메뉴 건너뛰기




Volumn 13, Issue 10, 2000, Pages 953-956

Mechanisms of DNA damage by leinamycin

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIN; DOUBLE STRANDED DNA; LEINAMYCIN; OXIDE; THIOL DERIVATIVE;

EID: 0033791629     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx000089m     Document Type: Conference Paper
Times cited : (83)

References (38)
  • 2
    • 0001216149 scopus 로고    scopus 로고
    • Covalent modification of DNA by natural products
    • Comprehensive Natural Products Chemistry (Barton, D. H. R., Nakanishi, K., and Meth-Cohn, O., Eds.) Pergamon, New York
    • (1999) , vol.7 , pp. 491-552
    • Gates, K.S.1
  • 15
    • 0029037105 scopus 로고
    • The reaction of n-propanethiol with 3H-1,2-benzodithiol-3-one 1-oxide and 5,5-dimethyl-1,2-dithiolan-3-one 1-oxide: Studies related to the reaction of antitumor antibiotic leinamycin with DNA
    • (1995) J. Org. Chem. , vol.69 , pp. 3964-3966
    • Behroozi, S.J.1    Kim, W.2    Gates, K.S.3
  • 17
    • 0031439957 scopus 로고    scopus 로고
    • Oxidative DNA cleavage by the antitumor antibiotic leinamycin and simple 1,2-dithiolan-3-one 1-oxides: Evidence for thiol-dependent conversion of molecular oxygen to DNA-cleaving oxygen radicals mediated by polysulfides
    • (1997) J. Am. Chem. Soc. , vol.119 , pp. 11691-11692
    • Mitra, K.1    Kim, W.2    Daniels, J.S.3    Gates, K.S.4
  • 20
    • 0015954510 scopus 로고
    • Generation of superoxide free radical during the autooxidation of thiols
    • (1974) J. Biol. Chem. , vol.249 , pp. 2151-2155
    • Misra, H.P.1
  • 38
    • 0026795880 scopus 로고
    • Depletion of a discrete nuclear gluathione pool by oxidative stress, but not by buthionine sulfoximine. Correlation with enhanced alkylating agent cytotoxicity to human melanoma cells in vitro
    • (1992) Biochem. Pharmacol. , vol.44 , pp. 1383-1393
    • Jevtovic-Todorovic, V.1    Guenthner, T.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.