Both Fcγ receptor I and fcγ receptor III mediate disease in accelerated nephrotoxic nephritis

American Journal of Pathology

Volumn 162, Issue 5, 2003, Pages 1677-1683

  Tarzi, Ruth M ^a   Davies, Kevin A ^a   Claassens, Jill W C ^a   Verbeek, J Sjef ^a   Walport, Mark J ^a   Cook, H Terence ^b  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

FC RECEPTOR; IMMUNOGLOBULIN G; RECEPTOR SUBUNIT; ISOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DISSOCIATION; FEMALE; GLOMERULONEPHRITIS; GLOMERULUS; GLOMERULUS BASEMENT MEMBRANE; IMMUNE COMPLEX NEPHRITIS; IMMUNE RESPONSE; KIDNEY INJURY; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR UPREGULATION; SHEEP; THROMBOSIS; ANIMAL; DISEASE COURSE; DISEASE MODEL; GENETICS; IMMUNOLOGY; MOUSE MUTANT; NEPHRITIS; PATHOLOGY; PHYSIOLOGY; SEXUAL DEVELOPMENT;

ANIMALS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FEMALE; IMMUNOGLOBULIN G; MALE; MICE; MICE, KNOCKOUT; NEPHRITIS; PROTEIN ISOFORMS; RECEPTORS, IGG; SEX CHARACTERISTICS; SHEEP;

EID: 0037407787     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)64302-7     Document Type: Article

References (25)

