Noninvasive estimation of tumour viability in a xenograft model of human neuroblastoma with proton magnetic resonance spectroscopy (1H MRS)

British Journal of Cancer

Volumn 88, Issue 3, 2003, Pages 478-485

  Lindskog, M ^a   Kogner, P ^a   Ponthan, F ^a   Schweinhardt, P ^b   Sandstedt, B ^a   Heiden, T ^c   Helms, G ^b   Spenger, C ^b  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c HUMBOLDT UNIVERSITY   (Germany)

Author keywords

Angiogenesis; MRI; Neuroblastoma; Spectroscopy; Therapy; Xenograft

Indexed keywords

ANGIOGENESIS INHIBITOR; CHOLINE; FUMAGILLOL CHLOROACETYLCARBAMATE; HYDROGEN; LIPID;

ACCURACY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; MALE; METABOLISM; NEUROBLASTOMA; NON INVASIVE MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; RAT STRAIN; SPECTROSCOPY; TUMOR MODEL; TUMOR VOLUME; XENOGRAFT;

ANGIOGENESIS INHIBITORS; ANIMALS; CELL SURVIVAL; DISEASE MODELS, ANIMAL; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEOPLASM TRANSPLANTATION; NEOPLASMS, EXPERIMENTAL; NEUROBLASTOMA; PROTONS; RATS; RATS, NUDE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 0037428775     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjc.6600704     Document Type: Article

References (47)

