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Volumn 37, Issue 12, 2003, Pages 1177-1186

Evidence for multiple sterol methyl transferase pathways in Pneumocystis carinii

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOSYNTHESIS; CHOLESTEROL; CHROMATOGRAPHIC ANALYSIS; ENZYMES; FUNGI; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

EID: 0037413196     PISSN: 00244201     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11745-002-1018-8     Document Type: Conference Paper
Times cited : (17)

References (40)
  • 2
    • 0028056625 scopus 로고
    • Evidence for the presence of "metabolic sterols" in Pneumocystis: Identification and Initial characterization of Pneumocystis carinii sterols
    • Kaneshiro, E.S., Ellis, J.E., Jayasimhulu, K., and Beach, D.H. (1994) Evidence for the Presence of "Metabolic Sterols" in Pneumocystis: Identification and Initial Characterization of Pneumocystis carinii Sterols, J. Eukaryot. Microbiol. 4, 78-85.
    • (1994) J. Eukaryot. Microbiol. , vol.4 , pp. 78-85
    • Kaneshiro, E.S.1    Ellis, J.E.2    Jayasimhulu, K.3    Beach, D.H.4
  • 3
    • 13044269649 scopus 로고    scopus 로고
    • Pneumocysterol [(24Z)-ethylidenelanost-8-en-3β-ol], a rare sterol detected in the opportunistic pathogen Pneumocystis carinii hominis: Structural identity and chemical synthesis
    • Kaneshiro, E.S., Amit, Z., Swonger, M.M., Kreishman, G.P., Brooks, E.E., Kreishman, M., Jayasimhulu, K., Parish, E.J., Sun, H., Kizito, S.A., et al. (1999) Pneumocysterol [(24Z)-ethylidenelanost-8-en-3β-ol], a Rare Sterol Detected in the Opportunistic Pathogen Pneumocystis carinii hominis: Structural Identity and Chemical Synthesis, Proc. Natl. Acad. Sci. USA 96, 97-102.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 97-102
    • Kaneshiro, E.S.1    Amit, Z.2    Swonger, M.M.3    Kreishman, G.P.4    Brooks, E.E.5    Kreishman, M.6    Jayasimhulu, K.7    Parish, E.J.8    Sun, H.9    Kizito, S.A.10
  • 6
    • 0029026405 scopus 로고
    • Multiple origins of lichen symbioses in fungi suggested by SSU rDNA phylogeny
    • Gargas, A., DePriest, P.T., Grube, M., and Tehler, A. (1995) Multiple Origins of Lichen Symbioses in Fungi Suggested by SSU rDNA Phylogeny, Science 268, 1492-1495.
    • (1995) Science , vol.268 , pp. 1492-1495
    • Gargas, A.1    DePriest, P.T.2    Grube, M.3    Tehler, A.4
  • 7
    • 0031797193 scopus 로고    scopus 로고
    • Taxonomy, genetic organization, and life cycle of Pneumocystis carinii
    • Cushion, M.T. (1998) Taxonomy, Genetic Organization, and Life Cycle of Pneumocystis carinii, Semin. Respir. Infect. 13, 304-312.
    • (1998) Semin. Respir. Infect. , vol.13 , pp. 304-312
    • Cushion, M.T.1
  • 9
    • 0032080517 scopus 로고    scopus 로고
    • Plant sterols and the membrane environment
    • Hartman, M. (1998) Plant Sterols and the Membrane Environment, Trends Plant Sci. 3, 170-174.
    • (1998) Trends Plant Sci. , vol.3 , pp. 170-174
    • Hartman, M.1
  • 10
    • 0001273785 scopus 로고
    • Biosynthesis and requirement for sterols in the growth and reproduction of oomycetes
    • Nes, W.D. (1987) Biosynthesis and Requirement for Sterols in the Growth and Reproduction of Oomycetes, Am. Chem. Soc. Symp. Ser. 325, 304-328.