1. Ravetch JV, Bolland S: IgG Fc receptors. Annu Rev Immunol 2001, 19:275-290
2. Clynes R, Dumitru C, Ravetch JV: Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis. Science 1998, 279:1052-1054
3. Park SY, Ueda S, Ohno H, Hamano Y, Tanaka M, Shiratori T, Yamazaki T, Arase H, Arase N, Karasawa A, Sato S, Ledermann B, Kondo Y, Okumura K, Ra C, Saito T: Resistance of Fc receptordeficient mice to fatal glomerulonephritis. J Clin Invest 1998, 102:1229-1238
4. Suzuki Y, Shirato I, Okumura K, Ravetch JV, Takai T, Tomino Y, Ra C: Distinct contribution of Fc receptors and angiotensin II-dependent pathways in anti-GBM glomerulonephritis. Kidney Int 1998, 54:1166-1174
5. Wakayama H, Hasegawa Y, Kawabe T, Hara T, Matsuo S, Mizuno M, Takai T, Kikutani H, Shimokata K: Abolition of anti-glomerular basement membrane antibody-mediated glomerulonephritis in FcR-gamma-deficient mice. Eur J Immunol 2000, 30:1182-1190
6. Takai T, Li M, Sylvestre D, Clynes R, Ravetch JV: FcR gamma chain deletion results in pleiotrophic effector cell defects. Cell 1994, 76:519-529
7. Hazenbos WL, Gessner JE, Hofhuis FM, Kuipers H, Meyer D, Heijnen IA, Schmidt RE, Sandor M, Capel PJ, Daeron M, van de Winkel JG, Verbeek JS: Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice. Immunity 1996, 5:181-188
8. Hazenbos WL, Heijnen IA, Meyer D, Hofhuis FM, Renardel de Lavalette CR, Schmidt RE, Capel PJ, van de Winkel JG, Gessner JE, van den Berg TK, Verbeek JS: Murine IgG1 complexes trigger immune effector functions predominantly via Fc gamma RIII (CD16). J Immunol 1998, 161:3026-3032
9. Gavin AL, Leiter EH, Hogarth PM: Mouse FcgammaRI: identification and functional characterization of five new alleles. Immunogenetics 2000, 51:206-211
10. Takai T, Ono M, Hikida M, Ohmori H, Ravetch JV: Augmented humoral and anaphylactic responses in Fc gamma RII-deficient mice. Nature 1996, 379:346-349
11. Clynes R, Maizes JS, Guinamard R, Ono M, Takai T, Ravetch JV: Modulation of immune complex-induced inflammation in vivo by the coordinate expression of activation and inhibitory Fc receptors. J Exp Med 1999, 189:179-185
12. Nieswandt B, Bergmeier W, Schulte V, Rackebrandt K, Gessner JE, Zirngibl H: Expression and function of the mouse collagen receptor glycoprotein VI is strictly dependent on its association with the FcRgamma chain. J Biol Chem 2000, 275:23998-24002
13. Kubagawa H, Chen CC, Ho LH, Shimada TS, Gartland L, Mashburn C, Uehara T, Ravetch JV, Cooper MD: Biochemical nature and cellular distribution of the paired immunoglobulin-like receptors, PIR-A and PIR-B. J Exp Med 1999, 189:309-318
14. Arase N, Arase H, Park SY, Ohno H, Ra C, Saito T: Association with FcRgamma is essential for activation signal through NKR-P1 (CD161) in natural killer (NK) cells and NK1.1+ T cells. J Exp Med 1997, 186:1957-1963
15. loan-Facsinay A, de Kimpe SJ, Hellwig SM, van Lent PL, Hofhuis FM, van Ojik HH, Sedlik C, da Silveira SA, Gerber J, de Jong YF, Roozendaal R, Aarden LA, van den Berg WB, Saito T, Mosser D, Amigorena S, Izui S, van Ommen GJ, van Vugt M, van de Winkel JG, Verbeek JS: FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. Immunity 2002, 16:391-402
16. Barnes N, Gavin AL, Tan PS, Mottram P, Koentgen F, Hogarth PM: FcgammaRI-deficient mice show multiple alterations to inflammatory and immune responses. Immunity 2002, 16:379-389
17. Coxon A, Cullere X, Knight S, Sethi S, Wakelin MW, Stavrakis G, Luscinskas FW, Mayadas TN: Fc gamma RIII mediates neutrophil recruitment to immune complexes a mechanism for neutrophil accumulation in immune-mediated inflammation. Immunity 2001, 14:693-704
18. Huang XR, Tipping PG, Apostolopoulos J, Oettinger C, D'Souza M, Milton G, Holdsworth SR: Mechanisms of T cell-induced glomerular injury in anti-glomerular basement membrane (GBM) glonnerulonephritis in rats. Clin Exp Immunol 1997, 109:134-142
19. Tarzi RM, Davies KA, Robson MG, Fossati-Jimack L, Saito T, Walport MJ, Cook HT: Nephrotoxic nephritis is mediated by Fcgamma receptors on circulating leukocytes and not intrinsic renal cells. Kidney Int 2002, 62:2087-2096
20. Unkeless JC, Eisen HN: Binding of monomeric immunoglobulins to Fc receptors of mouse macrophages. J Exp Med 1975, 142:1520-1533
21. Kitching AR, Holdsworth SR, Tipping PG: IFN-gamma mediates crescent formation and cell-mediated immune injury in murine glomerulonephritis. J Am Soc Nephrol 1999, 10:752-759
22. Sivo J, Politis AD, Vogel SN: Differential effects of interferon-gamma and glucocorticoids on Fc gamma R gene expression in murine macrophages. J Leukoc Biol 1993, 54:451-457
23. Sylvestre DL, Ravetch JV: A dominant role for mast cell Fc receptors in the Arthus reaction. Immunity 1996, 5:387-390
24. Ji H, Ohmura K, Mahmood U, Lee DM, Hofhuis FM, Boackle SA, Takahashi K, Holers VM, Walport M, Gerard C, Ezekowitz A, Carroll MC, Brenner M, Weissleder R, Verbeek JS, Duchatelle V, Degott C, Benoist C, Mathis D: Arthritis critically dependent on innate immune system players. Immunity 2002, 16:157-168
25. van Lent PL, Nabbe K, Blom AB, Holthuysen AE, Sloeties A, van de Putte LB, Verbeek S, van den Berg WB: Role of activatory Fc gamma RI and Fc gamma RIII and inhibitory Fc gamma RII in inflammation and cartilage destruction during experimental antigen-induced arthritis. Am J Pathol 2001, 159:2309-2320