The hypolipidemic drug metabolites nafenopin-CoA and ciprofibroyl-CoA are competitive P2Y1 receptor antagonists

FEBS Letters

Volumn 536, Issue 1-3, 2003, Pages 145-150

  Coddou, Claudio ^a   Loyola, Gloria ^a   Boyer, José Luis ^b   Bronfman, Miguel ^a   Huidobro Toro, J Pablo ^a  

^a PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Acyl CoA derivatives; Ciprofibroyl CoA; Competitive antagonism; Fibrates; Hypolipidemic drugs; Nafenopin CoA; P2Y1 receptor antagonists; Palmitoyl CoA

Indexed keywords

ADENOSINE TRIPHOSPHATE; ANTILIPEMIC AGENT; CIPROFIBROYL; COENZYME A; DRUG DERIVATIVE; DRUG METABOLITE; NAFENOPIN; PALMITOYLCARNITINE; PURINE P2Y RECEPTOR; RECEPTOR; RECEPTOR BLOCKING AGENT; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHLORIDE CURRENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; HYDROPHOBICITY; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; XENOPUS LAEVIS;

XENOPUS LAEVIS;

EID: 0037432178     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(03)00044-9     Document Type: Article

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