglycerol with increased membrane-associated protein kinase C may be the mechanism for spontaneous hepatocarcinogenesis in choline deficient rats
    • da Costa K, Cochary EF, Blusztajn JK, Garner SC, Zeisel SH (1993): Accumulation of 1,2-sn-diradylglycerol with increased membrane-associated protein kinase C may be the mechanism for spontaneous hepatocarcinogenesis in choline deficient rats. J Biol Chem 268:2100-2105.
    • (1993) J Biol Chem , vol.268 , pp. 2100-2105
    • Costa, K.1    Cochary, E.F.2    Blusztajn, J.K.3    Garner, S.C.4    Zeisel, S.H.5
  • 19
    • 0028798679 scopus 로고
    • Effects of prolonged (1 year) choline deficiency and subsequent refeeding of choline on 1,2,-sn-diradylglycerol, fatty acids and protein kinase C in rat liver
    • da Costa K-A, Garner SC, Chang J, Zeisel SH (1995): Effects of prolonged (1 year) choline deficiency and subsequent refeeding of choline on 1,2,-sn-diradylglycerol, fatty acids and protein kinase C in rat liver. Carcinogenesis 16:327-334.
    • (1995) Carcinogenesis , vol.16 , pp. 327-334
    • Costa, K.-A.1    Garner, S.C.2    Chang, J.3    Zeisel, S.H.4
  • 20
    • 0023738916 scopus 로고
    • A quick and simple method for the quantitation of lactate dehydrogenase release in measurement of cellular cytotoxicity and tumor necrosis factor (TNF) activity
    • Decker T, Lohmann-Matthes M-L (1988): A quick and simple method for the quantitation of lactate dehydrogenase release in measurement of cellular cytotoxicity and tumor necrosis factor (TNF) activity. J Immunol Methods 15:61-69.
    • (1988) J Immunol Methods , vol.15 , pp. 61-69
    • Decker, T.1    Lohmann-Matthes, M.-L.2
  • 21
    • 0025870661 scopus 로고
    • Alterations in expression and methylation of specific genes in livers of rats fed a cancer promoting methyl-deficient diet
    • Dizik M, Christman JK, Wainfan E (1991): Alterations in expression and methylation of specific genes in livers of rats fed a cancer promoting methyl-deficient diet. Carcinogenesis 12:1307-1312.
    • (1991) Carcinogenesis , vol.12 , pp. 1307-1312
    • Dizik, M.1    Christman, J.K.2    Wainfan, E.3
  • 22
    • 0027440979 scopus 로고
    • Cell death initiated by 3-deazaadenosine in HL-60 cells is apoptosis and is partially inhibited by homocysteine
    • Endresen PC, Eide TJ, Aarbakke J (1993): Cell death initiated by 3-deazaadenosine in HL-60 cells is apoptosis and is partially inhibited by homocysteine. Biochem Pharmacol 46:1893-1901.
    • (1993) Biochem Pharmacol , vol.46 , pp. 1893-1901
    • Endresen, P.C.1    Eide, T.J.2    Aarbakke, J.3
  • 23
    • 0028335913 scopus 로고
    • Homocysteine increases the relative number of apoptotic cells and reduces the relative number of apoptotic bodies in HL-60 cells treated with 3-deazaadenosine
    • Endresen PC, Prytz PS, Lysne S, Aarbakke J (1994): Homocysteine increases the relative number of apoptotic cells and reduces the relative number of apoptotic bodies in HL-60 cells treated with 3-deazaadenosine. J Pharmacol Exp Ther 269:1245-1253.
    • (1994) J Pharmacol Exp Ther , vol.269 , pp. 1245-1253
    • Endresen, P.C.1    Prytz, P.S.2    Lysne, S.3    Aarbakke, J.4
  • 24
    • 0021220516 scopus 로고
    • Methionine metabolism in mammals. Distribution of homocysteine between competing pathways
    • Finkelstein JD, Martin JJ (1984): Methionine metabolism in mammals. Distribution of homocysteine between competing pathways. J Biol Chem 259:9508-9513.
