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Volumn 284, Issue 5 53-5, 2003, Pages

The nonclassic secretion of thioredoxin is not sensitive to redox state

Author keywords

Protein secretion; Protein trafficking

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; BREFELDIN A; MUTANT PROTEIN; THIOREDOXIN;

EID: 0037405868     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00521.2002     Document Type: Article
Times cited : (34)

References (44)
  • 1
    • 0033775891 scopus 로고    scopus 로고
    • Physiological functions of thioredoxin and thioredoxin reductase
    • Arner ES and Holmgren A. Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem 267: 6102-6109, 2000.
    • (2000) Eur J Biochem , vol.267 , pp. 6102-6109
    • Arner, E.S.1    Holmgren, A.2
  • 2
    • 0030695172 scopus 로고    scopus 로고
    • Thioredoxin, a gene found overexpressed in human cancer, inhibits apoptosis in vitro and in vivo
    • Baker A, Payne CM, Briehl MM, and Powis G. Thioredoxin, a gene found overexpressed in human cancer, inhibits apoptosis in vitro and in vivo. Cancer Res 57: 5162-5167, 1997.
    • (1997) Cancer Res , vol.57 , pp. 5162-5167
    • Baker, A.1    Payne, C.M.2    Briehl, M.M.3    Powis, G.4
  • 3
    • 0025946128 scopus 로고
    • Human eosinophil cytotoxicity-enhancing factor. II. Multiple forms synthesized by U937 cells and their relationship to thioredoxin/adult T cell leukemia-derived factor
    • Balcewicz-Sablinska MK, Wollman EE, Gorti R, and Silberstein DS. Human eosinophil cytotoxicity-enhancing factor. II. Multiple forms synthesized by U937 cells and their relationship to thioredoxin/adult T cell leukemia-derived factor. J Immunol 147: 2170-2174, 1991.
    • (1991) J Immunol , vol.147 , pp. 2170-2174
    • Balcewicz-Sablinska, M.K.1    Wollman, E.E.2    Gorti, R.3    Silberstein, D.S.4
  • 4
    • 0030499036 scopus 로고    scopus 로고
    • Thioredoxin and thioredoxin reductase gene expression in human tumors and cell lines, and the effects of serum stimulation and hypoxia
    • Berggren M, Gallegos A, Gasdaska JR, Gasdaska PY, Warneke J, and Powis G. Thioredoxin and thioredoxin reductase gene expression in human tumors and cell lines, and the effects of serum stimulation and hypoxia. Anticancer Res 16: 3459-3466, 1996.
    • (1996) Anticancer Res , vol.16 , pp. 3459-3466
    • Berggren, M.1    Gallegos, A.2    Gasdaska, J.R.3    Gasdaska, P.Y.4    Warneke, J.5    Powis, G.6
  • 5
    • 0018987976 scopus 로고
    • Intracellular protein topogenesis
    • Blobel G. Intracellular protein topogenesis. Proc Natl Acad Sci USA 77: 1496-1500, 1980.
    • (1980) Proc Natl Acad Sci USA , vol.77 , pp. 1496-1500
    • Blobel, G.1
  • 7
    • 0030862924 scopus 로고    scopus 로고
    • HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region
    • Chang HC, Samaniego F, Nair BC, Buonaguro L, and Ensoli B. HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region. AIDS 11: 1421-1431, 1997.
    • (1997) AIDS , vol.11 , pp. 1421-1431
    • Chang, H.C.1    Samaniego, F.2    Nair, B.C.3    Buonaguro, L.4    Ensoli, B.5
  • 8
    • 0025760463 scopus 로고
    • Isolation from human placental extracts of a preparation possessing 'early pregnancy factor' activity and identification of the polypeptide components
    • Di Trapani G, Orosco C, Perkins A, and Clarke F. Isolation from human placental extracts of a preparation possessing 'early pregnancy factor' activity and identification of the polypeptide components. Hum Reprod 6: 450-457, 1991.