    • (1987) Am. Chem. Soc. Symp. Ser. , vol.325 , pp. 304-328
    • Nes, W.D.1
  • 11
    • 0027205567 scopus 로고
    • The structural requirements of sterol for membrane function in Saccharomyces cerevisiae
    • Nes, W.D., Janssen, G.G., Crumley, F.G., Kalinowska, M., and Akihisa, T. (1993) The Structural Requirements of Sterol for Membrane Function in Saccharomyces cerevisiae, Arch. Biochem. Biophys. 300, 724-733.
    • (1993) Arch. Biochem. Biophys. , vol.300 , pp. 724-733
    • Nes, W.D.1    Janssen, G.G.2    Crumley, F.G.3    Kalinowska, M.4    Akihisa, T.5
  • 12
    • 0013369492 scopus 로고
    • Biosynthetic intermediates in the conversion of fucosterol and oogoniol
    • White, R.H., and McMorris, T.C. (1978) Biosynthetic Intermediates in the Conversion of Fucosterol and Oogoniol, Phytochemistry 17, 1800-1802.
    • (1978) Phytochemistry , vol.17 , pp. 1800-1802
    • White, R.H.1    McMorris, T.C.2
  • 13
    • 38249021968 scopus 로고
    • Fatty and sterols of selected hypochytriomycetes and chytridromycetes
    • Weete, J.D., Fuller, M.S., Huang, H.Q., and Gandhi, S. (1989) Fatty and Sterols of Selected Hypochytriomycetes and Chytridromycetes, Exp. Mycol. 13, 183-195.
    • (1989) Exp. Mycol. , vol.13 , pp. 183-195
    • Weete, J.D.1    Fuller, M.S.2    Huang, H.Q.3    Gandhi, S.4
  • 14
    • 0031461227 scopus 로고    scopus 로고
    • Sterols of the Phylum Zygomycota: Phylogenetic implications
    • Weete, J.D., and Gandhi, S.R. (1997) Sterols of the Phylum Zygomycota: Phylogenetic Implications, Lipids 32, 1309-1316.
    • (1997) Lipids , vol.32 , pp. 1309-1316
    • Weete, J.D.1    Gandhi, S.R.2
  • 15
    • 0001890045 scopus 로고
    • Phylogenetic distribution of sterols
    • Patterson, G.W. (1994) Phylogenetic Distribution of Sterols, Am. Chem. Soc. Symp. Ser. 562, 90-108.
    • (1994) Am. Chem. Soc. Symp. Ser. , vol.562 , pp. 90-108
    • Patterson, G.W.1
  • 16
    • 0020608864 scopus 로고
    • Influence of l'anaerobiose sur la composition en sterols de Mucor hiemalis
    • Herber, R., Villoutreix, J., Granger, P., and Chapelle, S. (1983) Influence of l'Anaerobiose sur la Composition en Sterols de Mucor hiemalis, Can. J. Microbiol. 29, 606-611.
    • (1983) Can. J. Microbiol. , vol.29 , pp. 606-611
    • Herber, R.1    Villoutreix, J.2    Granger, P.3    Chapelle, S.4
  • 17
    • 0013323861 scopus 로고
    • Revision of C-22, C-23 configurations of two triterpenoids of the fungus Pisolithus tinctorius
    • Abreu, P.M., Lobo, M., and Prabhakar, S. (1991) Revision of C-22, C-23 Configurations of Two Triterpenoids of the Fungus Pisolithus tinctorius, Phytochemistry 30, 3818-3819.
    • (1991) Phytochemistry , vol.30 , pp. 3818-3819
    • Abreu, P.M.1    Lobo, M.2    Prabhakar, S.3
  • 20
    • 0027944204 scopus 로고
    • Use of an ATP bioluminescent assay to evaluate viability of Pneumocystis carinii from rats
    • Chen, F., and Cushion, M.T. (1994) Use of an ATP Bioluminescent Assay to Evaluate Viability of Pneumocystis carinii from Rats, J. Clin. Microbiol. 32, 2791-2800.
    • (1994) J. Clin. Microbiol. , vol.32 , pp. 2791-2800
    • Chen, F.1    Cushion, M.T.2
  • 21
    • 0031039940 scopus 로고    scopus 로고
    • A cytotoxicity assay for evaluation of candidate anti-pneumocystis agents
    • Cushion, M.T., Chen, F., and Kloepfer, N. (1997) A Cytotoxicity Assay for Evaluation of Candidate Anti-Pneumocystis Agents, Antimicrob. Agents. Chemother. 41, 379-384.
