Immunologically specific activation of a cephalosporin derivative mitomycin C by monoclonal antibody β-lactamase conjugates

Journal of Medicinal Chemistry

Volumn 40, Issue 17, 1997, Pages 2788-2792

  Vrudhula, V M ^a   Svensson, H P ^a   Senter, P D ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE; CEPHALOSPORIN DERIVATIVE; MITOMYCIN C; MONOCLONAL ANTIBODY;

ANTINEOPLASTIC ACTIVITY; ARTICLE; COMBINATION CHEMOTHERAPY; CYTOTOXICITY; DRUG SYNTHESIS; ENTEROBACTER CLOACAE; ENZYME ACTIVATION; HYDROLYSIS; NONHUMAN;

ANTIBODIES, MONOCLONAL; BETA-LACTAMASES; CEPHALOSPORINS; HUMANS; MACROMOLECULAR SUBSTANCES; MITOMYCIN; MITOMYCINS; MODELS, CHEMICAL; PRODRUGS; TUMOR CELLS, CULTURED;

EID: 0030814274     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970108y     Document Type: Article

References (16)