Stereoselective synthesis of β-lactams with polyaromatic imines: Entry to new and novel anticancer agents

Journal of Medicinal Chemistry

Volumn 46, Issue 1, 2003, Pages 12-15

  Banik, Indrani ^a   Becker, Frederick F ^a   Banik, Bimal K ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; AZETIDINONE DERIVATIVE; BETA LACTAM DERIVATIVE; IMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; DRUG POTENCY; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; STAUDINGER REACTION; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTINEOPLASTIC AGENTS; BETA-LACTAMS; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; IMINES; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0037413527     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0255825     Document Type: Article

References (43)

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25. Also see: (a) Becker, F. F.; Banik, B. K. US Patent 6015811, 2000.
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29. We have devised methods for the synthesis of polyaromatic nitro compounds and amines described in this paper. For example, see: (a) Banik, B. K.; Mukhopadhyay, C.; Venkatraman, M. S.; Becker, F. F. A facile reduction of aromatic nitro compounds to aromatic amines by samarium and iodine. Tetrahedron Lett. 1998, 39, 7243-7247. (b) Banik, B. K.; Suhendra, M.; Banik, I.; Becker, F. F. Indium/ammonium chloride mediated reduction of aromatic nitro compounds: Practical synthesis of 6-amino chrysene. Synth. Commun. 2000, 30, 3745-3754. (c) Basu, M. K.; Becker, F. F.; Banik, B. K. Ultrasound-promoted highly efficient reduction of aromatic nitro compounds to the aromatic amines by samarium/ammonium chloride. Tetrahedron Lett. 2001, 41, 6551-6554. (d) Samajdar, S.; Becker, F. F.; Banik, B. K. Surface-mediated highly efficient regioselective nitration of aromatic compounds by bismuth nitrate. Tetrahedron Lett. 2000, 41, 8017-8020.
30. We have devised methods for the synthesis of polyaromatic nitro compounds and amines described in this paper. For example, see: (a) Banik, B. K.; Mukhopadhyay, C.; Venkatraman, M. S.; Becker, F. F. A facile reduction of aromatic nitro compounds to aromatic amines by samarium and iodine. Tetrahedron Lett. 1998, 39, 7243-7247. (b) Banik, B. K.; Suhendra, M.; Banik, I.; Becker, F. F. Indium/ammonium chloride mediated reduction of aromatic nitro compounds: Practical synthesis of 6-amino chrysene. Synth. Commun. 2000, 30, 3745-3754. (c) Basu, M. K.; Becker, F. F.; Banik, B. K. Ultrasound-promoted highly efficient reduction of aromatic nitro compounds to the aromatic amines by samarium/ammonium chloride. Tetrahedron Lett. 2001, 41, 6551-6554. (d) Samajdar, S.; Becker, F. F.; Banik, B. K. Surface-mediated highly efficient regioselective nitration of aromatic compounds by bismuth nitrate. Tetrahedron Lett. 2000, 41, 8017-8020.
31. We have devised methods for the synthesis of polyaromatic nitro compounds and amines described in this paper. For example, see: (a) Banik, B. K.; Mukhopadhyay, C.; Venkatraman, M. S.; Becker, F. F. A facile reduction of aromatic nitro compounds to aromatic amines by samarium and iodine. Tetrahedron Lett. 1998, 39, 7243-7247. (b) Banik, B. K.; Suhendra, M.; Banik, I.; Becker, F. F. Indium/ammonium chloride mediated reduction of aromatic nitro compounds: Practical synthesis of 6-amino chrysene. Synth. Commun. 2000, 30, 3745-3754. (c) Basu, M. K.; Becker, F. F.; Banik, B. K. Ultrasound-promoted highly efficient reduction of aromatic nitro compounds to the aromatic amines by samarium/ammonium chloride. Tetrahedron Lett. 2001, 41, 6551-6554. (d) Samajdar, S.; Becker, F. F.; Banik, B. K. Surface-mediated highly efficient regioselective nitration of aromatic compounds by bismuth nitrate. Tetrahedron Lett. 2000, 41, 8017-8020.
32. We have devised methods for the synthesis of polyaromatic nitro compounds and amines described in this paper. For example, see: (a) Banik, B. K.; Mukhopadhyay, C.; Venkatraman, M. S.; Becker, F. F. A facile reduction of aromatic nitro compounds to aromatic amines by samarium and iodine. Tetrahedron Lett. 1998, 39, 7243-7247. (b) Banik, B. K.; Suhendra, M.; Banik, I.; Becker, F. F. Indium/ammonium chloride mediated reduction of aromatic nitro compounds: Practical synthesis of 6-amino chrysene. Synth. Commun. 2000, 30, 3745-3754. (c) Basu, M. K.; Becker, F. F.; Banik, B. K. Ultrasound-promoted highly efficient reduction of aromatic nitro compounds to the aromatic amines by samarium/ammonium chloride. Tetrahedron Lett. 2001, 41, 6551-6554. (d) Samajdar, S.; Becker, F. F.; Banik, B. K. Surface-mediated highly efficient regioselective nitration of aromatic compounds by bismuth nitrate. Tetrahedron Lett. 2000, 41, 8017-8020.
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