    • (1991) Hum Reprod , vol.6 , pp. 450-457
    • Di Trapani, G.1    Orosco, C.2    Perkins, A.3    Clarke, F.4
  • 9
    • 0031971129 scopus 로고    scopus 로고
    • Production and secretion of thioredoxin from transformed human trophoblast cells
    • Di Trapani G, Perkins A, and Clarke F. Production and secretion of thioredoxin from transformed human trophoblast cells. Mol Hum Reprod 4: 369-375, 1998.
    • (1998) Mol Hum Reprod , vol.4 , pp. 369-375
    • Di Trapani, G.1    Perkins, A.2    Clarke, F.3
  • 10
    • 0021670593 scopus 로고
    • Isolation of monoclonal antibodies specific for products of avian oncogene myb
    • Evan GI, Lewis GK, and Bishop JM. Isolation of monoclonal antibodies specific for products of avian oncogene myb. Mol Cell Biol 4: 2843-2850, 1984.
    • (1984) Mol Cell Biol , vol.4 , pp. 2843-2850
    • Evan, G.I.1    Lewis, G.K.2    Bishop, J.M.3
  • 12
    • 0028939001 scopus 로고
    • Quantitative export of FGF-2 occurs through an alternative, energy-dependent, non-ER/Golgi pathway
    • Florkiewicz RZ, Majack RA, Buechler RD, and Florkiewicz E. Quantitative export of FGF-2 occurs through an alternative, energy-dependent, non-ER/Golgi pathway. J Cell Physiol 162: 388-399, 1995.
    • (1995) J Cell Physiol , vol.162 , pp. 388-399
    • Florkiewicz, R.Z.1    Majack, R.A.2    Buechler, R.D.3    Florkiewicz, E.4
  • 13
    • 0025909444 scopus 로고
    • High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution
    • Forman-Kay JD, Clore GM, Wingfield PT, and Gronenborn AM. High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution. Biochemistry 30:2685-2698, 1991.
    • (1991) Biochemistry , vol.30 , pp. 2685-2698
    • Forman-Kay, J.D.1    Clore, G.M.2    Wingfield, P.T.3    Gronenborn, A.M.4
  • 14
    • 0029778527 scopus 로고    scopus 로고
    • Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells
    • Gallegos A, Gasdaska JR, Taylor CW, Painemurrieta GD, Goodman D, Gasdaska PY, Berggren M, Briehl MM, and Powis G. Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells. Cancer Res 56: 5765-5770, 1996.
    • (1996) Cancer Res , vol.56 , pp. 5765-5770
    • Gallegos, A.1    Gasdaska, J.R.2    Taylor, C.W.3    Painemurrieta, G.D.4    Goodman, D.5    Gasdaska, P.Y.6    Berggren, M.7    Briehl, M.M.8    Powis, G.9
  • 15
    • 0028818288 scopus 로고
    • Cell growth stimulation by the redox protein thioredoxin occurs by a novel helper mechanism
    • Gasdaska JR, Berggren M, and Powis G. Cell growth stimulation by the redox protein thioredoxin occurs by a novel helper mechanism. Cell Growth Differ 6: 1643-1650, 1995.
    • (1995) Cell Growth Differ , vol.6 , pp. 1643-1650
    • Gasdaska, J.R.1    Berggren, M.2    Powis, G.3
  • 16
    • 0030612880 scopus 로고    scopus 로고
    • Interleukin-1β secretion is impaired by inhibitors of the ATP binding cassette transporter, ABC1
    • Hamon Y, Luciani MF, Becq F, Verrier B, Rubartelli A, and Chimini G. Interleukin-1β secretion is impaired by inhibitors of the ATP binding cassette transporter, ABC1. Blood 90: 2911-2915, 1997.