    • (1984) J Biol Chem , vol.259 , pp. 9508-9513
    • Finkelstein, J.D.1    Martin, J.J.2
  • 26
    • 0020615293 scopus 로고
    • Regulation of hepatic betaine-homocysteine methyltransferase by dietary betaine
    • Finkelstein JD, Martin JJ, Harris BJ, Kyle WE (1983): Regulation of hepatic betaine-homocysteine methyltransferase by dietary betaine. J Nutr 113:519-521.
    • (1983) J Nutr , vol.113 , pp. 519-521
    • Finkelstein, J.D.1    Martin, J.J.2    Harris, B.J.3    Kyle, W.E.4
  • 28
    • 0021157513 scopus 로고
    • The induction of liver cancer by dietary deficiency of choline and methionine without added carcinogens
    • Ghoshal AK, Farber E (1984): The induction of liver cancer by dietary deficiency of choline and methionine without added carcinogens. Carcinogenesis 5:1367-1370.
    • (1984) Carcinogenesis , vol.5 , pp. 1367-1370
    • Ghoshal, A.K.1    Farber, E.2
  • 30
    • 0028128625 scopus 로고
    • Directed cell killing (apoptosis) in human lymphoblastoid cells incubated in the presence of farnesol: Effect of phosphatidylcholine
    • Haug JS, Goldner CM, Yazlovitskaya EM, Voziyan PA, Melnykovych G (1994): Directed cell killing (apoptosis) in human lymphoblastoid cells incubated in the presence of farnesol: Effect of phosphatidylcholine. Biochim Biophys Acta 1223:133-140.
    • (1994) Biochim Biophys Acta , vol.1223 , pp. 133-140
    • Haug, J.S.1    Goldner, C.M.2    Yazlovitskaya, E.M.3    Voziyan, P.A.4    Melnykovych, G.5
  • 31
    • 0017650594 scopus 로고
    • Asymmetry of the phospholipid bilayer of rat liver endoplasmic reticulum
    • Higgins JA, Dawson RMC (1977): Asymmetry of the phospholipid bilayer of rat liver endoplasmic reticulum. Biochim Biophys Acta 470:342-356.
    • (1977) Biochim Biophys Acta , vol.470 , pp. 342-356
    • Higgins, J.A.1    Dawson, R.M.C.2
  • 32
    • 0029003018 scopus 로고
    • Expression of phosphatidylethanolamine N-methyltransferase-2 cannot compensate for an impaired CDP-choline pathway in mutant CHO cells
    • Houweling M, Z. C, Vance DE (1995): Expression of phosphatidylethanolamine N-methyltransferase-2 cannot compensate for an impaired CDP-choline pathway in mutant CHO cells. J Biol Chem 270:16277-16282.
    • (1995) J Biol Chem , vol.270 , pp. 16277-16282
    • Houweling, M.Z.C.1    Vance, D.E.2
  • 33
    • 0028146621 scopus 로고
    • Coordination of membrane phospholipid synthesis with the cell cycle
    • Jackowski S (1994): Coordination of membrane phospholipid synthesis with the cell cycle. J Biol Chem 269:3858-67.
    • (1994) J Biol Chem , vol.269 , pp. 3858-3867
    • Jackowski, S.1
  • 34
    • 0028072164 scopus 로고
    • In vitro folate deficiency induces deoxynucleotide pool imbalance, apoptosis, and mutagenesis in chinese hamster ovary cells
    • James SJ, Basnakian AG, Miller BJ (1994): In vitro folate deficiency induces deoxynucleotide pool imbalance, apoptosis, and mutagenesis in chinese hamster ovary cells. Cancer Res 54:5075-5080.
    • (1994) Cancer Res , vol.54 , pp. 5075-5080
    • James, S.J.1    Basnakian, A.G.2    Miller, B.J.3
  • 35
    • 0027912702 scopus 로고
    • Effects of the phospholipid environment in the plasma membrane on receptor interaction with the adenylyl cyclase complex of intact cells
    • Jansson C, Harmala A, Toivola DM, Slotte JP (1993): Effects of the phospholipid environment in the plasma membrane on receptor interaction with the adenylyl cyclase complex of intact cells. Biochim Biophys Acta 1145: 311-319.
