Effects of E-cadherin transfection on gene expression of a gallbladder carcinoma cell line: Repression of MTS1/S100A4 gene expression

International Journal of Cancer

Volumn 104, Issue 1, 2003, Pages 44-53

  Kohya, Naohiko ^a   Kitajima, Yoshihiko ^a   Jiao, Wan ^a   Miyazaki, Kohji ^a  

^a SAGA UNIVERSITY   (Japan)

Author keywords

E cadherin; Mts1; Quantitative PCR; Transfection

Indexed keywords

CALVASCULIN; GENE PRODUCT; MESSENGER RNA; UNCLASSIFIED DRUG; UVOMORULIN;

ARTICLE; CANCER INVASION; CARCINOMA CELL; CELL ADHESION; CELL MOTILITY; CELL POLARITY; CELL PROLIFERATION; CONTROLLED STUDY; GALLBLADDER CARCINOMA; GENE EXPRESSION; GENE LOSS; GENE REPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; METASTASIS; ONCOGENE C MYC; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AGED; CADHERINS; CARCINOMA; CARCINOMA, PAPILLARY; CELL ADHESION; CELL DIVISION; CELL MOVEMENT; COLLAGEN; DRUG COMBINATIONS; FEMALE; GALLBLADDER NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LAMININ; LIFE TABLES; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM PROTEINS; PROTEOGLYCANS; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM; S100 PROTEINS; SURVIVAL ANALYSIS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0037430147     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/ijc.10920     Document Type: Article

References (61)

