Construction and phenotypic evaluation of a Vibrio vulnificus vvpE mutant for elastolytic protease

Infection and Immunity

Volumn 68, Issue 9, 2000, Pages 5096-5106

  Kwang Cheol Jeong, ^a   Hye Sook Jeong, ^a   Joon Haeng Rhee, ^a   Shee Eun Lee, ^a   Sun Sik Chung, ^a   Starks, A M ^a   Escudero, G M ^a   Gulig, P A ^a   Sang Ho Choi, ^a  

^a Chonnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ELASTASE; PROTEINASE; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL VIRULENCE; BACTERIUM MUTANT; CONTROLLED STUDY; CYTOLYSIS; EPITHELIUM CELL; FATALITY; FOOD CONTAMINATION; GENE INACTIVATION; HISTOPATHOLOGY; KNOCKOUT MOUSE; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OYSTER; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPSIS; SEQUENCE ANALYSIS; SOUTHERN BLOTTING; VIBRIO VULNIFICUS; WOUND INFECTION;

ANIMALS; BACTERIAL PROTEINS; CLONING, MOLECULAR; FEMALE; METALLOENDOPEPTIDASES; MICE; MICE, INBRED ICR; PANCREATIC ELASTASE; PHENOTYPE; RNA, MESSENGER; VIBRIO; VIRULENCE;

EID: 0033855435     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.68.9.5096-5106.2000     Document Type: Article

References (58)

1. Basic local alignment search tool
2. Diseases of humans (other than cholera) caused by vibrios
3. Edema and hemoconcentration in mice experimentally infected with Vibrio vulnificus
4. Cloning and nucleotide sequencing of the protease gene of Vibrio vulnificus
5. Cloning and characterization of the gene (empV) encoding extracellular metalloprotease from Vibrio vulnificus
6. Molecular Koch's postulates applied to microbial pathogenicity
7. Pseudomonas aeruginosa elastase and elastolysis revisited: Recent developments
8. Cloning and characterization of the Pseudomonas aeruginosa lasR gene, a transcriptional activator of elastase expression
9. Identification of protein coding regions by database similarity search
10. Mouse skin damage caused by cytolysin from Vibrio vulnificus and by V. vulnificus infection
11. Use of isogenic mutants to study bacterial virulence factors
12. Bacterial extracellular zinc-containing metalloproteases
13. Improved broad-host-range plasmids for DNA cloning in gram-negative bacteria
14. Syndromes of Vibrio vulnificus infections. Clinical and epidemiologic features in Florida cases, 1981-1987
15. Trans-complementation-dependent replication of a low molecular weight origin fragment from plasmid R6K
16. Production and partial characterization of an elastolytic protease of Vibrio vulnificus
17. Purification and characterization of an elastolytic protease of Vibrio vulnificus
18. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
19. Role of catechol siderophore synthesis in Vibrio vulnificus virulence
20. Involvement of bradykinin generation in intravascular dissemination of Vibrio vulnificus and prevention of invasion by a bradykinin antagonist
21. A novel suicide vector and its use in construction of insertion mutations: Osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR
22. Cloning of a metalloprotease gene involved in the virulence mechanism of Vibrio anguillarum
23. Activation of the plasma kallikrein-kinin system by Vibrio vulnificus protease
24. Purification and characterization of Vibrio vulnificus protease
25. Vibrio vulnificus may produce a metalloprotease causing an edematous skin lesion in vivo
26. Characterization of the hemorrhagic reaction caused by Vibrio vulnificus metalloprotease, a member of the thermolysin family
27. Role of the protease in the permeability enhancement by Vibrio vulnificus
28. 2-macroglobulin on Vibrio vulnificus protease
29. Alpha-macroglobulin-like plasma inactivator for Vibrio vulnificus metalloprotease
30. Activation mechanism of human Hageman factor-plasma kallikrein-kinin system by Vibrio vulnificus metalloprotease
31. Functional domains of a zinc metalloprotease from Vibrio vulnificus
32. Activation of hageman factor and prekallikrein and generation of kinin by various microbial proteinases
33. Escherichia coli fliAZY operon
34. Significant role of an exocellular protease in utilization of heme by Vibrio vulnificus
35. Involvement of vulnibactin and exocellular protease in utilization of transferrin- and lactoferrin-bound iron by Vibrio vulnificus
36. Production of extracellular enzymes and cytotoxicity by Vibrio vulnificus
37. The type IV leader peptidase/N-methyltransferase of Vibrio vulnificus controls factors required for adherence to HEp-2 cells and virulence in iron-overloaded mice
38. Pulmonary damage by Vibrio vulnificus cytolysin
39. Pseudomonas metalloproteases and host-microbe relationship
40. A simple method of estimating fifty percent endpoints
41. Purification and physico-chemical characterization of rabbit tumor necrosis factor
42. Some properties of Vibrio vulnificus hemolysin
43. Phenotypic characterization
44. A broad-host-range mobilization system for in vivo genetic engineering: Transposon mutagenesis in gram-negative bacteria
45. Correlation between virulence and colony morphology in Vibrio vulnificus
46. Pathogenesis of infection by clinical and environmental strains of Vibrio vulnificus in iron dextran-treated mice
47. Clinical features and an epidemiological study of Vibrio vulnificus infections
48. Extracellular phospholipase A2 and lysophospholipase produced by Vibrio vulnificus
49. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
50. Multiple fimbrial adhesins are required for full virulence of Salmonella typhimurium in mice
51. A new method for predicting signal sequence cleavage sites
52. The extracellular cytolysin of Vibrio vulnificus: Inactivation and relationship to virulence in mice
53. Cloning of the cytotoxin-hemolysin gene of Vibrio vulnificus
54. Role of iron in the pathogenesis of Vibrio vulnificus infections
55. Phenotypic evaluation of acapsular transposon mutants of Vibrio vulnificus
56. Cytolytic action of Vibrio vulnificus haemolysin on mast cells from rat peritoneal cavity
57. Relation of capsular materials and colony opacity to virulence of Vibrio vulnificus