Intracellular localization of the p35 subunit of murine IL-12

Cytokine

Volumn 21, Issue 3, 2003, Pages 120-128

  Vaidyanathan, Hema ^a   Zhou, You ^a   Petro, Thomas M ^b   Schwartzbach, Steven D ^a,c  

^a UNIVERSITY OF NEBRASKA LINCOLN   (United States)

^b UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^c UNIVERSITY OF MEMPHIS   (United States)

Author keywords

Cytokine; Glycosylation; Macrophage; Membrane

Indexed keywords

COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; INTERLEUKIN 12; MESSENGER RNA; PROTEIN P35; PROTEIN P40; PROTEIN SUBUNIT; SIGNAL PEPTIDE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; CERCOPITHECIDAE; CODING; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOPLASMIC RETICULUM; GOLGI COMPLEX; IMMUNOBLOTTING; KIDNEY CELL; MICROSOME MEMBRANE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN LOCALIZATION;

CERCOPITHECUS AETHIOPS; MURINAE;

EID: 0037423074     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-4666(03)00016-4     Document Type: Article

References (41)

1. Trinchieri G. Immunobiology of interleukin-12. Immunol Res. 17:1998;269-278.
2. Manetti R., Parronchi P., Giudizi M.G., Piccinni M.P., Maggi E., Trinchieri G., et al. Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells. J Exp Med. 177:1993;1199-1204.
3. Hsieh C.S., Macatonia S.E., Tripp C.S., Wolf S.F., O'Garra A., Murphy K.M. Development of TH1 CD4+T cells through IL-12 produced by Listeria- induced macrophages. Science. 260:1993;547-549.
4. Podlaski F.J., Nanduri V.B., Hulmes J.D., Pan Y.C., Levin W., Danho W., et al. Molecular characterization of interleukin 12. Arch Biochem Biophys. 294:1992;230-237.
5. Tone Y., Thompson S.A., Babik J.M., Nolan K.F., Tone M., Raven C., et al. Structure and chromosomal location of the mouse interleukin-12 p35 and p40 subunit genes. Eur J Immunol. 26:1996;1222-1227.
6. Schoenhaut D.S., Chua A.O., Wolitzky A.G., Quinn P.M., Dwyer C.M., McComas W., et al. Cloning and expression of murine IL-12. J Immunol. 148:1992;3433-3440.
7. Bette M., Jin S.C., Germann T., Schafer M.K., Weihe E., Rude E., et al. Differential expression of mRNA encoding interleukin-12 p35 and p40 subunits in situ. Eur J Immunol. 24:1994;2435-2440.
8. D'Andrea A., Rengaraju M., Valiante N.M., Chehimi J., Kubin M., Aste M., et al. Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. J Exp Med. 176:1992;1387-1398.
9. Ling P., Gately M.K., Gubler U., Stern A.S., Lin P., Hollfelder K., et al. Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity. J Immunol. 154:1995;116-127.
10. Gillessen S., Carvajal D., Ling P., Podlaski F.J., Stremlo D.L., Familletti P.C., et al. Mouse interleukin-12 (IL-12) p40 homodimer: a potent IL-12 antagonist. Eur J Immunol. 25:1995;200-206.
11. Snijders A., Hilkens C.M., van der Pouw Kraan T.C., Engel M., Aarden L.A., Kapsenberg M.L. Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit. J Immunol. 156:1996;1207-1212.
12. Babik J.M., Adams E., Tone Y., Fairchild P.J., Tone M., Waldmann H. Expression of murine IL-12 is regulated by translational control of the p35 subunit. J Immunol. 162:1999;4069-4078.
13. Hayes M.P., Murphy F.J., Burd P.R. Interferon-gamma-dependent inducible expression of the human interleukin-12 p35 gene in monocytes initiates from a TATA-containing promoter distinct from the CpG-rich promoter active in Epstein-Barr virus-transformed lymphoblastoid cells. Blood. 91:1998;4645-4651.
14. Vaidyanathan H., Gentry J.D., Weatherman A., Schwartzbach S.D., Petro T.M. Differential response of the murine IL-12 p35 gene to lipopolysaccharide compared with interferon-gamma and CD40 ligation. Cytokine. 16:2001;1-9.
15. Fan X., Sibalic V., Niederer E., Wuthrich R.P. The proinflammatory cytokine interleukin-12 occurs as a cell membrane-bound form on macrophages. Biochem Biophys Res Commun. 225:1996;1063-1067.
16. Quinones M., Ahuja S.K., Melby P.C., Pate L., Reddick R.L., Ahuja S.S. Preformed membrane-associated stores of interleukin (IL)-12 are a previously unrecognized source of bioactive IL-12 that is mobilized within minutes of contact with an intracellular parasite. J Exp Med. 192:2000;507-516.
