Effect of synthesized cyclohexanol derivatives using L-menthol as a lead compound on the percutaneous absorption of ketoprofen

International Journal of Pharmaceutics

Volumn 198, Issue 2, 2000, Pages 191-200

  Obata, Yasuko ^a   Sato, Haruka ^a   Li, Chao Jie ^a   Takayama, Kozo ^a   Higashiyama, Kimio ^a   Nagai, Tsuneji ^a   Isowa, Koichi ^b  

^a HOSHI UNIVERSITY   (Japan)

^b Ctr of Japan Biol Chem Co Ltd   (Japan)

Author keywords

Cyclohexanol derivatives; Ketoprofen; L Menthol; Lead compound; Percutaneous absorption enhancer

Indexed keywords

ALCOHOL; CARBOMER; CYCLOHEXANE; CYCLOHEXANOL DERIVATIVE; HIVISWAKO 105; KETOPROFEN; MENTHOL; O ETHYLMENTHOL; PENETRATION ENHANCING AGENT; POLYACRYLIC ACID; TRIETHANOLAMINE; UNCLASSIFIED DRUG; WATER;

ABDOMEN; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG SYNTHESIS; HISTOPATHOLOGY; HYDROGEL; LIPOPHILICITY; MALE; MICROSCOPY; MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHARMACOPHORE; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; RAT; REGRESSION ANALYSIS; SKIN ABSORPTION; SKIN IRRITATION; STRUCTURE ACTIVITY RELATION; TECHNIQUE;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYCLOHEXANOLS; IRRITANTS; KETOPROFEN; MALE; MENTHOL; RATS; RATS, WISTAR; SKIN ABSORPTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0034607282     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(00)00328-8     Document Type: Article

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