    • (1993) Biochim Biophys Acta , vol.1145 , pp. 311-319
    • Jansson, C.1    Harmala, A.2    Toivola, D.M.3    Slotte, J.P.4
  • 36
    • 0028918256 scopus 로고
    • Generation of phosphatidylcholine as an essential event in the activation of Raf-1 and MAP-kinases in growth factors-induced mitogenic stimulation
    • Jimenez B, del Peso L, Montaner S, Esteve P, Lacal JC (1995): Generation of phosphatidylcholine as an essential event in the activation of Raf-1 and MAP-kinases in growth factors-induced mitogenic stimulation. J Cell Biochem 57:141-149.
    • (1995) J Cell Biochem , vol.57 , pp. 141-149
    • Jimenez, B.1    Del Peso, L.2    Montaner, S.3    Esteve, P.4    Lacal, J.C.5
  • 37
    • 0027631317 scopus 로고
    • Abnormal function of protein kinase C in cells having phosphatidylethanolamine-deficient and phosphatidylcholine-excess membranes
    • Kano-Sueoka T, Nicks ME (1993): Abnormal function of protein kinase C in cells having phosphatidylethanolamine-deficient and phosphatidylcholine-excess membranes. Cell Growth Differ 4:533-537.
    • (1993) Cell Growth Differ , vol.4 , pp. 533-537
    • Kano-Sueoka, T.1    Nicks, M.E.2
  • 38
    • 0015383455 scopus 로고
    • Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JFR, Wyllie AH, Currie AR (1972): Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.R.1    Wyllie, A.H.2    Currie, A.R.3
  • 40
    • 0028028307 scopus 로고
    • Multi-step chromatin degradation in apoptosis
    • Kokileva L (1994): Multi-step chromatin degradation in apoptosis. Int. Arch. Allergy Immunol 105:339-343.
    • (1994) Int. Arch. Allergy Immunol , vol.105 , pp. 339-343
    • Kokileva, L.1
  • 41
    • 0028221050 scopus 로고
    • Apoptosis mediates and thymidine prevents erythroblast destruction in folate deficiency anemia
    • Koury MJ, Horne DW (1994): Apoptosis mediates and thymidine prevents erythroblast destruction in folate deficiency anemia. Proc Natl Acad Sci USA 91:4067-71.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 4067-4071
    • Koury, M.J.1    Horne, D.W.2
  • 42
    • 0022758869 scopus 로고
    • DNA methylation and hepatocarcinogenesis in rats fed a choline devoid diet
    • Locker J, Reddy TV, Lombardi B (1986): DNA methylation and hepatocarcinogenesis in rats fed a choline devoid diet. Carcinogenesis 7:1309-1312.
    • (1986) Carcinogenesis , vol.7 , pp. 1309-1312
    • Locker, J.1    Reddy, T.V.2    Lombardi, B.3
  • 43
    • 0028297513 scopus 로고
    • Changes in phospholipids during the cell cycle of myxomycete Physarum polycephalum
    • Makarov PR, Rotaru VK, Polteva NA, Evtodienko YV (1994): Changes in phospholipids during the cell cycle of myxomycete Physarum polycephalum. FEBS Lett 344:47-49.
    • (1994) FEBS Lett , vol.344 , pp. 47-49
    • Makarov, P.R.1    Rotaru, V.K.2    Polteva, N.A.3    Evtodienko, Y.V.4
  • 44
    • 0000439435 scopus 로고
    • A method for the determination of betaine in tissues using high performance liquid chromatography
    • Mar MH, Ridky TW, Garner SC, Zeisel SH (1995): A method for the determination of betaine in tissues using high performance liquid chromatography. J Nutr Biochem 6:392-398.
    • (1995) J Nutr Biochem , vol.6 , pp. 392-398
    • Mar, M.H.1    Ridky, T.W.2    Garner, S.C.3    Zeisel, S.H.4
  • 46
    • 0021053494 scopus 로고
    • Hepatocarcinogenesis in rats fed methyl-deficient, amino acid-defined diets
    • Mikol YB, Hoover KL, Creasia D, Poirier LA (1983): Hepatocarcinogenesis in rats fed methyl-deficient, amino acid-defined diets. Carcinogenesis 4:1619-1629.