    • (1997) Blood , vol.90 , pp. 2911-2915
    • Hamon, Y.1    Luciani, M.F.2    Becq, F.3    Verrier, B.4    Rubartelli, A.5    Chimini, G.6
  • 17
    • 0033600744 scopus 로고    scopus 로고
    • Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-κB
    • Hirota K, Murata M, Sachi Y, Nakamura H, Takeuchi J, Mori K, and Yodoi J. Distinct roles of thioredoxin in the cytoplasm and in the nucleus. A two-step mechanism of redox regulation of transcription factor NF-κB. J Biol Chem 274: 27891-27897, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 27891-27897
    • Hirota, K.1    Murata, M.2    Sachi, Y.3    Nakamura, H.4    Takeuchi, J.5    Mori, K.6    Yodoi, J.7
  • 18
    • 0031114040 scopus 로고    scopus 로고
    • Adult T cell leukemia (ATL)-derived factor/human thioredoxin prevents apoptosis of lymphoid cells induced by L-cystine and glutathione depletion: Possible involvement of thiol-mediated redox regulation in apoptosis caused by pro-oxidant state
    • Iwata S, Hori T, Sato N, Hirota K, Sasada T, Mitsui A, Hirakawa T, and Yodoi J. Adult T cell leukemia (ATL)-derived factor/human thioredoxin prevents apoptosis of lymphoid cells induced by L-cystine and glutathione depletion: possible involvement of thiol-mediated redox regulation in apoptosis caused by pro-oxidant state. J Immunol 158: 3108-3117, 1997.
    • (1997) J Immunol , vol.158 , pp. 3108-3117
    • Iwata, S.1    Hori, T.2    Sato, N.3    Hirota, K.4    Sasada, T.5    Mitsui, A.6    Hirakawa, T.7    Yodoi, J.8
  • 20
    • 0030994878 scopus 로고    scopus 로고
    • Plasma membrane targetting, vesicular budding and release of galectin 3 from the cytoplasm of mammalian cells during secretion
    • Mehul B and Hughes RC. Plasma membrane targetting, vesicular budding and release of galectin 3 from the cytoplasm of mammalian cells during secretion. J Cell Sci 110: 1169-1178, 1997.
    • (1997) J Cell Sci , vol.110 , pp. 1169-1178
    • Mehul, B.1    Hughes, R.C.2
  • 21
    • 0029042717 scopus 로고
    • Mechanisms of nuclear protein import
    • Melchior F and Gerace L. Mechanisms of nuclear protein import. Curr Opin Cell Biol 7: 310-318, 1995.
    • (1995) Curr Opin Cell Biol , vol.7 , pp. 310-318
    • Melchior, F.1    Gerace, L.2
  • 22
    • 0033199579 scopus 로고    scopus 로고
    • Determinants in the N-terminal domains of galectin-3 for secretion by a novel pathway circumventing the endoplasmic reticulum-Golgi complex
    • Menon RP and Hughes RC. Determinants in the N-terminal domains of galectin-3 for secretion by a novel pathway circumventing the endoplasmic reticulum-Golgi complex. Eur J Biochem 264:569-576, 1999.
    • (1999) Eur J Biochem , vol.264 , pp. 569-576
    • Menon, R.P.1    Hughes, R.C.2
  • 23
    • 0026975771 scopus 로고
    • Reactive oxygen-reducing and protein-refolding activities of adult T cell leukemia-derived factor/human thioredoxin
    • Mitsui A, Hirakawa T, and Yodoi J. Reactive oxygen-reducing and protein-refolding activities of adult T cell leukemia-derived factor/human thioredoxin. Biochem Biophys Res Commun 186: 1220-1226, 1992.
