Flagellar basal body flg operon as a virulence determinant of Vibrio vulnificus

Biochemical and Biophysical Research Communications

Volumn 304, Issue 2, 2003, Pages 405-410

  Kim, Young Ran ^a   Rhee, Joon Haeng ^a  

^a Chonnam National University Medical School   (South Korea)

Author keywords

Adhesion; Cytotoxicity; flg operon; Himar1; LD50; Motility; Vibrio vulnificus; Virulence

Indexed keywords

BACTERIAL PROTEIN; HEMOLYSIN; PROTEIN FLGC; PROTEINASE; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL FLAGELLUM; BACTERIAL GENE; BACTERIAL MUTATION; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; BACTERIUM MUTANT; BIOGENESIS; CONTROLLED STUDY; CYTOTOXICITY; FLG OPERON; GENE CLUSTER; GENE INSERTION; GENE LIBRARY; GENETIC SCREENING; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OPEN READING FRAME; OPERON; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; TRANSPOSON; VIBRIO PARAHAEMOLYTICUS; VIBRIO VULNIFICUS;

BACTERIA (MICROORGANISMS); EUKARYOTA; INSERTION SEQUENCES; TRANSPOSONS; VIBRIO; VIBRIO PARAHAEMOLYTICUS; VIBRIO VULNIFICUS;

EID: 0037414463     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-291X(03)00613-2     Document Type: Article

References (28)

1. Park S.D., Shon H.S., John N.J. Vibrio vulnificus septicemia in Korea: clinical and epidemiological findings in 70 patients. J. Am. Acad. Dermatol. 24:1991;397-403.
2. Paik K.W., Moon B., Park C.W., Kim K.T., Ji M.S., Choi S.K., Rew J.S., Yoon C.M. Clinical characteristics of ninety-two cases of Vibrio vulnificus infections. Kor. J. Infect. Dis. 27:1995;355-365.
3. Tacket C.O., Brenner F., Blake N.J. Clinical features and epidemiological study of Vibrio vulnificus infections. J. Infect. Dis. 149:1984;559-561.
4. Gray L.D., Kreger A.S. Detection of anti-Vibrio vulnificus cytolysin antibodies in sera from mice and a human surviving V. vulnificus disease. Infect. Immun. 51:1986;964-965.
5. Kreger A., Lockwood D. Detection of extracellular toxin(s) produced by Vibrio vulnificus. Infect. Immun. 33:1981;583-590.
6. Kothary M.H., Kreger A.S. Purification and characterization of an elastolytic protease of Vibrio vulnificus. J. Gen. Microbiol. 133:1987;1783-1791.
7. Miyoshi N., Shimizu C., Miyoshi S., Shinoda S. Purification and characterization of Vibrio vulnificus protease. Microbiol. Immunol. 31:1987;13-25.
8. Testa J., Daniel L.W., Kreger A.S. Extracellular phospholipase A2 and lysophospholipase produced by Vibrio vulnificus. Infect. Immun. 45:1984;458-463.
9. Wright A.C., Simpson L.M., Oliver J.D., Morris J.G. Jr. Phenotypic evaluation of acapsular transposon mutants of Vibrio vulnificus. Infect. Immun. 58:1990;1769-1773.
10. Simpson L.M., Oliver J.D. Siderophore production by Vibrio vulnificus. Infect. Immun. 41:1983;644-649.
11. Jeong K.C., Jeong H.S., Rhee J.H., Lee S.E., Chung S.S., Starks A.M., Escudero G.M., Gulig P.A., Choi S.H. Construction and phenotypic evaluation of a Vibrio vulnificus vvpE mutant for elastolytic protease. Infect. Immun. 68:2000;5096-5106.
12. Wright A.C., Morris L.G. Jr. The extracellular cytolysin of Vibrio vulnificus: inactivation and relationship to virulence in mice. Infect. Immun. 59:1991;192-197.
13. Shao C.P., Hor L.I. Metalloprotease is not essential for Vibrio vulnificus virulence in mice. Infect. Immun. 68:2000;3569-3573.
14. Fan J.J., Shao C.P., Ho Y.C., Yu C.K., Hor L.I. Isolation and characterization of a Vibrio vulnificus mutant deficient in both extracellular metalloprotease and cytolysin. Infect. Immun. 69:2001;5943-5948.
15. Rubin E.J., Akerley B.J., Novik V.N., Lampe D.J., Husson R.N., Mekalanos J.J. In vivo transposition of mariner-based elements in enteric bacteria and mycobacteria. Proc. Natl. Acad. Sci. USA. 16:1999;1645-1650.
16. Akerley B.J., Rubin E.J., Camilli A., Lampe D.J., Robertson H.M., Mekalanos J.J. Systematic identification of essential genes by in vitro mariner mutagenesis. Proc. Natl. Acad. Sci. USA. 95:1998;8927-8932.
17. Miller V.L., Mekalanos J.J. A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determination on Vibrio cholerae requires toxR. J. Bacteriol. 170:1988;2575-2583.
18. Reyrat J.M., Pelicic V., Gicquel B., Rappuoli R. Counter selectable markers: untapped tools for bacterial genetics and pathogenesis. Infect. Immun. 66:1998;4011-4017.
19. Simon R., Priefer R., Puhler A. A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in Gram-negative bacteria. Bio/Technology. 1:1983;784-791.
20. Shinoda S., Miyoshi S., Yamanaka H., Miyoshi-Nakahara N. Some properties of Vibrio vulnificus hemolysin. Microbiol. Immunol. 29:1985;583-590.
21. Surette M.G., Miller M.B., Bassler B.L. Quorum sensing in Escherichia coli, Salmonella typhimurium, and Vibrio harveyi: a new family of genes responsible for autoinducer production. Proc. Natl. Acad. Sci. USA. 96:1999;1639-1644.
22. Reed L.J., Muench H. A simple method of estimating the 50% end points. Am. J. Hyg. 27:1983;493-497.
23. McCarter L.L. Polar flagellar motility of the Vibrionaceae. Microbiol. Mol. Biol. Rev. 65:2001;445-462.
24. Ballado T., Camarena L., Gonzalez-Pedrajo B., Silva-Herzog E., Dreyfus G. The hook gene (flgE) is expressed from the flgBCDEF operon in Rhodobacter sphaeroides: study of an flgE mutant. J. Bacteriol. 183:2001;1680-1687.
25. Litwin C.M., Rayback T.W., Skinner J. Role of catechol siderophore synthesis in Vibrio vulnificus virulence. Infect. Immun. 64:1996;2834-2838.
26. Girón J.A., Torres A.G., Freer E., Kaper J.B. The flagella of enteropathogenic Escherichia coli mediate adherence to epithelial cells. Mol. Microbiol. 44:2002;361-379.
27. Kubori T., Matsushima Y., Nakamura D., Uralil J., Lara-Tejero M., Sukhan A., Galan J.E., Aizawa S.I. Supramolecular structure of the Salmonella typhimurium type III secretion system. Science. 280:1998;602-605.
28. Young B.M., Young G.M. YplA is exported by the Ysc, Ysa, and flagellar type III secretion systems of Yersinia enterocolitica. J. Bacteriol. 184:2002;1324-1334.