    • (1983) Carcinogenesis , vol.4 , pp. 1619-1629
    • Mikol, Y.B.1    Hoover, K.L.2    Creasia, D.3    Poirier, L.A.4
  • 47
    • 0025604366 scopus 로고
    • A new high performance liquid chromatographic method for the simultaneous measurement of S-adenosylmethionine and S-adenosylhomocysteine
    • Molloy AM, Weir DG, Kennedy G, Kennedy S, Scott JM (1990): A new high performance liquid chromatographic method for the simultaneous measurement of S-adenosylmethionine and S-adenosylhomocysteine. Biomed Chromatogr 4:257-260.
    • (1990) Biomed Chromatogr , vol.4 , pp. 257-260
    • Molloy, A.M.1    Weir, D.G.2    Kennedy, G.3    Kennedy, S.4    Scott, J.M.5
  • 48
    • 0022519625 scopus 로고
    • Labile methyl groups and the promotion of cancer
    • Newberne PM, Rogers AE (1986): Labile methyl groups and the promotion of cancer. Ann Rev Nutr 6:407-432.
    • (1986) Ann Rev Nutr , vol.6 , pp. 407-432
    • Newberne, P.M.1    Rogers, A.E.2
  • 49
    • 0018369993 scopus 로고
    • Lipid asymmetry in membranes
    • Op den Kamp JAF (1979): Lipid asymmetry in membranes. Ann Rev Biochem 48:47-71.
    • (1979) Ann Rev Biochem , vol.48 , pp. 47-71
    • Op Den Kamp, J.A.F.1
  • 51
    • 0024338009 scopus 로고
    • Measurement of choline and choline metabolite concentrations using high-pressure liquid chromatography and gas chromatography-mass spectrometry
    • Pomfret EA, daCosta K, Schurman LL, Zeisel SH (1989): Measurement of choline and choline metabolite concentrations using high-pressure liquid chromatography and gas chromatography-mass spectrometry. Anal Biochem 180:85-90.
    • (1989) Anal Biochem , vol.180 , pp. 85-90
    • Pomfret, E.A.1    DaCosta, K.2    Schurman, L.L.3    Zeisel, S.H.4
  • 52
    • 0025066220 scopus 로고
    • Effects of choline deficiency and methotrexate treatment upon rat liver
    • Pomfret EA, da Costa K, Zeisel SH (1990): Effects of choline deficiency and methotrexate treatment upon rat liver. J Nutr Biochem 1:533-541.
    • (1990) J Nutr Biochem , vol.1 , pp. 533-541
    • Pomfret, E.A.1    Da Costa, K.2    Zeisel, S.H.3
  • 53
    • 0023657097 scopus 로고
    • Purification of phosphatidylethanolamine N-methyltransferase from rat liver
    • Ridgway ND, Vance DE (1987): Purification of phosphatidylethanolamine N-methyltransferase from rat liver. J Biol Chem 262:17231-9.
    • (1987) J Biol Chem , vol.262 , pp. 17231-17239
    • Ridgway, N.D.1    Vance, D.E.2
  • 54
    • 0027358971 scopus 로고
    • Involvement of phospholipase D in caerulein-induced phosphatidylcholine hydrolysis in rat pancreatic acini
    • Rydzewska G, Rossignol B, Morisset J (1993): Involvement of phospholipase D in caerulein-induced phosphatidylcholine hydrolysis in rat pancreatic acini. Am J Physiol 265:G725-734.
    • (1993) Am J Physiol , vol.265
    • Rydzewska, G.1    Rossignol, B.2    Morisset, J.3
  • 55
    • 0022530610 scopus 로고
    • Lipid composition of subcellular particles from sheep platelets. Location of phosphatidylethanolamine and phosphatidylserine in plasma membranes and platelet liposomes
    • Sanchez-Yague J, Llanillo M (1986): Lipid composition of subcellular particles from sheep platelets. Location of phosphatidylethanolamine and phosphatidylserine in plasma membranes and platelet liposomes. Biochim Biophys Acta 856:193-201.