17. Bliss S.K., Butcher B.A., Denkers E.Y. Rapid recruitment of neutrophils containing prestored IL-12 during microbial infection. J Immunol. 165:2000;4515-4521.
18. Murphy F.J., Hayes M.P., Burd P.R. Disparate intracellular processing of human IL-12 preprotein subunits: atypical processing of the P35 signal peptide. J Immunol. 164:2000;839-847.
19. Carra G., Gerosa F., Trinchieri G. Biosynthesis and posttranslational regulation of human IL-12. J Immunol. 164:2000;4752-4761.
20. Kobayashi M., Fitz L., Ryan M., Hewick R.M., Clark S.C., Chan S., et al. Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes. J Exp Med. 170:1989;827-845.
21. Heinzel F.P., Hujer A.M., Ahmed F.N., Rerko R.M. In vivo production and function of IL-12 p40 homodimers. J Immunol. 158:1997;4381-4388.
22. Yoshimoto T., Wang C.R., Yoneto T., Waki S., Sunaga S., Komagata Y., et al. Reduced T helper 1 responses in IL-12 p40 transgenic mice. J Immunol. 160:1998;588-594.
23. Walter P., Johnson A.E. Signal sequence recognition and protein targeting to the endoplasmic reticulum membrane. Annu Rev Cell Biol. 10:1994;87-119.
24. High S., Dobberstein B. Mechanisms that determine the transmembrane disposition of proteins. Curr Opin Cell Biol. 4:1992;581-586.
25. Fujiki Y., Hubbard A.L., Fowler S., Lazarow P.B. Isolation of intracellular membranes by means of sodium carbonate treatment: application to endoplasmic reticulum. J Cell Biol. 93:1982;97-102.
26. Shaw A.S., Rottier P.J., Rose J.K. Evidence for the loop model of signal-sequence insertion into the endoplasmic reticulum. Proc Natl Acad Sci USA. 85:1988;7592-7596.
27. Schlondorff J., Blobel C.P. Metalloprotease-disintegrins: modular proteins capable of promoting cell-cell interactions and triggering signals by protein-ectodomain shedding. J Cell Sci. 112:1999;3603-3617.
28. Black R.A., Rauch C.T., Kozlosky C.J., Peschon J.J., Slack J.L., Wolfson M.F. A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature. 385:1997;729-733.
29. Schlondorff J., Becherer J.D., Blobel C.P. Intracellular maturation and localization of the tumour necrosis factor alpha convertase (TACE). Biochem J. 347:2000;131-138.
30. Peschon J.J., Slack J.L., Reddy P., Stocking K.L., Sunnarborg S.W., Lee D.C. An essential role for ectodomain shedding in mammalian development. Science. 282:1998;1281-1284.
31. Croucher P.I., Wang F., Hargreaves P.G. Interleukin-6 receptor shedding: a possible role for members of the ADAM family. Biochem Soc Trans. 27:1999;224-228.
32. Dallas D.J., Genever P.G., Patton A.J., Millichip M.I., McKie N., Skerry T.M. Localization of ADAM10 and Notch receptors in bone. Bone. 25:1999;9-15.
33. Howard L., Maciewicz R.A., Blobel C.P. Cloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28. Biochem J. 348:2000;21-27.
34. Hougaard S., Loechel F., Xu X., Tajima R., Albrechtsen R., Wewer U.M. Trafficking of human ADAM 12-L: retention in the trans-Golgi network. Biochem Biophys Res Commun. 275:2000;261-267.
35. Lum L., Reid M.S., Blobel C.P. Intracellular maturation of the mouse metalloprotease disintegrin MDC15. J Biol Chem. 273:1998;26236-26247.
36. Skovronsky D.M., Moore D.B., Milla M.E., Doms R.W., Lee V.M. Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans Golgi network. J Biol Chem. 275:2000;2568-2575.
37. Bosenberg M.W., Pandiella A., Massague J. The cytoplasmic carboxy-terminal amino acid specifies cleavage of membrane TGF alpha into soluble growth factor. Cell. 71:1992;1157-1165.
38. Zhang T., Wong S.H., Tang B.L., Xu Y., Hong W. Morphological and functional association of Sec22b/ERS-24 with the pre-Golgi intermediate compartment. Mol Biol Cell. 10:1999;435-453.
39. Tarasova N.I., Stauber R.H., Michejda C.J. Spontaneous and ligand-induced trafficking of CXC-chemokine receptor 4. J Biol Chem. 273:1998;15883-15886.
40. Kang H.S., Welch W.J. Characterization and purification of the 94-kDa glucose-regulated protein. J Biol Chem. 266:1991;5643-5649.
41. Chewawiwat N., Yano M., Terada K., Hoogenraad N.J., Mori M. Characterization of the novel mitochondrial protein import component, Tom34, in mammalian cells. J Biochem (Tokyo). 125:1999;721-727.