    • (1997) Antimicrob. Agents. Chemother. , vol.41 , pp. 379-384
    • Cushion, M.T.1    Chen, F.2    Kloepfer, N.3
  • 22
    • 0026033821 scopus 로고
    • Identification of ergosta-6(7),8(14),25(27)-trien-3β-ol and ergosta-5(6),7(8),25(27)-trien-3β-ol. Two New Steroidal Trienes Synthesized by Prototheca wickerhamii
    • Norton, R.A., and Nes, W.D. (1991) Identification of Ergosta-6(7),8(14),25(27)-trien-3β-ol and Ergosta-5(6),7(8),25(27)-trien-3β-ol, Two New Steroidal Trienes Synthesized by Prototheca wickerhamii, Lipids 26, 247-249.
    • (1991) Lipids , vol.26 , pp. 247-249
    • Norton, R.A.1    Nes, W.D.2
  • 23
    • 0028948226 scopus 로고
    • Developmental regulation of sterol biosynthesis in zea mays
    • Guo, D., Venkatramesh, M., and Nes, W.D. (1995) Developmental Regulation of Sterol Biosynthesis in Zea mays, Lipids 30, 203-219.
    • (1995) Lipids , vol.30 , pp. 203-219
    • Guo, D.1    Venkatramesh, M.2    Nes, W.D.3
  • 25
    • 0025021898 scopus 로고
    • Evidence for separate intermediates in the biosynthesis of 24β-methyl sterols end products by Gibberella fujikuori
    • Nes, W.D., and Le, P.H. (1990) Evidence for Separate Intermediates in the Biosynthesis of 24β-Methyl Sterols End Products by Gibberella fujikuori, Biochim. Biophys. Acta 1042, 119-125.
    • (1990) Biochim. Biophys. Acta , vol.1042 , pp. 119-125
    • Nes, W.D.1    Le, P.H.2
  • 26
    • 0024333788 scopus 로고
    • Evidence for similarities and differences in the biosynthesis of fungal sterols
    • Nes, W.D., Xu, S., and Haddon, W.F. (1988) Evidence for Similarities and Differences in the Biosynthesis of Fungal Sterols, Steroids 53, 533-558.
    • (1988) Steroids , vol.53 , pp. 533-558
    • Nes, W.D.1    Xu, S.2    Haddon, W.F.3
  • 27
    • 0037163251 scopus 로고    scopus 로고
    • 25(27)-olefins by a single plant enzyme
    • 25(27)-Olefins by a Single Plant Enzyme, Tetrahedron Lett. 43, 7017-7021.
    • (2002) Tetrahedron Lett. , vol.43 , pp. 7017-7021
    • Dennis, A.L.1    Nes, W.D.2
  • 28
    • 0017290706 scopus 로고
    • Configuration at C-24 of 24-methyl and 24-ethylcholesterol
    • Nes, W.R., Krevitz, K., and Behzadan, S. (1976) Configuration at C-24 of 24-Methyl and 24-Ethylcholesterol, Lipids 11, 118-126.
    • (1976) Lipids , vol.11 , pp. 118-126
    • Nes, W.R.1    Krevitz, K.2    Behzadan, S.3
  • 29
    • 0022565553 scopus 로고
    • Evidence for facilitated transport in the absorption of sterols by Saccharomyces cerevisiae
    • Nes, W.R., Dhanuka, I.C., and Pinto, W.J. (1986) Evidence for Facilitated Transport in the Absorption of Sterols by Saccharomyces cerevisiae, Lipids 21, 102-106.
    • (1986) Lipids , vol.21 , pp. 102-106
    • Nes, W.R.1    Dhanuka, I.C.2    Pinto, W.J.3
  • 30
    • 0020522411 scopus 로고
    • Stereochemical specificity for sterols in Saccharomyces cerevisiae
    • Pinto, W.J., and Nes, W.R. (1983) Stereochemical Specificity for Sterols in Saccharomyces cerevisiae, J. Biol. Chem. 258, 4472-4476.
