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Volumn 117, Issue 4, 2003, Pages 949-955

Attenuation of N-methyl-D-aspartate-mediated cytoplasmic vacuolization in primary rat hippocampal neurons by mood stabilizers

Author keywords

Carbamazepine; Lithium; Neuroprotection; Transmission electron microscopy; Vacuolization; Valproate

Indexed keywords

CARBAMAZEPINE; LITHIUM; N METHYL DEXTRO ASPARTIC ACID; VALPROIC ACID;

EID: 0037430761     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(02)00743-1     Document Type: Article
Times cited : (36)

References (59)
  • 1
    • 0032575688 scopus 로고    scopus 로고
    • The Bcl-2 protein family: Arbiters of cell survival
    • Adams J.M., Cory S. The Bcl-2 protein family arbiters of cell survival . Science. 281:1998;1322-1326.
    • (1998) Science , vol.281 , pp. 1322-1326
    • Adams, J.M.1    Cory, S.2
  • 2
    • 18244425608 scopus 로고    scopus 로고
    • Carbamazepine inhibits L-type Ca2+ channels in cultured rat hippocampal neurons stimulated with glutamate receptor agonists
    • Ambrosio A.F., Silva A.P., Malva J.O., Soares-da-Silva P., Carvalho A.P., Carvalho C.M. Carbamazepine inhibits L-type Ca2+ channels in cultured rat hippocampal neurons stimulated with glutamate receptor agonists. Neuropharmacology. 38:1999;1349-1359.
    • (1999) Neuropharmacology , vol.38 , pp. 1349-1359
    • Ambrosio, A.F.1    Silva, A.P.2    Malva, J.O.3    Soares-da-Silva, P.4    Carvalho, A.P.5    Carvalho, C.M.6
  • 3
    • 0017350927 scopus 로고
    • Rat hippocampal neurons in dispersed cell culture
    • Banker G.A., Cowan W.M. Rat hippocampal neurons in dispersed cell culture. Brain Res. 126:1977;1349-1359.
    • (1977) Brain Res , vol.126 , pp. 1349-1359
    • Banker, G.A.1    Cowan, W.M.2
  • 4
    • 0021629684 scopus 로고
    • An electron microscopic study of the development of axons and dendrites by hippocampal neurons in culture. I. Cells which develop without intercellular contacts
    • Bartlett W.P., Banker G.A. An electron microscopic study of the development of axons and dendrites by hippocampal neurons in culture. I. Cells which develop without intercellular contacts. J Neurosci. 4:1984;1944-1953.
    • (1984) J Neurosci , vol.4 , pp. 1944-1953
    • Bartlett, W.P.1    Banker, G.A.2
  • 5
    • 0035884325 scopus 로고    scopus 로고
    • The density of pyramidal and nonpyramidal neurons in anterior cingulate cortex of schizophrenic and bipolar subjects
    • Benes F.M., Vincent S.L., Todtenkopf M. The density of pyramidal and nonpyramidal neurons in anterior cingulate cortex of schizophrenic and bipolar subjects. Biol Psychiatry. 50:2001;395-406.
    • (2001) Biol Psychiatry , vol.50 , pp. 395-406
    • Benes, F.M.1    Vincent, S.L.2    Todtenkopf, M.3
  • 6
    • 0033845743 scopus 로고    scopus 로고
    • Increased expression of endoplasmic reticulum stress proteins following chronic valproate treatment of rat C6 glioma cells
    • Bown C.D., Wang J., Young L.T. Increased expression of endoplasmic reticulum stress proteins following chronic valproate treatment of rat C6 glioma cells. Neuropharmacology. 39:2000;2162-2169.
    • (2000) Neuropharmacology , vol.39 , pp. 2162-2169
    • Bown, C.D.1    Wang, J.2    Young, L.T.3
  • 8
    • 0032864797 scopus 로고    scopus 로고
    • Regeneration and proliferation of embryonic and adult rat hippocampal neurons in culture
    • Brewer G.J. Regeneration and proliferation of embryonic and adult rat hippocampal neurons in culture. Exp Neurol. 159:1999;237-247.
    • (1999) Exp Neurol , vol.159 , pp. 237-247
    • Brewer, G.J.1
  • 9
    • 0027226219 scopus 로고
    • Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination
    • Brewer G.J., Torricelli J.R., Evege E.K., Price P.J. Optimized survival of hippocampal neurons in B27-supplemented Neurobasal, a new serum-free medium combination. J Neurosci Res. 35:1993;567-576.