1. Ackerstaff E, Pflug BR, Nelson JB, Bhujwalla ZM (2001) Detection of increased choline compounds with proton nuclear magnetic resonance spectroscopy subsequent to malignant transformation of human prostatic epithelial cells. Cancer Res 61: 3599-3603
2. Barba I, Cabanas ME, Arus C (1999) The relationship between nuclear magnetic resonance-visible lipids, lipid droplets, and cell proliferation in cultured C6 cells. Cancer Res 59: 1861-1868
3. Berdon WE, Ruzal-Shapiro C, Abramson SJ, Garvin J (1992) The diagnosis of abdominal neuroblastoma: relative roles of ultrasonography, CT, and MRI. Urol Radiol 14: 252-262
4. Bezabeh T, Mowat MR, Jarolim L, Greenberg AH, Smith IC (2001) Detection of drug-induced apoptosis and necrosis in human cervical carcinoma cells using (1)H NMR spectroscopy. Cell Death Differ 8: 219-224
5. Bhakoo KK, Williams SR, Florian CL, Land H, Noble MD, The Royal College of Surgeons Unit of Biophysics, I.o.C.H., London, United Kingdom (1996) Immortalization and transformation are associated with specific alterations in choline metabolism. Cancer Res 56(20): 4630-4635
6. Biedler JL, Helson L, Spengler BA (1973) Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture. Cancer Res 33: 2643-2652
7. Bjornsson J, Inwards CY, Wold LE, Sim FH, Taylor WF (1993) Prognostic significance of spontaneous tumour necrosis in osteosarcoma. Virchows Arch A Pathol Anat Histopathol 423: 195-199
8. Blankenberg FG, Katsikis PD, Storrs RW, Beaulieu C, Spielman D, Chen JY, Naumovski L, Tait JF (1997) Quantitative analysis of apoptotic cell death using proton nuclear magnetic resonance spectroscopy. Blood 89: 3778-3786
9. Bown N, Cotterill S, Lastowska M, O'Neill S, Pearson AD, Plantaz D, Meddeb M, Danglot G, Brinkschmidt C, Christiansen H, Laureys G, Speleman F (1999) Gain of chromosome arm 17q and adverse outcome in patients with neuroblastoma. N Engl J Med 340: 1954-1961
10. Caron H, van Sluis P, de Kraker J, Bokkerink J, Egeler M, Laureys G, Slater R, Westerveld A, Voute PA, Versteeg R (1996) Allelic loss of chromosome lp as a predictor of unfavorable outcome in patients with neuroblastoma. N Engl J Med 334: 225-230
11. Castronovo V, Belotti D (1996) TNP-470 (AGM-1470): mechanisms of action and early clinical development. Eur J Cancer 32A: 2520-2527
12. de Certaines JD (1996) High resolution nuclear magnetic resonance spectroscopy in clinical biology: application in oncology. Anticancer Res 16: 1325-1331
13. Evtouchenko L, Studer L, Spenger C, Dreher E, Seller RW (1996) A mathematical model for the estimation of human embryonic and fetal age. Cell Transplant 5: 453-464
14. Finelli A, Babyn P, Lorie GA, Bagli D, Khoury AE, Merguerian PA (2000) The use of magnetic resonance imaging in the diagnosis and followup of pediatric pelvic rhabdomyosarcoma. J Urol 163: 1952-1953
15. Florian CL, Preece NE, Bhakoo KK, Williams SR, Noble M (1995) Characteristic metabolic profiles revealed by 1 H NMR spectroscopy for three types of human brain and nervous system tumours. NMR Biomed 8: 253-264
16. Gavrieli Y, Sherman Y, Ben-Sasson SA (1992) Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 119: 493-501
17. Guidoni L, Mariutti G, Rampelli GM, Rosi A, Viti V (1987) Mobile phospholipid signals in NMR spectra of cultured human adenocarcinoma cells. Magn Reson Med 5: 578-585
18. Gyngell ML, Els T, Hoehn-Berlage M, Hossmann KA (1994) Proton MR spectroscopy of experimental brain tumors in vivo. Acta Neurochir (Suppl) 60: 350-352
19. Hakumaki JM, Grohn OH, Tyynela K, Valonen P, Yla-Herttuala S, Kauppinen RA (2002) Early gene therapy-induced apoptotic response in BT4C gliomas by magnetic resonance relaxation contrast T(1) in the rotating frame. Cancer Gene Ther 9: 338-345
20. Hiorns MP, Owens CM (2001) Radiology of neuroblastoma in children. Eur Radiol 11: 2071-2081
21. Howe FA, Maxwell RJ, Saunders DE, Brown MM, Griffiths JR (1993) Proton spectroscopy in vivo. Magn Reson Q 9: 31-59
22. Jakobsen IKO, Lyng H, Rofstad EK, Institute for Cancer Research, N.R.H., Montebello Oslo (1995) Detection of necrosis in human tumour xenografts by proton magnetic resonance imaging. Br J Cancer 71(3): 456-461
23. Katzenstein HM, Rademaker AW, Senger C, Salwen HR, Nguyen NN, Thorner PS, Litsas L, Cohn SL (1999) Effectiveness of the angiogenesis inhibitor TNP-470 in reducing the growth of human neuroblastoma in nude mice inversely correlates with tumor burden. Clin Cancer Res 5: 4273-4278
24. Kauppinen RA (2002) Monitoring cytotoxic tumour treatment response by diffusion magnetic resonance imaging and proton spectroscopy. NMR Biomed 15: 6-17
25. Kuesel AC, Briere KM, Halliday WC, Sutherland GR, Donnelly SM, Smith IC (1996) Mobile lipid accumulation in necrotic tissue of high grade astrocytomas. Anticancer Res 16: 1485-1489
