Antimalarial and cytotoxic potential of four quassinoids from Hannoa chlorantha and Hannoa klaineana, and their structure-activity relationships

International Journal for Parasitology

Volumn 28, Issue 4, 1998, Pages 635-640

  François, Guido ^a   Diakanamwa, Carlos ^b   Timperman, Georges ^a   Bringmann, Gerhard ^c   Steenackers, Tania ^a   Atassi, Ghanem ^b   Van Looveren, Marleen ^a   Holenz, Jörg ^c   Tassin, Jean Pierre ^b   Assi, Laurent Aké ^d   Vanhaelen Fastré, Renée ^b   Vanhaelen, Maurice ^b  

^a INSTITUTE OF TROPICAL MEDICINE   (Belgium)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITÉ NANGUI ABROGOUA   (Côte d’Ivoire)

Author keywords

Cytotoxicity; Hannoa chlorantha; Hannoa klaineana; Malaria; P 388 cells; Plasmodium berghei in vivo; Plasmodium falciparum in vitro; Quassinoids; Simaroubaceae

Indexed keywords

QUASSINOID;

MALARIA; PLANT EXTRACT; QUASSINOID;

ANTIMALARIAL ACTIVITY; ARTICLE; CYTOTOXICITY; DRUG EFFECT; HUMAN; LEUKEMIA P 388; MALARIA; PARASITEMIA; PHYTOCHEMISTRY; STRUCTURE ACTIVITY RELATION; TRADITIONAL MEDICINE;

ANIMALS; ANTIMALARIALS; CELL SURVIVAL; FEMALE; GLAUCARUBIN; LEUKEMIA P388; MALARIA; MICE; PLANT EXTRACTS; PLANT ROOTS; PLANTS, MEDICINAL; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; QUASSINS; SEEDS; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

HANNOA; HANNOA CHLORANTHA; HANNOA KLAINEANA; NEMATODA; PLASMODIUM BERGHEI; PLASMODIUM FALCIPARUM; SIMAROUBACEAE;

EID: 0032055868     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(98)00008-3     Document Type: Article

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