1. Takeichi M. Morphogenetic roles of classic cadherins. Curr Opin Cell Biol 1995;7:619-27.
2. Katagiri A, Watanabe R, Tomita Y. E-cadherin expression in renal cell cancer and its significance in metastasis and survival. Br J Cancer 1995;71:376-9.
3. Heimann R, Lan F, McBride R, Hellman S. Separating favorable from unfavorable prognostic markers in breast cancer: the role of E-cadherin. Cancer Res 2000;60:298-304.
4. Zheng Z, Pan J, Chu B, Wong YC, Cheung AL, Tsao SW. Down-regulation and abnormal expression of E-cadherin and beta-catenin in nasopharyngeal carcinoma: close association with advanced disease stage and lymph node metastasis. Hum Pathol 1999;30:458-66.
5. Garcia del Muro X, Torregrosa A, Munoz J, Castellsague X, Condom E, Vigues F, Arance A, Fabra A, Germa JR. Prognostic value of the expression of E-cadherin and beta-catenin in bladder cancer. Eur J Cancer 2000;36:357-62.
6. Mori M, Miyazaki K, Kitahara K, Mukai S, Motoyama K, Edakuni G. Relationship between prognosis of gallbladder carcinoma patients and the expression of E-cadherin/alpha-catenin. Jpn J Gastroenterol Surg 2000;33:584-9.
7. Hermiston ML, Gordon JI. Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science 1995; 270:1203-7.
8. Guilford P, Hopkins J, Harraway J, McLeod M, McLeod N, Harawira P, Take H, Scoular R, Miller A, Reeve AE. E-cadherin germline mutations in familial gastric cancer. Nature 1998;392:402-5.
9. Gayther SA, Gorringe KL, Ramus SJ, Huntsman D, Roviello F, Grehan N, Machado JC, Pinto E, Seruca R, Halling K, MacLeod P, Powell SM, et al. Identification of germ-line E-cadherin mutations in gastric cancer families of European origin. Cancer Res 1998;58: 4086-9.
10. KIPI. J Cell Biol 1998;142:557-71.
11. Miyaki M, Tanaka K, Kikuchi-Yanoshita R, Muraoka M, Konishi M, Takeichi M. Increased cell-substratum adhesion, and decreased gelatinase secretion and cell growth, induced by E-cadherin transfection of human colon carcinoma cells. Oncogene 1995;11:2547-52.
12. Zhu AJ, Watt FM. Expression of a dominant negative cadherin mutant inhibits proliferation and stimulates terminal differentiation of human epidermal keratinocytes. J Cell Sci 1996;109:3013-23.
13. Vleminckx K, Vakaet L Jr, Mareel M, Fiers W, van Roy F. Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role. Cell 1991;66:107-19.
14. Perl AK, Wilgenbus P, Dahl U, Semb H, Christofori G. A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 1998;392:190-3.
15. Cubertafond P. Radical surgery for gallbladder cancer. Results of the French Surgical Association Survey. Hepatogastroenterology 1999; 46:1567-71.
16. Donohue JH. The National Cancer Data Base report on carcinoma of the gallbladder, 1989-1995. Cancer 1998;83:2618-28.
17. Hanada K, Itoh M, Fujii K, Tsuchida A, Ooishi H, Kajiyama G. K-ras and p53 mutations in stage I gallbladder carcinoma with an anomalous junction of the pancreaticobiliary duct. Cancer 1996;77:452-8.
18. Itoi T, Watanabe H, Ajioka Y, Oohashi Y, Takel K, Nishikura K, Nakamura Y, Horil A, Saito T. APC, K-ras codon 12 mutations and p53 gene expression in carcinoma and adenoma of the gall-bladder suggest two genetic pathways in gall-bladder carcinogenesis. Pathol Int 1996;46:333-40.
19. Sasatomi E, Tokunaga O, Miyazaki K. Precancerous conditions of gallbladder carcinoma: overview of histopathologic characteristics and molecular genetic findings. J Hepatobiliary Pancreat Surg 2000; 7:556-67.
20. Ajiki T, Onoyama H, Yamamoto M, Asaka K, Fujimori T, Maeda S, Saitoh Y. p53 protein expression and prognosis in gallbladder carcinoma and premalignant lesions. Hepatogastroenterology 1996;43:521-6.
21. Ink4B/MTS2 genes in biliary tract cancers. Cancer Res 1995;55: 2756-60.
22. Wistuba II, Albores-Saavedra J. Genetic abnormalities involved in the pathogenesis of gallbladder carcinoma. J Hepatobiliary Pancreat Surg 1999;6:237-44.
23. Mori M, Miyazaki K. Factors affecting morphogenesis of rabbit gallbladder epithelial cells cultured in collagen gels. Cell Tissue Res 2000;300:331-44.
24. Mukai S, Miyazaki K, Yakushiji H. The role of E-cadherin in the differentiation of gallbladder cancer cells. Cell Tissue Res 2001;306: 117-28.
25. Jiao W, Miyazaki K, Kitajima Y. Exogenous expression of E-cadherin in gallbladder carcinoma cell line G-415 restores its cellular polarity and differentiation. Int J Oncol 2001;19:1099-107.
26. Koyama S, Yoshioka T, Mizushima A, Kawakita I, Yamagata S, Fukutomi H, Sakita T, Kondo I, Kikuchi M. Establishment of a cell line (G-415) from a human gallbladder carcinoma. Jpn J Cancer Res 1980;71:574-5.
27. Shimura H, Date K, Matsumoto K, Nakamura T, Tanaka M. Induction of invasive growth in a gallbladder cancer cell line by hepatocyte growth factor in vitro. Jpn J Cancer Res 1995;86:662-9.
28. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983;65:55-63.
29. Tamura M, Gu J, Matsumoto K, Aota S, Parsons R, Yamada KM. Inhibition of cell migration, spreading, and focal adhesions by tumor suppressor PTEN. Science 1998;280:1614-7.
30. Ohsako T, Takao S, Uemura K, Imamura H, Aikou T. The invasion-MTT assay as a predictor of liver metastasis using human gastrointestinal carcinomas transplanted in nude mice. Surg Today 1997;27: 638-44.
31. Nose A, Nagafuchi A, Takeichi M. Expressed recombinant cadherins mediate cell sorting in model systems. Cell 1988;54:993-1001.
