Pharmacokinetics of metronidazole in rat blood, brain and bile studied by microdialysis coupled to microbore liquid chromatography

Journal of Chromatography A

Volumn 987, Issue 1-2, 2003, Pages 277-282

  Tsai, Tung Hu ^a,b   Chen, Yen Fei ^a  

^a NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Metronidazole; Microdialysis

Indexed keywords

BLOOD; BRAIN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PROTEINS; SODIUM COMPOUNDS;

ANTIBACTERIAL AGENTS;

PHARMACOKINETICS;

ACETONITRILE; BUFFER; CYTOCHROME P450; GLYCOPROTEIN P; METRONIDAZOLE; SODIUM DIHYDROGEN PHOSPHATE; TRIETHYLAMINE;

AREA UNDER THE CURVE; BLOOD BRAIN BARRIER; CONFERENCE PAPER; DRUG BILE LEVEL; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DETERMINATION; DRUG EXCRETION; DRUG PENETRATION; LIQUID CHROMATOGRAPHY; MALE; MICRODIALYSIS; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-INFECTIVE AGENTS; BILE; BLOOD-BRAIN BARRIER; BRAIN; MALE; METRONIDAZOLE; MICRODIALYSIS; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY;

NEGIBACTERIA;

EID: 0037435896     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9673(02)01454-1     Document Type: Conference Paper

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