    • (1992) Biochem Biophys Res Commun , vol.186 , pp. 1220-1226
    • Mitsui, A.1    Hirakawa, T.2    Yodoi, J.3
  • 24
    • 0035956987 scopus 로고    scopus 로고
    • Chronic elevation of plasma thioredoxin: Inhibition of chemotaxis and curtailment of life expectancy in AIDS
    • Nakamura H, De Rosa SC, Yodoi J, Holmgren A, Ghezzi P, and Herzenberg LA. Chronic elevation of plasma thioredoxin: inhibition of chemotaxis and curtailment of life expectancy in AIDS. Proc Natl Acad Sci USA 98: 2688-2693, 2001.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 2688-2693
    • Nakamura, H.1    De Rosa, S.C.2    Yodoi, J.3    Holmgren, A.4    Ghezzi, P.5    Herzenberg, L.A.6
  • 26
    • 0034535383 scopus 로고    scopus 로고
    • Truncated thioredoxin is a mitogenic cytokine for resting human peripheral blood mononuclear cells and is present in human plasma
    • Pekkari K, Gurunath R, Arner ES, and Holmgren A. Truncated thioredoxin is a mitogenic cytokine for resting human peripheral blood mononuclear cells and is present in human plasma. J Biol Chem 275: 37474-37480, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 37474-37480
    • Pekkari, K.1    Gurunath, R.2    Arner, E.S.3    Holmgren, A.4
  • 27
    • 0035029131 scopus 로고    scopus 로고
    • Properties and biological activities of thioredoxins
    • Powis G and Montfort WR. Properties and biological activities of thioredoxins. Annu Rev Pharmacol Toxicol 41: 261-295, 2001.
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 261-295
    • Powis, G.1    Montfort, W.R.2
  • 28
    • 0026443077 scopus 로고
    • Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway
    • Rubartelli A, Bajetto A, Allavena G, Wollman E, and Sitia R. Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway. J Biol Chem 267: 24161-24164, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 24161-24164
    • Rubartelli, A.1    Bajetto, A.2    Allavena, G.3    Wollman, E.4    Sitia, R.5
  • 29
    • 0025255629 scopus 로고
    • A novel secretory pathway for interleukin-1β, a protein lacking a signal sequence
    • Rubartelli A, Cozzolino F, Talio M, and Sitia R. A novel secretory pathway for interleukin-1β, a protein lacking a signal sequence. EMBO J 9: 1503-1510, 1990.
    • (1990) EMBO J , vol.9 , pp. 1503-1510
    • Rubartelli, A.1    Cozzolino, F.2    Talio, M.3    Sitia, R.4
  • 30
    • 0025727177 scopus 로고
    • Interleukin 1β and thioredoxin are secreted through a novel pathway of secretion
    • Rubartelli A and Sitia R. Interleukin 1β and thioredoxin are secreted through a novel pathway of secretion. Biochem Soc Trans 19: 255-259, 1991.
    • (1991) Biochem Soc Trans , vol.19 , pp. 255-259
    • Rubartelli, A.1    Sitia, R.2
  • 31
    • 0031563783 scopus 로고    scopus 로고
    • Thioredoxin expression and localization in human cell lines: Detection of full-length and truncated species
    • Sahaf B, Soderberg A, Spyrou G, Barral AM, Pekkari K, Holmgren A, and Rosen A. Thioredoxin expression and localization in human cell lines: detection of full-length and truncated species. Exp Cell Res 236: 181-192, 1997.
    • (1997) Exp Cell Res , vol.236 , pp. 181-192
    • Sahaf, B.1    Soderberg, A.2    Spyrou, G.3    Barral, A.M.4    Pekkari, K.5    Holmgren, A.6    Rosen, A.7
  • 33
    • 0023024475 scopus 로고
    • Temperature-sensitive steps in the transport of secretory proteins through the Golgi complex in exocrine pancreatic cells
    • Saraste J, Palade GE, and Farquhar MG. Temperature-sensitive steps in the transport of secretory proteins through the Golgi complex in exocrine pancreatic cells. Proc Natl Acad Sci USA 83: 6425-6429, 1986.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 6425-6429
    • Saraste, J.1    Palade, G.E.2    Farquhar, M.G.3
  • 34
    • 0023186702 scopus 로고
    • Characterization of a factor from the U937 cell line that enhances the toxicity of human eosinophils to Schistosoma mansoni larvae
    • Silberstein DS, Dessein AJ, Elsas PP, Fontaine B, and David JR. Characterization of a factor from the U937 cell line that enhances the toxicity of human eosinophils to Schistosoma mansoni larvae. J Immunol 138: 3042-3050, 1987.