    • (1993) J Neurosci Res , vol.35 , pp. 567-576
    • Brewer, G.J.1    Torricelli, J.R.2    Evege, E.K.3    Price, P.J.4
  • 11
    • 0033995265 scopus 로고    scopus 로고
    • Dual responses of CNS mitochondria to elevated calcium
    • Brustovetsky N., Dubinsky J.M. Dual responses of CNS mitochondria to elevated calcium. J Neurosci. 20:2000;103-113.
    • (2000) J Neurosci , vol.20 , pp. 103-113
    • Brustovetsky, N.1    Dubinsky, J.M.2
  • 13
    • 0033064346 scopus 로고    scopus 로고
    • Lithium and valproate differentially regulate brain regional expression of phosphorylated CREB and c-Fos
    • Chen B., Wang J.F., Hill B.C., Young L.T. Lithium and valproate differentially regulate brain regional expression of phosphorylated CREB and c-Fos. Brain Res Mol Brain Res. 70:1999;45-53.
    • (1999) Brain Res Mol Brain Res , vol.70 , pp. 45-53
    • Chen, B.1    Wang, J.F.2    Hill, B.C.3    Young, L.T.4
  • 14
    • 0034307061 scopus 로고    scopus 로고
    • Chronic valproate treatment increases expression of endoplasmic reticulum stress proteins in the rat cerebral cortex and hippocampus
    • Chen B., Wang J.F., Young L.T. Chronic valproate treatment increases expression of endoplasmic reticulum stress proteins in the rat cerebral cortex and hippocampus. Biol Psychiatry. 48:2000;658-664.
    • (2000) Biol Psychiatry , vol.48 , pp. 658-664
    • Chen, B.1    Wang, J.F.2    Young, L.T.3
  • 15
    • 0034307061 scopus 로고    scopus 로고
    • Chronic valproate treatment increases expression of endoplasmic reticulum stress proteins in the rat cerebral cortex and hippocampus
    • Chen B., Wang J.F., Young L.T. Chronic valproate treatment increases expression of endoplasmic reticulum stress proteins in the rat cerebral cortex and hippocampus. Biol Psychiatry. 48:2000;658-664.
    • (2000) Biol Psychiatry , vol.48 , pp. 658-664
    • Chen, B.1    Wang, J.F.2    Young, L.T.3
  • 16
    • 0033014180 scopus 로고    scopus 로고
    • The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3
    • Chen G., Huang L.D., Jiang Y.M., Manji H.K. The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3. J Neurochem. 72:1999;1327-1330.
    • (1999) J Neurochem , vol.72 , pp. 1327-1330
    • Chen, G.1    Huang, L.D.2    Jiang, Y.M.3    Manji, H.K.4
  • 17
    • 0032956630 scopus 로고    scopus 로고
    • The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS
    • Chen G., Zeng W.Z., Yuan P.X., et al. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. J Neurochem. 72:1999;879-882.
    • (1999) J Neurochem , vol.72 , pp. 879-882
    • Chen, G.1    Zeng, W.Z.2    Yuan, P.X.3
  • 18
    • 0033525538 scopus 로고    scopus 로고
    • Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity
    • Chen R.W., Chuang D.M. Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity. J Biol Chem. 274:1999;6039-6042.
    • (1999) J Biol Chem , vol.274 , pp. 6039-6042
    • Chen, R.W.1    Chuang, D.M.2
  • 19
    • 0032493304 scopus 로고    scopus 로고
    • Lithium acutely inhibits and chronically up-regulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex
    • Dixon J.F., Hokin L.E. Lithium acutely inhibits and chronically up-regulates and stabilizes glutamate uptake by presynaptic nerve endings in mouse cerebral cortex. Proc Natl Acad Sci USA. 95:1998;8363-8368.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 8363-8368
    • Dixon, J.F.1    Hokin, L.E.2
  • 20
    • 0034722688 scopus 로고    scopus 로고
    • Increased hippocampal supragranular Timm staining in subjects with bipolar disorder
    • Dowlatshahi D., MacQueen G., Wang J.F., Chen B., Young L.T. Increased hippocampal supragranular Timm staining in subjects with bipolar disorder. Neuroreport. 11:2000;3775-3778.
