Synthesis of 5-(7-hydroxyhept-3-enyl)-1,2-dithiolan-3-one 1-oxide, a core functionality of antibiotic leinamycin

Tetrahedron

Volumn 59, Issue 6, 2003, Pages 833-839

  Lee, Alex H F ^a   Chan, Albert S C ^a   Li, Tianhu ^a  

^a HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

1,2 dithiolan 3 one 1 oxide; Activated ester; Antibiotic leinamycin; Antisense oligonucleotide; DNA cleaving agent; Heterocycle

Indexed keywords

5 (7 HYDROXYHEPT 3 ENYL) 1,2 DITHIOLAN 3 ONE 1 OXIDE; ANTIBIOTIC AGENT; ESTER DERIVATIVE; LEINAMYCIN; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CYCLIZATION; DRUG DNA BINDING; DRUG SYNTHESIS; OXIDATION; PRIORITY JOURNAL; SILYLATION;

EID: 0037415482     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4020(02)01600-9     Document Type: Article

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