Human IL-21 and IL-4 bind to partially overlapping epitopes of common γ-chain

Biochemical and Biophysical Research Communications

Volumn 300, Issue 2, 2003, Pages 291-296

  Zhang, Jin Li ^a   Foster, Don ^b   Sebald, Walter ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b ZYMOGENETICS INC   (United States)

Author keywords

Common chain; Interleukin 21; Interleukin 21 receptor; Interleukin 4; Mutagenesis; Protein protein interaction; Structure function

Indexed keywords

ALANINE; EPITOPE; INTERLEUKIN 21; INTERLEUKIN 4; INTERLEUKIN RECEPTOR; LIGAND; RECOMBINANT CYTOKINE; IL21R PROTEIN, HUMAN; IL2RG PROTEIN, HUMAN; INTERLEUKIN 2 RECEPTOR GAMMA; INTERLEUKIN 21 RECEPTOR; INTERLEUKIN 21 RECEPTOR ALPHA; INTERLEUKIN 7 RECEPTOR; INTERLEUKIN DERIVATIVE;

ARTICLE; BIOSENSOR; COMPLEX FORMATION; HUMAN; LIGAND BINDING; MOLECULAR BIOLOGY; MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN IMMOBILIZATION; PROTEIN STRUCTURE; AMINO ACID SEQUENCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; MACROMOLECULE; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; BINDING SITES; EPITOPES; HUMANS; INTERLEUKIN RECEPTOR COMMON GAMMA SUBUNIT; INTERLEUKIN-21 RECEPTOR ALPHA SUBUNIT; INTERLEUKIN-4; INTERLEUKINS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-21; RECEPTORS, INTERLEUKIN-7; SEQUENCE ALIGNMENT;

EID: 0037427517     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(02)02836-X     Document Type: Article

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