    • (2000) Neuroreport , vol.11 , pp. 3775-3778
    • Dowlatshahi, D.1    MacQueen, G.2    Wang, J.F.3    Chen, B.4    Young, L.T.5
  • 21
    • 0008024807 scopus 로고    scopus 로고
    • Hippocampal synaptic pathology in schizophrenia, bipolar disorder and major depression: A study of complexin mRNAs
    • Eastwood S.L., Harrison P.J. Hippocampal synaptic pathology in schizophrenia, bipolar disorder and major depression a study of complexin mRNAs . Mol Psychiatry. 5:2000;425-432.
    • (2000) Mol Psychiatry , vol.5 , pp. 425-432
    • Eastwood, S.L.1    Harrison, P.J.2
  • 22
    • 0033646608 scopus 로고    scopus 로고
    • Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression
    • 571
    • Fatemi S.H., Earle J.A., McMenomy T. Reduction in Reelin immunoreactivity in hippocampus of subjects with schizophrenia, bipolar disorder and major depression. Mol Psychiatry. 5:2000;654-663. 571.
    • (2000) Mol Psychiatry , vol.5 , pp. 654-663
    • Fatemi, S.H.1    Earle, J.A.2    McMenomy, T.3
  • 23
    • 0035968891 scopus 로고    scopus 로고
    • Altered levels of the synaptosomal associated protein SNAP-25 in hippocampus of subjects with mood disorders and schizophrenia
    • Fatemi S.H., Earle J.A., Stary J.M., Lee S., Sedgewick J. Altered levels of the synaptosomal associated protein SNAP-25 in hippocampus of subjects with mood disorders and schizophrenia. Neuroreport. 12:2001;3257-3262.
    • (2001) Neuroreport , vol.12 , pp. 3257-3262
    • Fatemi, S.H.1    Earle, J.A.2    Stary, J.M.3    Lee, S.4    Sedgewick, J.5
  • 25
    • 0028632818 scopus 로고
    • Confocal microscopic visualization of MK-801-induced cytoplasmic vacuoles in vitro
    • Freeman J.K., Goldberg M.P. Confocal microscopic visualization of MK-801-induced cytoplasmic vacuoles in vitro. Psychopharmacol Bull. 30:1994;541-547.
    • (1994) Psychopharmacol Bull , vol.30 , pp. 541-547
    • Freeman, J.K.1    Goldberg, M.P.2
  • 26
    • 0002545795 scopus 로고
    • Taxol attenuates glutamate receptor-mediated neurite swelling in vitro
    • Goldberg M.P., Bateman M.C. Taxol attenuates glutamate receptor-mediated neurite swelling in vitro. Soc Neurosci Abstr. 19:1993;26.
    • (1993) Soc Neurosci Abstr , vol.19 , pp. 26
    • Goldberg, M.P.1    Bateman, M.C.2
  • 27
    • 0036328597 scopus 로고    scopus 로고
    • Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons: Involvement of NMDA receptor inhibition possibly by decreasing N2RB tyrosine phosphorylation
    • Hashimoto R., Hough C., Nakazawa T., Yamamoto T., Chuang D.M. Lithium protection against glutamate excitotoxicity in rat cerebral cortical neurons involvement of NMDA receptor inhibition possibly by decreasing N2RB tyrosine phosphorylation . J Neurochem. 80:2002;589-597.
    • (2002) J Neurochem , vol.80 , pp. 589-597
    • Hashimoto, R.1    Hough, C.2    Nakazawa, T.3    Yamamoto, T.4    Chuang, D.M.5
  • 28
    • 0035006403 scopus 로고    scopus 로고
    • Up-regulation of hippocampal glutamate transport during chronic treatment with sodium valproate
    • Hassel B., Iversen E.G., Gjerstad L., Tauboll E. Up-regulation of hippocampal glutamate transport during chronic treatment with sodium valproate. J Neurochem. 77:2001;1285-1292.
    • (2001) J Neurochem , vol.77 , pp. 1285-1292
    • Hassel, B.1    Iversen, E.G.2    Gjerstad, L.3    Tauboll, E.4
  • 29
    • 0027793209 scopus 로고
    • Transient cytoplasmic vacuolization in cultured normal and neoplastic cells treated with low molecular weight human serum ultrafiltrate: Is out inside?
    • Henics T., Koszegi T., Szucs G., Kellermayer M.S. Jr., Kellermayer M. Transient cytoplasmic vacuolization in cultured normal and neoplastic cells treated with low molecular weight human serum ultrafiltrate is out inside? Physiol Chem Phys Med NMR. 25:1993;227-236.