    • (1983) J. Biol. Chem. , vol.258 , pp. 4472-4476
    • Pinto, W.J.1    Nes, W.R.2
  • 33
    • 0034672702 scopus 로고    scopus 로고
    • Sterol methyl transferase: Enzymology and inhibition
    • Nes, W.D. (2000) Sterol Methyl Transferase: Enzymology and Inhibition, Biochim. Biophys. Acta 1529, 63-88.
    • (2000) Biochim. Biophys. Acta , vol.1529 , pp. 63-88
    • Nes, W.D.1
  • 35
    • 0033525499 scopus 로고    scopus 로고
    • Site-directed mutagenesis of the sterol methyl transferase active site from Saccharomyces cerevisiae results in formation of novel 24-ethyl sterols
    • Nes, W.D., McCourt, B.S., Marshall, J.A., Ma, J., Dennis, A.L., Lopez, M., and Le, H. (1999) Site-Directed Mutagenesis of the Sterol Methyl Transferase Active Site from Saccharomyces cerevisiae Results in Formation of Novel 24-Ethyl Sterols, J. Org. Chem. 64, 1535-1542.
    • (1999) J. Org. Chem. , vol.64 , pp. 1535-1542
    • Nes, W.D.1    McCourt, B.S.2    Marshall, J.A.3    Ma, J.4    Dennis, A.L.5    Lopez, M.6    Le, H.7
  • 36
    • 0037044738 scopus 로고    scopus 로고
    • Active site mapping and substrate channeling in the sterol methyl transferase pathway
    • Nes, W.D., Marshall, J.A., Jia, Z., Jaradat, T.T., Song, Z., and Jayasimha, P. (2002) Active Site Mapping and Substrate Channeling in the Sterol Methyl Transferase Pathway, J. Biol. Chem. 277, 42549-42556.
    • (2002) J. Biol. Chem. , vol.277 , pp. 42549-42556
    • Nes, W.D.1    Marshall, J.A.2    Jia, Z.3    Jaradat, T.T.4    Song, Z.5    Jayasimha, P.6
  • 37
    • 0028179364 scopus 로고
    • Widespread occurrence of three sequence motifs in diverse S-adenosylmethionine-dependent methyl transferases suggests a common structure for these enzymes
    • Kagan, R.M., and Clarke, S. (1994) Widespread Occurrence of Three Sequence Motifs in Diverse S-Adenosylmethionine-Dependent Methyl Transferases Suggests a Common Structure for These Enzymes, Arch. Biochem. Biophys. 310, 41-427.
    • (1994) Arch. Biochem. Biophys. , vol.310 , pp. 41-427
    • Kagan, R.M.1    Clarke, S.2
  • 38
    • 0033534476 scopus 로고    scopus 로고
    • S-adenosylmethionine-dependent methylation in Saccharomyces cerevisiae
    • Niewmierzycka, A., and Clarke, S. (1999) S-Adenosylmethionine-Dependent Methylation in Saccharomyces cerevisiae, J. Biol. Chem. 274, 814-824.
    • (1999) J. Biol. Chem. , vol.274 , pp. 814-824
    • Niewmierzycka, A.1    Clarke, S.2
  • 39
    • 0035144221 scopus 로고    scopus 로고
    • Plant enzyme structure. Explaining substrate specificity and the evolution of function
    • Hrmova, M., and Fincher, G.B. (2001) Plant Enzyme Structure. Explaining Substrate Specificity and the Evolution of Function, Plant Physiol. 125, 54-57.
    • (2001) Plant Physiol. , vol.125 , pp. 54-57
    • Hrmova, M.1    Fincher, G.B.2
  • 40
    • 0032528942 scopus 로고    scopus 로고
    • Two families of sterol methyl transferase are involved in the first and the second methylation steps of plant sterol biosynthesis
    • Bouvier-Nave, P., Husselstein, T., and Benveniste, P. (1998) Two Families of Sterol Methyl Transferase Are Involved in the First and the Second Methylation Steps of Plant Sterol Biosynthesis, Eur. J. Biochem. 256, 88-96.
    • (1998) Eur. J. Biochem. , vol.256 , pp. 88-96
    • Bouvier-Nave, P.1    Husselstein, T.2    Benveniste, P.3


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