    • (1986) Biochim Biophys Acta , vol.856 , pp. 193-201
    • Sanchez-Yague, J.1    Llanillo, M.2
  • 56
    • 0027479977 scopus 로고
    • Apoptosis: The biochemistry and molecular biology of programmed cell death
    • Schwartzman RA, Cidlowski JA (1993): Apoptosis: The biochemistry and molecular biology of programmed cell death. Endocrinol Rev 14:133-151.
    • (1993) Endocrinol Rev , vol.14 , pp. 133-151
    • Schwartzman, R.A.1    Cidlowski, J.A.2
  • 58
    • 84982074785 scopus 로고
    • Plasma total lipids, cholesterol, triglycerides, phospholipids and free fatty acids in a healthy Scandanavian population
    • Svanborg A, Svennerholm L (1961): Plasma total lipids, cholesterol, triglycerides, phospholipids and free fatty acids in a healthy Scandanavian population. Acta Med Scand 169:43-49.
    • (1961) Acta Med Scand , vol.169 , pp. 43-49
    • Svanborg, A.1    Svennerholm, L.2
  • 59
    • 0022366262 scopus 로고
    • Rat brain phosphatidyl-N,N-dimethylethanolamine is rich in polyunsaturated fatty acids
    • Tacconi M, Wurtman RJ (1985): Rat brain phosphatidyl-N,N-dimethylethanolamine is rich in polyunsaturated fatty acids. J Neurochem 45:805-809.
    • (1985) J Neurochem , vol.45 , pp. 805-809
    • Tacconi, M.1    Wurtman, R.J.2
  • 60
    • 0018646528 scopus 로고
    • Induction of foci of altered hepatocytes by a single injection of azaserine to rats
    • Takahashi S, Katyal SL, Lombardi B, Shinozuka H (1979): Induction of foci of altered hepatocytes by a single injection of azaserine to rats. Cancer Lett 7:265-272.
    • (1979) Cancer Lett , vol.7 , pp. 265-272
    • Takahashi, S.1    Katyal, S.L.2    Lombardi, B.3    Shinozuka, H.4
  • 61
    • 0028584213 scopus 로고
    • Requirement of phosphatidylcholine for normal progression through the cell cycle in C3H/10T1/2 fibroblasts
    • Terce F, Brun H, Vance DE (1994): Requirement of phosphatidylcholine for normal progression through the cell cycle in C3H/10T1/2 fibroblasts. J Lipid Res 35:2130-2142.
    • (1994) J Lipid Res , vol.35 , pp. 2130-2142
    • Terce, F.1    Brun, H.2    Vance, D.E.3
  • 62
    • 0027152123 scopus 로고
    • Measurement of red blood cell-vitamin B12: A study of the correlation between intracellular B12 content and concentrations of plasma holotranscobalamin II
    • Tisman G, Vu T, Amin J, Luszko G, Brenner M, Ramos M, Flener V, Cordts V, Bateman R, Malkin S, Browder T (1993): Measurement of red blood cell-vitamin B12: A study of the correlation between intracellular B12 content and concentrations of plasma holotranscobalamin II. Am J Hematol 43:226-229.
    • (1993) Am J Hematol , vol.43 , pp. 226-229
    • Tisman, G.1    Vu, T.2    Amin, J.3    Luszko, G.4    Brenner, M.5    Ramos, M.6    Flener, V.7    Cordts, V.8    Bateman, R.9    Malkin, S.10    Browder, T.11
  • 63
    • 0027665370 scopus 로고
    • Endothelial cell phospholipid distribution and phospholipase activity during acute and chronic hypoxia
    • Tretyakov AV, Farber HW (1993): Endothelial cell phospholipid distribution and phospholipase activity during acute and chronic hypoxia. Am J Physiol 265:C770-C780.
    • (1993) Am J Physiol , vol.265
    • Tretyakov, A.V.1    Farber, H.W.2
  • 64
    • 0025134479 scopus 로고
    • Phosphatidylcholine metabolism: Masochistic enzymology, metabolic regulation, and lipoprotein assembly
    • Vance DE (1990): Phosphatidylcholine metabolism: Masochistic enzymology, metabolic regulation, and lipoprotein assembly. Biochem Cell Biol 68:1151-1165.