    • (1993) Physiol Chem Phys Med NMR , vol.25 , pp. 227-236
    • Henics, T.1    Koszegi, T.2    Szucs, G.3    Kellermayer M.S., Jr.4    Kellermayer, M.5
  • 30
    • 0030665806 scopus 로고    scopus 로고
    • Vacuolar cytoplasmic phase separation in cultured mammalian cells involves the microfilament network and reduces motional properties of intracellular water
    • Henics T., Wheatley D.N. Vacuolar cytoplasmic phase separation in cultured mammalian cells involves the microfilament network and reduces motional properties of intracellular water. Int J Exp Pathol. 78:1997;343-354.
    • (1997) Int J Exp Pathol , vol.78 , pp. 343-354
    • Henics, T.1    Wheatley, D.N.2
  • 31
    • 0033177892 scopus 로고    scopus 로고
    • Cytoplasmic vacuolation, adaptation and cell death: A view on new perspectives and features
    • Henics T., Wheatley D.N. Cytoplasmic vacuolation, adaptation and cell death a view on new perspectives and features . Biol Cell. 91:1999;485-498.
    • (1999) Biol Cell , vol.91 , pp. 485-498
    • Henics, T.1    Wheatley, D.N.2
  • 32
    • 0029670389 scopus 로고    scopus 로고
    • Carbamazepine inhibition of N-methyl-D-aspartate-evoked calcium influx in rat cerebellar granule cells
    • Hough C.J., Irwin R.P., Gao X.M., Rogawski M.A., Chuang D.M. Carbamazepine inhibition of N-methyl-D-aspartate-evoked calcium influx in rat cerebellar granule cells. J Pharmacol Exp Ther. 276:1996;143-149.
    • (1996) J Pharmacol Exp Ther , vol.276 , pp. 143-149
    • Hough, C.J.1    Irwin, R.P.2    Gao, X.M.3    Rogawski, M.A.4    Chuang, D.M.5
  • 34
    • 0035903772 scopus 로고    scopus 로고
    • Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses
    • Law A.J., Deakin J.F. Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses. Neuroreport. 12:2001;2971-2974.
    • (2001) Neuroreport , vol.12 , pp. 2971-2974
    • Law, A.J.1    Deakin, J.F.2
  • 35
    • 0026567408 scopus 로고
    • Chronic lithium administration alters a prominent PKC substrate in rat hippocampus
    • Lenox R.H., Watson D.G., Patel J., Ellis J. Chronic lithium administration alters a prominent PKC substrate in rat hippocampus. Brain Res. 570:1992;333-340.
    • (1992) Brain Res , vol.570 , pp. 333-340
    • Lenox, R.H.1    Watson, D.G.2    Patel, J.3    Ellis, J.4
  • 36
    • 0030765016 scopus 로고    scopus 로고
    • Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells
    • Liu H., Bowes R.C. III, van de Water B., Sillence C., Nagelkerke J.F., Stevens J.L. Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells. J Biol Chem. 272:1997;21751-21759.
    • (1997) J Biol Chem , vol.272 , pp. 21751-21759
    • Liu, H.1    Bowes R.C. III2    Van de Water, B.3    Sillence, C.4    Nagelkerke, J.F.5    Stevens, J.L.6
  • 38
    • 0034667299 scopus 로고    scopus 로고
    • Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: Implications for the pathophysiology and treatment of manic-depressive illness
    • Manji H.K., Moore G.J., Chen G. Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers implications for the pathophysiology and treatment of manic-depressive illness . Biol Psychiatry. 48:2000;740-754.
    • (2000) Biol Psychiatry , vol.48 , pp. 740-754
    • Manji, H.K.1    Moore, G.J.2    Chen, G.3
  • 39
    • 0009789399 scopus 로고    scopus 로고
    • Lithium up-regulates the cytoprotective protein Bcl-2 in the CNS in vivo: A role for neurotrophic and neuroprotective effects in manic depressive illness
    • Manji H.K., Moore G.J., Chen G. Lithium up-regulates the cytoprotective protein Bcl-2 in the CNS in vivo a role for neurotrophic and neuroprotective effects in manic depressive illness . J Clin Psychiatry. 61:(Suppl 9):2000;82-96.
    • (2000) J Clin Psychiatry , vol.61 , Issue.SUPPL. 9 , pp. 82-96
    • Manji, H.K.1    Moore, G.J.2    Chen, G.3
  • 40
    • 0034981862 scopus 로고    scopus 로고
    • Bipolar disorder: Leads from the molecular and cellular mechanisms of action of mood stabilizers
    • Manji H.K., Moore G.J., Chen G. Bipolar disorder leads from the molecular and cellular mechanisms of action of mood stabilizers . Br J Psychiatry Suppl. 41:2001;s107-s119.
