Evidence for a direct interaction between the Thr11 residue of vasoactive intestinal polypeptide and Tyr184 located in the first extracellular loop of the VPAC2 receptor

Biochemical Journal

Volumn 370, Issue 3, 2003, Pages 1003-1009

  Nachtergael, Ingrid ^a   Vertongen, Pascale ^a   Langer, Ingrid ^a   Perret, Jason ^a   Robberecht, Patrick ^a   Waelbroeck, Magali ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

VIP binding site; VPAC1 antagonist; VPAC1 selective agonist; VPAC2 receptor

Indexed keywords

CATALYST SELECTIVITY; ENZYMES; HYDROGEN BONDS; HYDROXYLATION;

LIGANDS;

POLYPEPTIDES;

ADENYLATE CYCLASE; ARGININE; HYDROXYL GROUP; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE RECEPTOR; LIGAND; RECEPTOR SUBTYPE; SECRETIN; THREONINE; TYROSINE; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE RECEPTOR;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CHIMERA; COMPARATIVE STUDY; ENZYME ACTIVATION; HYDROGEN BOND; MOLECULAR INTERACTION; MUTANT; PRIORITY JOURNAL;

ADENYLATE CYCLASE; CELL LINE; CELL MEMBRANE; GASTROINTESTINAL AGENTS; HYDROGEN BONDING; PEPTIDE FRAGMENTS; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE; RECEPTORS, VASOACTIVE INTESTINAL PEPTIDE, TYPE II; RECOMBINANT FUSION PROTEINS; THREONINE; TYROSINE; VASOACTIVE INTESTINAL PEPTIDE;

EID: 0037444808     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20020811     Document Type: Article

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