26. Kuesel AC, Sutherland GR, Halliday W, Smith IC (1994) 1 H MRS of high grade astrocytomas: mobile lipid accumulation in necrotic tissue. NMR Biomed 7: 149-155
27. Le Moyec L, Tatoud R, Eugene M, Gauville C, Primot I, Charlemagne D, Calvo F (1992) Cell and membrane lipid analysis by proton magnetic resonance spectroscopy in five breast cancer cell lines. Br J Cancer 66: 623-628
28. Matthay KK, Villablanca JG, Seeger RC, Stram DO, Harris RE, Ramsay NK, Swift P, Shimada H, Black CT, Brodeur GM, Gerbing RB, Reynolds CP (1999) Treatment of high-risk neuroblastoma with intensive chemotherapy, radiotherapy, autologous bone marrow transplantation, and 13-cis-retinoic acid Children's Cancer Group. N Engl J Med 341: 1165-1173
29. Negendank W (1992) Studies of human tumors by MRS: a review. NMR Biomed 5: 303-324
30. Negendank W and Sauter R (1996) Intratumoral lipids in 1 H MRS in vivo in brain tumors: experience of the Siemens cooperative clinical trial. Anticancer Res 16: 1533-1538
31. Negendank WG, Sauter R, Brown TR, Evelhoch JL, Falini A, Gotsis ED, Heerschap A, Kamada K, Lee BC, Mengeot MM, Moser E, Padavic-Shaller KA, Sanders JA, Spraggins TA, Stillman AE, Terwey B, Vogl TJ, Wicklow K, Zimmerman RA (1996) Proton magnetic resonance spectroscopy in patients with glial tumors: a multicenter study. J Neurosurg 84: 449-458
32. Nilsson S, Pahlman S, Arnberg H, Letocha H, Westlin JE (1993) Characterisation and uptake of radiolabelled meta-iodobenzylguanidine (MIBG) in a human neuroblastoma heterotransplant model in athymic rats. Acta Oncol 32: 887-891
33. Pierallini A, Bonamini M, Pantano P, Palmeggiani F, Raguso M, Osti MF, Anaveri G, Bozzao L (1998) Radiological assessment of necrosis in glioblastoma: variability and prognostic value. Neuroradiology 40: 150-153
34. Ponthan F, Borgstrom P, Hassan M, Wassberg E, Redfern CP, Kogner P (2001) The vitamin A analogues: 13-cis retinoic acid, 9-cis retinoic acid, and Ro 13-6307 inhibit neuroblastoma tumour growth in vivo. Med Pediatr Oncol 36: 127-131
35. Seeger RC, Brodeur GM, Sather H, Dalton A, Siegel SE, Wong KY, Hammond D (1985) Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N Engl J Med 313: 1111-1116
36. Shapeero LG, Vanel D (2000) Imaging evaluation of the response of high-grade osteosarcoma and Ewing sarcoma to chemotherapy with emphasis on dynamic contrast-enhanced magnetic resonance imaging. Semin Musculoskelet Radiol 4: 137-146
37. Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B (1999a) Terminology and morphologic criteria of neuroblastic tumors: recommendations by the International Neuroblastoma Pathology Committee. Cancer 86: 349-363
38. Shimada H, Ambros IM, Dehner LP, Hata J, Joshi VV, Roald B, Stram DO, Gerbing RB, Lukens JN, Matthay KK, Castleberry RP (1999b) The International Neuroblastoma Pathology Classification (the Shimada system). Cancer 86: 364-372
39. Siegel MJ, Ishwaran H, Fletcher BD, Meyer JS, Hoffer FA, Jaramillo D, Hernandez RJ, Roubal SE, Siegel BA, Caudry DJ, McNeil BJ (2002) Staging of neuroblastoma at imaging: report of the radiology diagnostic oncology group. Radiology 223: 168-175
40. Smith TA, Eccles S, Ormerod MG, Tombs AJ, Titley JC, Leach MO (1991) The phosphocholine and glycerophosphocholine content of an oestrogen-sensitive rat mammary tumour correlates strongly with growth rate. Br J Cancer 64: 821-826
41. Tamiya T, Kinoshita K, Ono Y, Matsumoto K, Furuta T, Ohmoto T (2000) Proton magnetic resonance spectroscopy reflects cellular proliferative activity in astrocytomas. Neuroradiology 42: 333-338
42. Tedeschi G, Lundbom N, Raman R, Bonavita S, Duyn JH, Alger IR, Di Chiro G (1997) Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging study. J Neurosurg 87: 516-524
43. Urenjak J, Williams SR, Gadian DG, Noble M (1992) Specific expression of N-acetylaspartate in neurons, oligodendrocyte- type-2 astrocyte progenitors, and immature oligodendrocytes in vitro. J Neurochem 59: 55-61
44. Usenius JP, Vainio P, Hernesniemi J, Kauppinen RA (1994) Choline-containing compounds in human astrocytomas studied by 1 H NMR spectroscopy in vivo and in vitro. J Neurochem 63: 1538-1543
45. Wassberg E, Pahlman S, Westlin JE, Christofferson R (1997) The angiogenesis inhibitor TNP-470 reduces the growth rate of human neuroblastoma in nude rats. Pediatr Res 41: 327-333
46. Veale MF, Roberts NJ, King GF, King NJ (1997) The generation of 1H-NMR-detectable mobile lipid in stimulated lymphocytes: relationship to cellular activation, the cell cycle, and phosphatidylcholine-specific phospholipase C. Biochem Biophys Res Commun 239: 868-874
47. United Kingdom Co-ordinating Committee on Cancer Research (UKCCCR) (1998) Guidelines for the Welfare of Animals in Experimental Neoplasia (Second Edition). Br J Cancer 77: 1-10