    • (2001) Br J Psychiatry Suppl , vol.41
    • Manji, H.K.1    Moore, G.J.2    Chen, G.3
  • 41
    • 0022616299 scopus 로고
    • Cell damage in epilepsy and the role of calcium in cytotoxicity
    • Meldrum B.S. Cell damage in epilepsy and the role of calcium in cytotoxicity. Adv Neurol. 44:1986;849-855.
    • (1986) Adv Neurol , vol.44 , pp. 849-855
    • Meldrum, B.S.1
  • 43
    • 0033572981 scopus 로고    scopus 로고
    • Different mechanisms of protection against apoptosis by valproate and Li+ Dentate granule neuron apoptosis and glia activation in murine hippocampus induced by trimethyltin exposure
    • Mora A., Gonzalez-Polo R.A., Fuentes J.M., et al. Different mechanisms of protection against apoptosis by valproate and Li+ Dentate granule neuron apoptosis and glia activation in murine hippocampus induced by trimethyltin exposure. Brain Res. 266:1999;886-891.
    • (1999) Brain Res , vol.266 , pp. 886-891
    • Mora, A.1    Gonzalez-Polo, R.A.2    Fuentes, J.M.3
  • 44
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival application to proliferation and cytotoxicity assays . J Immunol Methods. 65:1983;55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 45
    • 0027957793 scopus 로고
    • A set of endoplasmic reticulum proteins possessing properties of molecular chaperones includes Ca(2+)-binding proteins and members of the thioredoxin superfamily
    • Nigam S.K., Goldberg A.L., Ho S., Rohde M.F., Bush K.T., Sherman M.Y. A set of endoplasmic reticulum proteins possessing properties of molecular chaperones includes Ca(2+)-binding proteins and members of the thioredoxin superfamily. J Biol Chem. 269:1994;1744-1749.
    • (1994) J Biol Chem , vol.269 , pp. 1744-1749
    • Nigam, S.K.1    Goldberg, A.L.2    Ho, S.3    Rohde, M.F.4    Bush, K.T.5    Sherman, M.Y.6
  • 46
    • 0035961583 scopus 로고    scopus 로고
    • A volumetric magnetic resonance imaging study of monozygotic twins discordant for bipolar disorder
    • Noga J.T., Vladar K., Torrey E.F. A volumetric magnetic resonance imaging study of monozygotic twins discordant for bipolar disorder. Psychiatry Res. 106:2001;25-34.
    • (2001) Psychiatry Res , vol.106 , pp. 25-34
    • Noga, J.T.1    Vladar, K.2    Torrey, E.F.3
  • 47
    • 0032478088 scopus 로고    scopus 로고
    • Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx
    • Nonaka S., Hough C.J., Chuang D.M. Chronic lithium treatment robustly protects neurons in the central nervous system against excitotoxicity by inhibiting N-methyl-D-aspartate receptor-mediated calcium influx. Proc Natl Acad Sci USA. 95:1998;2642-2647.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2642-2647
    • Nonaka, S.1    Hough, C.J.2    Chuang, D.M.3
  • 48
    • 0024338054 scopus 로고
    • Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs
    • Olney J.W., Labruyere J., Price M.T. Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science. 244:1989;1360-1362.
    • (1989) Science , vol.244 , pp. 1360-1362
    • Olney, J.W.1    Labruyere, J.2    Price, M.T.3
  • 50
    • 0035119996 scopus 로고    scopus 로고
    • Pharmacological characterization of locomotor sensitization induced by chronic phencyclidine administration
    • Phillips M., Wang C., Johnson K.M. Pharmacological characterization of locomotor sensitization induced by chronic phencyclidine administration. J Pharmacol Exp Ther. 296:2001;905-913.
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 905-913
    • Phillips, M.1    Wang, C.2    Johnson, K.M.3
  • 51
    • 0025374197 scopus 로고
    • Reversible mitochondrial swelling in cultured rat hepatocytes exposed to 1,2-dimethylhydrazine
    • Pollanen M.S., Quinn B.A., Wollenberg G.K., Hayes M.A. Reversible mitochondrial swelling in cultured rat hepatocytes exposed to 1,2-dimethylhydrazine. Exp Mol Pathol. 52:1990;170-178.
