Increased susceptibility to LPS-induced endotoxin shock in secretory leukoprotease inhibitor (SLPI)-deficient mice

Journal of Experimental Medicine

Volumn 197, Issue 5, 2003, Pages 669-674

  Nakamura, Akira ^a   Mori, Yuriko ^a   Hagiwara, Koichi ^a   Suzuki, Takuji ^a   Sakakibara, Tomohiro ^a   Kikuchi, Toshiaki ^a   Igarashi, Takayuki ^a   Ebina, Masahito ^a   Abe, Tatsuya ^a   Miyazaki, Junichi ^c   Takai, Toshiyuki ^a,b   Nukiwa, Toshihiro ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

Author keywords

Endotoxin shock; Innate immunity; LPS; NF B; SLPI

Indexed keywords

HIGH MOBILITY GROUP B1 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN M; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BACTERIAL INFECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMORAL IMMUNITY; IMMUNOGLOBULIN PRODUCTION; INFLAMMATION; KNOCKOUT MOUSE; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPTIC SHOCK;

ANIMALS; B-LYMPHOCYTES; DISEASE SUSCEPTIBILITY; HMGB1 PROTEIN; I-KAPPA B PROTEINS; INTERLEUKIN-1; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NF-KAPPA B; NITRATES; PROTEINASE INHIBITORY PROTEINS, SECRETORY; PROTEINS; SECRETORY LEUKOCYTE PEPTIDASE INHIBITOR; SERINE PROTEINASE INHIBITORS; SHOCK, SEPTIC; SURVIVAL RATE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037416147     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021824     Document Type: Article

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