32. Navarro P, Gomez M, Pizarro A, Gamallo C, Quintanilla M, Cano A. A role for the E-cadherin cell-cell adhesion molecule during tumor progression of mouse epidermal carcinogenesis. J Cell Biol 1991;115: 517-33.
33. Frixen UH, Behrens J, Sachs M, Eberle G, Voss B, Warda A, Lochner D, Birchmeier W. E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. J Cell Biol 1991;113:173-85.
34. Fagotto F, Funayama N, Gluck U, Gumbiner BM. Binding to cadherins antagonizes the signaling activity of beta-catenin during axis formation in Xenopus. J Cell Biol 1996;132:1105-14.
35. Efstathiou JA, Liu D, Wheeler JM, Kim HC, Beck NE, Ilyas M, Karayiannakis AJ, Mortensen NJ, Kmiot W, Playford RJ, Pignatelli M, Bodmer WF. Mutated epithelial cadherin is associated with increased tumorigenicity and loss of adhesion and of responsiveness to the motogenic trefoil factor 2 in colon carcinoma cells. Proc Natl Acad Sci USA 1999;96:2316-21.
36. Yokota J. Tumor progression and metastasis. Carcinogenesis 2000; 21:497-503.
37. Collins K, Jacks T, Pavletich NP. The cell cycle and cancer. Proc Natl Acad Sci USA 1997;94:2776-8.
38. Rosen EM, Goldberg ID. Regulation of angiogenesis by scatter factor. EXS 1997;79:193-208.
39. Grigorian MS, Tulchinsky EM, Zain S, Ebralidze AK, Kramerov DA, Kriajevska MV, Georgiev GP, Lukanidin EM. The mts1 gene and control of tumor metastasis. Gene 1993;135:229-38.
40. Evers EE, Zondag GC, Malliri A, Price LS, ten Klooster JP, van der Kammen RA, Collard JG. Rho family proteins in cell adhesion and cell migration. Eur J Cancer 2000;36:1269-74.
41. Freije JM, MacDonald NJ, Steeg PS. Nm23 and tumour metastasis: basic and translational advances. Biochem Soc Symp 1998;63:261- 71.
42. Zetter BR. Adhesion molecules in tumor metastasis. Semin Cancer Biol 1993;4:219-29.
43. Stamenkovic I. Matrix metalloproteinases in tumor invasion and metastasis. Semin Cancer Biol 2000;10:415-33.
44. Curran S, Murray GI. Matrix metalloproteinases: molecular aspects of their roles in tumour invasion and metastasis. Eur J Cancer 2000;36: 1621-30.
45. Duffy MJ, Maguire TM, McDermott EW, O'Higgins N. Urokinase plasminogen activator: a prognostic marker in multiple types of cancer. J Surg Oncol 1999;71:130-5.
46. 2+-binding protein family. Genes Dev 1989;3:1086-93.
47. Lukanidin EM, Georgiev GP. Metastasis-related mts1 gene. Curr Top Microbiol Immunol 1996;213:171-95.
48. Parker C, Whittaker PA, Usmani BA, Lakshmi MS, Sherbet GV. Induction of 18A2/mts1 gene expression and its effects on metastasis and cell cycle control. DNA Cell Biol 1994;13:1021-8.
49. Selinfreund RH, Barger SW, Welsh MJ, Van Eldik LJ. Antisense inhibition of glial S100 beta production results in alterations in cell morphology, cytoskeletal organization, and cell proliferation. J Cell Biol 1990;111:2021-8.
50. Takenaga K, Nakamura Y, Sakiyama S, Hasegawa Y, Sato K, Endo H. Binding of pEL98 protein, an S100-related calcium-binding protein, to nonmuscle tropomyosin. J Cell Biol 1994;124:757-68.
51. Watanabe Y, Usada N, Minami H, Morita T, Tsugane S, Ishikawa R, Kohama K, Tomida Y, Hidaka H. Calvasculin, as a factor affecting the microfilament assemblies in rat fibroblasts transfected by src gene. FEBS Lett 1993;324:51-5.
52. Davies BR, Davies MP, Gibbs FE, Barraclough R, Rudland PS. Induction of the metastatic phenotype by transfection of a benign rat mammary epithelial cell line with the gene for p9Ka, a rat calcium-binding protein, but not with the oncogene EJ-ras-1. Oncogene 1993; 8:999-1008.
53. Keirsebilck A, Bonne S, Bruyneel E, Vermassen P, Lukanidin E, Mareel M, van Roy F. E-cadherin and metastasin (mts-1/S100A4) expression levels are inversely regulated in two tumor cell families. Cancer Res 1998;58:4587-91.
54. Kimura K, Endo Y, Yonemura Y, Heizmann CW, Schafer BW, Watanabe Y, Sasaki T. Clinical significance of S100A4 and E-cadherin-related adhesion molecules in non-small cell lung cancer. Int J Oncol 2000;16:1125-31.
55. Yonemura Y, Endou Y, Kimura K, Fushida S, Bandou E, Taniguchi K, Kinoshita K, Ninomiya I, Sugiyama K, Heizmann CW, Schafer BW, Sasaki T. Inverse expression of S100A4 and E-cadherin is associated with metastatic potential in gastric cancer. Clin Cancer Res 2000;6:4234-42.
56. Orsulic S, Huber O, Aberle H, Arnold S, Kemler R. E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation. J Cell Sci 1999;112:1237-45.
57. Torres MA, Yang-Snyder JA, Purcell SM, DeMarais AA, McGrew LL, Moon RT. Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development. J Cell Biol 1996; 133:1123-37.
58. Sanson B, White P, Vincent JP. Uncoupling cadherin-based adhesion from wingless signalling in Drosophila. Nature 1996;383:627-30.
59. He TC, Sparks AB, Rago C, Hermeking H, Zawel L, da Costa LT, Morin PJ, Vogelstein B, Kinzler KW. Identification of c-MYC as a target of the APC pathway. Science 1998;281:1509-12.
60. Ara T, Deyama Y, Yoshimura Y, Higashino F, Shindoh M, Matsumoto A, Fukuda H. Membrane type 1-matrix metalloproteinase expression is regulated by E-cadherin through the suppression of mitogen-activated protein kinase cascade. Cancer Lett 2000;157:115-21.
61. Llorens A, Rodrigo I, Lopez-Barcons L, Gonzalez-Garrigues M, Lozano E, Vinyals A, Quintanilla M, Cano A, Fabra A. Down-regulation of E-cadherin in mouse skin carcinoma cells enhances a migratory and invasive phenotype linked to matrix metalloproteinase-9 gelatinase expression. Lab Invest 1998;78:1131-42.