Decreased efficiency of adenovirus-mediated gene transfer in aging cardiomyocytes

Circulation

Volumn 107, Issue 8, 2003, Pages 1170-1175

  Communal, Catherine ^b   Huq, Fawzia ^a   Lebeche, Djamel ^a   Mestel, Celine ^a   Gwathmey, Judith K ^a   Hajjar, Roger J ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HÔPITAL LARIBOISIÈRE   (France)

Author keywords

Aging; Gene therapy; Myocytes; Receptors; Viruses

Indexed keywords

ADENOVIRUS VECTOR; BETA GALACTOSIDASE; GREEN FLUORESCENT PROTEIN; LAMININ; VIRUS RECEPTOR;

ADOLESCENT; AGED; ANIMAL CELL; ARTICLE; CELL AGING; CONTROLLED STUDY; CYTOMEGALOVIRUS; GENE TRANSFER; HEART CELL CULTURE; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; SARCOLEMMA; VIRUS INFECTIVITY;

ADENOVIRIDAE; AGING; ANIMALS; CELLS, CULTURED; GENETIC VECTORS; INTEGRINS; MALE; MYOCYTES, CARDIAC; RATS; RATS, INBRED F344; RECEPTORS, VIRUS; TRANSDUCTION, GENETIC;

EID: 0037418226     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000051467.31874.29     Document Type: Article

References (21)

1. Lakatta EG, Sollott SJ. Perspectives on mammalian cardiovascular aging: humans to molecules. Comp Biochem Physiol A Mol Integr Physiol. 2002;132:699-721.
2. Swynghedauw B, Besse S, Assayag P, et al. Molecular and cellular biology of the senescent hypertrophied and failing heart. Am J Cardiol. 1995;76:2D-7D.
3. Schmidt U, del Monte F, Miyamoto MI, et al. Restoration of diastolic function in senescent rat hearts through adenoviral gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase. Circulation. 2000;101: 790-796.
4. Communal C, Verdetti J, Estrade C, et al. Heterogeneous distribution of a fatty acid analogue uptake in the myocardium of aged rats. Can J Physiol Pharmacol. 1994;72:1120-1126.
5. Nitahara JA, Cheng W, Liu Y, et al. Intracellular calcium, DNase activity and myocyte apoptosis in aging Fischer 344 rats. J Mol Cell Cardiol. 1998;30:519-535.
6. Burgess ML, McCrea JC, Hedrick HL. Age-associated changes in cardiac matrix and integrins. Mech Ageing Dev. 2001;122:1739-1756.
7. Bergelson JM, Cunningham JA, Droguett G, et al. Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5. Science. 1997;275:1320-1323.
8. Hidaka C, Milano E, Leopold PL, et al. CAR-dependent, and CAR-independent pathways of adenovirus vector-mediated gene transfer and expression in human fibroblasts. J Clin. Invest. 1999;103:579-587.
9. 3 promote adenovirus internalization but not virus attachment. Cell. 1993; 73:309-319.
10. 1-mediated adenovirus infection is enhanced by the integrin-activating antibody TS2/16. J Virol. 1997;71:6204-6207.
11. Ruoslahti E. RGD and other recognition sequences for integrins. Annu Rev Cell Dev Biol. 1996;12:697-715.
12. Ito M, Kodama M, Masuko M, et al. Expression of coxsackievirus and adenovirus receptor in hearts of rats with experimental autoimmune myocarditis. Circ Res. 2000;86:275-280.
13. Ross RS, Borg TK. Integrins and the myocardium. Circ Res. 2001;88: 1112-1129.
14. Maitra N, Flink IL, Bahl JJ, et al. Expression of α and β integrins during terminal differentiation of cardiomyocytes. Cardiovasc Res. 2000;47: 715-725.
15. He TC, Zhou S, da Costa LT, et al. A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci USA. 1998;95: 2509-2514.
16. Communal C, Singh K, Pimentel DR, et al. Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. Circulation. 1998;98:1329-1334.
17. Cao B, Pruchnic R, Ikezawa M, et al. The role of receptors in the maturation-dependent adenoviral transduction of myofibers. Gene Ther. 2001;8:627-637.
18. 5 on the cardiomyocyte sarcolemma and upregulated in dilated cardiomyopathy: implications for cardiotropic viral infections. Circulation. 2001;104:275-280.
19. Liu PP, Opavsky MA. Viral myocarditis: receptors that bridge the cardiovascular with the immune system? Circ Res. 2000;86:253-254.
20. Cohen CJ, Shieh JT, Pickles RJ, et al. The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction. Proc Natl Acad Sci USA. 2001;98:15191-15196.
21. Severs NJ. Gap junction alterations in the failing heart. Eur Heart J. 1994;15(suppl D):53-57.