    • (1990) Exp Mol Pathol , vol.52 , pp. 170-178
    • Pollanen, M.S.1    Quinn, B.A.2    Wollenberg, G.K.3    Hayes, M.A.4
  • 52
    • 0034637845 scopus 로고    scopus 로고
    • NMDA blockade attenuates caspase-3 activation and DNA fragmentation after neonatal hypoxia-ischemia
    • Puka-Sundvall M., Hallin U., Zhu C., et al. NMDA blockade attenuates caspase-3 activation and DNA fragmentation after neonatal hypoxia-ischemia. Neuroreport. 11:2000;2833-2836.
    • (2000) Neuroreport , vol.11 , pp. 2833-2836
    • Puka-Sundvall, M.1    Hallin, U.2    Zhu, C.3
  • 53
    • 0033048832 scopus 로고    scopus 로고
    • Brain magnetic resonance imaging of structural abnormalities in bipolar disorder
    • Strakowski S.M., DelBello M.P., Sax K.W., et al. Brain magnetic resonance imaging of structural abnormalities in bipolar disorder. Arch Gen Psychiatry. 56:1999;254-260.
    • (1999) Arch Gen Psychiatry , vol.56 , pp. 254-260
    • Strakowski, S.M.1    DelBello, M.P.2    Sax, K.W.3
  • 54
    • 0032704403 scopus 로고    scopus 로고
    • Distinct endoplasmic reticulum signaling pathways regulate apoptotic and necrotic cell death following iodoacetamide treatment
    • van deWater B., Wang Y., Asmellash S., et al. Distinct endoplasmic reticulum signaling pathways regulate apoptotic and necrotic cell death following iodoacetamide treatment. Chem Res Toxicol. 12:1999;943-951.
    • (1999) Chem Res Toxicol , vol.12 , pp. 943-951
    • Van deWater, B.1    Wang, Y.2    Asmellash, S.3
  • 55
    • 0032705455 scopus 로고    scopus 로고
    • Alterations of hippocampal secreted N-CAM in bipolar disorder and synaptophysin in schizophrenia
    • Vawter M.P., Howard A.L., Hyde T.M., Kleinman J.E., Freed W.J. Alterations of hippocampal secreted N-CAM in bipolar disorder and synaptophysin in schizophrenia. Mol Psychiatry. 4:1999;467-475.
    • (1999) Mol Psychiatry , vol.4 , pp. 467-475
    • Vawter, M.P.1    Howard, A.L.2    Hyde, T.M.3    Kleinman, J.E.4    Freed, W.J.5
  • 56
    • 0000434165 scopus 로고    scopus 로고
    • Sequestration of glutamate-induced Ca2+ loads by mitochondria in cultured rat hippocampal neurons
    • Wang G.J., Thayer S.A. Sequestration of glutamate-induced Ca2+ loads by mitochondria in cultured rat hippocampal neurons. J Neurophysiol. 7:1996;1611-1621.
    • (1996) J Neurophysiol , vol.7 , pp. 1611-1621
    • Wang, G.J.1    Thayer, S.A.2
  • 57
    • 0033050865 scopus 로고    scopus 로고
    • Differential display PCR reveals novel targets for the mood-stabilizing drug valproate including the molecular chaperone GRP78
    • Wang J.F., Bown C., Young L.T. Differential display PCR reveals novel targets for the mood-stabilizing drug valproate including the molecular chaperone GRP78. Mol Pharmacol. 55:1999;521-527.
    • (1999) Mol Pharmacol , vol.55 , pp. 521-527
    • Wang, J.F.1    Bown, C.2    Young, L.T.3
  • 58
    • 0031981038 scopus 로고    scopus 로고
    • Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells: A property of protein kinase C-mediated mood stabilizers
    • Watson D.G., Watterson J.M., Lenox R.H. Sodium valproate down-regulates the myristoylated alanine-rich C kinase substrate (MARCKS) in immortalized hippocampal cells a property of protein kinase C-mediated mood stabilizers . J Pharmacol Exp Ther. 285:1998;307-316.
    • (1998) J Pharmacol Exp Ther , vol.285 , pp. 307-316
    • Watson, D.G.1    Watterson, J.M.2    Lenox, R.H.3
  • 59
    • 0033015485 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: Suppression of oxidative stress and stabilization of calcium homeostasis
    • Yu Z., Luo H., Fu W., Mattson M.P. The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis suppression of oxidative stress and stabilization of calcium homeostasis . Exp Neurol. 155:1999;302-314.
    • (1999) Exp Neurol , vol.155 , pp. 302-314
    • Yu, Z.1    Luo, H.2    Fu, W.3    Mattson, M.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.