    • (1990) Biochem Cell Biol , vol.68 , pp. 1151-1165
    • Vance, D.E.1
  • 65
    • 0024257603 scopus 로고
    • The methylation of phosphatidylethanolamine
    • Vance DE, Ridgway ND (1988): The methylation of phosphatidylethanolamine. Prog Lipid Res 27:61-79.
    • (1988) Prog Lipid Res , vol.27 , pp. 61-79
    • Vance, D.E.1    Ridgway, N.D.2
  • 66
    • 0000244714 scopus 로고
    • Effect of chronic choline deficiency in rats on liver folate content and distribution
    • Varela-Moreiras G, Selhub J, da Costa K, Zeisel SH (1992): Effect of chronic choline deficiency in rats on liver folate content and distribution. J Nutr Biochem 3:519-522.
    • (1992) J Nutr Biochem , vol.3 , pp. 519-522
    • Varela-Moreiras, G.1    Selhub, J.2    Da Costa, K.3    Zeisel, S.H.4
  • 67
    • 0026579875 scopus 로고
    • Methyl groups in carcinogenesis: Effects on DNA methylation and gene expression
    • Wainfan E, Poirier LA (1992): Methyl groups in carcinogenesis: effects on DNA methylation and gene expression. Cancer Res 52:2071s-2077s.
    • (1992) Cancer Res , vol.52
    • Wainfan, E.1    Poirier, L.A.2
  • 68
    • 0023429407 scopus 로고
    • Regulation of albumin gene expression in a series of rat hepatocyte cell lines immortalized by simian virus 40 and maintained in chemically defined medium
    • Woodworth CD, Isom HC (1987): Regulation of albumin gene expression in a series of rat hepatocyte cell lines immortalized by simian virus 40 and maintained in chemically defined medium. Mol Cell Biol 7:3740-3748.
    • (1987) Mol Cell Biol , vol.7 , pp. 3740-3748
    • Woodworth, C.D.1    Isom, H.C.2
  • 69
    • 0022517789 scopus 로고
    • Transformation of rat hepatocytes by transfection with simian virus 40 DNA to yield proliferating differentiated cells
    • Woodworth CD, Secott T, Isom HC (1986): Transformation of rat hepatocytes by transfection with simian virus 40 DNA to yield proliferating differentiated cells. Cancer Res 46:4018-4026.
    • (1986) Cancer Res , vol.46 , pp. 4018-4026
    • Woodworth, C.D.1    Secott, T.2    Isom, H.C.3
  • 70
    • 0023715118 scopus 로고
    • Tumorigenicity of simian virus 40-hepatocyte cell lines: Effect of in vitro and in vivo passage on expression of liver-specific genes and oncogenes
    • Woodworth CD, Krieder JW, Mengel L, Miller T, Meng Y, Isom HC (1988): Tumorigenicity of simian virus 40-hepatocyte cell lines: Effect of in vitro and in vivo passage on expression of liver-specific genes and oncogenes. Mol Cell Biol 8:4492-4501.
    • (1988) Mol Cell Biol , vol.8 , pp. 4492-4501
    • Woodworth, C.D.1    Krieder, J.W.2    Mengel, L.3    Miller, T.4    Meng, Y.5    Isom, H.C.6
  • 71
    • 0001671420 scopus 로고
    • Cell death
    • Wyllie AH (1987): Cell death. Int. Rev. Cytol. 17(Suppl):755-785.
    • (1987) Int. Rev. Cytol. , vol.17 , Issue.SUPPL. , pp. 755-785
    • Wyllie, A.H.1
  • 73
    • 0024590370 scopus 로고
    • Effect of choline deficiency on S-adenosylmethionine and methionine concentrations in rat liver
    • Zeisel SH, Zola T, daCosta K, Pomfret EA (1989): Effect of choline deficiency on S-adenosylmethionine and methionine concentrations in rat liver. Biochem J 259:725-729.
    • (1989) Biochem J , vol.259 , pp. 725-729
    • Zeisel, S.H.1    Zola, T.2    Dacosta, K.3    Pomfret, E.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.