Comprehensive analysis of chromosome 1p deletions in neuroblastoma

Medical and Pediatric Oncology

Volumn 36, Issue 1, 2001, Pages 32-36

  White, P S ^a   Thompson, P M ^a   Seifried, B A ^b   Sulman, E P ^c   Jensen, S J ^d   Guo, C ^a   Maris, J M ^b   Hogarty, M D ^c   Allen, C ^d   Biegel, J A ^a   Matise, T C ^b   Gregory, S G ^c   Reynolds, C P ^d   Brodeur, G M ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Chromosome mapping; Chromosomes; Human; Neuroblastoma; Neuroblastoma therapy; Pair 1; Tumor suppressor genes

Indexed keywords

CANCER RECURRENCE; CANCER SURVIVAL; CHILD; CHROMOSOME 1; CHROMOSOME 1P; CHROMOSOME DELETION; CHROMOSOME MAP; CONFERENCE PAPER; CONTROLLED STUDY; CYTOGENETICS; GENETIC ANALYSIS; HETEROZYGOSITY LOSS; HUMAN; INFANT; MAJOR CLINICAL STUDY; NEUROBLASTOMA; ONCOGENE; ONCOGENE MYCN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; TUMOR SUPPRESSOR GENE;

ALLELES; CHILD; CHILD, PRESCHOOL; CHROMOSOME DELETION; CHROMOSOMES, HUMAN, PAIR 1; DISEASE-FREE SURVIVAL; GENES, TUMOR SUPPRESSOR; HUMANS; INFANT; LIFE TABLES; LOSS OF HETEROZYGOSITY; NEUROBLASTOMA; POLYMERASE CHAIN REACTION; PROPORTIONAL HAZARDS MODELS; RISK; SURVIVAL ANALYSIS;

EID: 0035169921     PISSN: 00981532     EISSN: None     Source Type: Journal    
DOI: 10.1002/1096-911X(20010101)36:1<32::AID-MPO1009>3.0.CO;2-0     Document Type: Conference Paper

References (20)

1. Chromosomal aberrations in human neuroblastomas
2. Molecular analysis of the region of distal 1p commonly deleted in neuroblastoma
3. A region of consistent deletion in neuroblastoma maps within human chromosome 1p36.2-36.3
4. Rapid detection of prognostic genetic factors in neuroblastoma using fluorescence in situ hybridisation on tumour imprints and bone marrow smears
5. Deletion of chromosome 1p loci and microsatellite instability in neuroblastomas analyzed with short-tandem repeat polymorphisms
6. Significance of chromosome 1p loss of heterozygosity in neuroblastoma
7. Allelic loss of chromosome 1p as a predictor of unfavorable outcome in patients with neuroblastoma
8. Biology and genetics of human neuroblastomas
9. Deletion mapping in neuroblastoma cell lines suggests two distinct tumor suppressor genes in the 1p35-36 region, only one of which is associated with N-myc amplification
10. Constitutional 1p36 deletion in a child with neuroblastoma
11. There may be two tumor suppressor genes on chromosome arm 1p closely associated with biologically distinct subtypes of neuroblastoma
12. Two distinct deleted regions on the short arm of chromosome 1 in neuroblastoma
13. Evidence for two tumour suppressor loci on chromosomal bands 1p35-36 involved in neuroblastoma: One probably imprinted, another associated with N-myc amplification
14. The 1p deletion is not a reliable marker for the prognosis of patients with neuroblastoma
15. Clinical relevance of loss of heterozygosity of the short arm of chromosome 1 in neuroblastoma: A single-institution study
16. Loss of chromosome 1p may have a prognostic value in localised neuroblastoma: Results of the French NBL 90 Study
17. A proposed staging for children with neuroblastoma
18. Histopathologic prognostic factors in neuroblastic tumors: Definition of subtypes of ganglioneuroblastoma and an age-linked classification of neuroblastomas
19. Neuroblastoma: Biology and therapy
20. A human modifier of methylation for class I HLA genes (MEMO-1) maps to chromosomal bands 1p35-36.1