New semisynthetic quassinoids with in vivo antimalarial activity

Journal of Medicinal Chemistry

Volumn 46, Issue 4, 2003, Pages 638-641

  Murakami, Nobutoshi ^a   Sugimoto, Masanori ^a   Kawanishi, Motoyuki ^a   Tamura, Satoru ^a   Kim, Hye Sook ^b   Begum, Khurshida ^b   Wataya, Yusuke ^b   Kobayashi, Motomasa ^a  

^a OSAKA UNIVERSITY   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

15 O ACETYLBRUCEOLIDE; 3,15 DI O ACETYLBRUCEOLIDE; BRUCEOLIDE 15 METHYL CARBONATE; BRUCEOLIDE DERIVATIVE; CARBONIC ACID DERIVATIVE; CHLOROQUINE; QUASSINOID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DIARRHEA; DRUG CYTOTOXICITY; DRUG FATALITY; DRUG MECHANISM; DRUG POTENCY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; LIFESPAN; MOUSE; NONHUMAN; PLASMODIUM FALCIPARUM; SURVIVAL RATE; WEIGHT REDUCTION;

ANIMALS; ANTIMALARIALS; DRUG STABILITY; MALARIA; MICE; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; QUASSINS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0037434546     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0201971     Document Type: Article

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