    • (1987) J Immunol , vol.138 , pp. 3042-3050
    • Silberstein, D.S.1    Dessein, A.J.2    Elsas, P.P.3    Fontaine, B.4    David, J.R.5
  • 35
    • 0027457715 scopus 로고
    • Human eosinophil cytotoxicity-enhancing factor eosinophil-stimulating and dithiol reductase activities of biosynthetic (recombinant) species with COOH-terminal deletions
    • Silberstein DS, McDonough S, Minkoff MS, and Balcewicz-Sablinska MK. Human eosinophil cytotoxicity-enhancing factor eosinophil-stimulating and dithiol reductase activities of biosynthetic (recombinant) species with COOH-terminal deletions. J Biol Chem 268: 9138-9142, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 9138-9142
    • Silberstein, D.S.1    McDonough, S.2    Minkoff, M.S.3    Balcewicz-Sablinska, M.K.4
  • 36
    • 0242501629 scopus 로고    scopus 로고
    • Thioredoxin reductase, a redox-active selenoprotein, is secreted by normal and neoplastic cells: Presence in human plasma
    • Soderberg A, Sahaf B, and Rosen A. Thioredoxin reductase, a redox-active selenoprotein, is secreted by normal and neoplastic cells: presence in human plasma. Cancer Res 60: 2281-2289, 2000.
    • (2000) Cancer Res , vol.60 , pp. 2281-2289
    • Soderberg, A.1    Sahaf, B.2    Rosen, A.3
  • 37
    • 0024461420 scopus 로고
    • ATL-derived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction
    • Tagaya Y, Maeda Y, Mitsui A, Kondo N, Matsui H, Hamuro J, Brown N, Arai K, Yokota T, Wakasugi H, and Yodoi J. ATL-derived factor (ADF), an IL-2 receptor/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction. EMBO J 8: 757-764, 1989.
    • (1989) EMBO J , vol.8 , pp. 757-764
    • Tagaya, Y.1    Maeda, Y.2    Mitsui, A.3    Kondo, N.4    Matsui, H.5    Hamuro, J.6    Brown, N.7    Arai, K.8    Yokota, T.9    Wakasugi, H.10    Yodoi, J.11
  • 39
    • 0036798783 scopus 로고    scopus 로고
    • Improperly folded green fluorescent protein is secreted via a non-classical pathway
    • Tanudji M, Hevi S, and Chuck SL. Improperly folded green fluorescent protein is secreted via a non-classical pathway. J Cell Sci 115:3849-3857, 2002.
    • (2002) J Cell Sci , vol.115 , pp. 3849-3857
    • Tanudji, M.1    Hevi, S.2    Chuck, S.L.3
  • 40
    • 0024653270 scopus 로고
    • Production of an IL-1-like factor by 3B6 EBV-infected B cells
    • Wakasugi H, Wakasugi N, Tursz T, Tagaya Y, and Yodoi J. Production of an IL-1-like factor by 3B6 EBV-infected B cells [letter]. J Immunol 142: 2569-2570, 1989.
    • (1989) J Immunol , vol.142 , pp. 2569-2570
    • Wakasugi, H.1    Wakasugi, N.2    Tursz, T.3    Tagaya, Y.4    Yodoi, J.5
  • 41
    • 0025066731 scopus 로고
    • Adult T-cell leukemia-derived factor/thioredoxin, produced by both human T-lymphotropic virus type I- and Epstein-Barr virus-transformed lymphocytes, acts as an autocrine growth factor and synergizes with interleukin 1 and interleukin 2
    • Wakasugi N, Tagaya Y, Wakasugi H, Mitsui A, Maeda M, Yodoi J, and Tursz T. Adult T-cell leukemia-derived factor/thioredoxin, produced by both human T-lymphotropic virus type I- and Epstein-Barr virus-transformed lymphocytes, acts as an autocrine growth factor and synergizes with interleukin 1 and interleukin 2. Proc Natl Acad Sci USA 87: 8282-8286, 1990.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8282-8286
    • Wakasugi, N.1    Tagaya, Y.2    Wakasugi, H.3    Mitsui, A.4    Maeda, M.5    Yodoi, J.6    Tursz, T.7
  • 42
    • 0030585429 scopus 로고    scopus 로고
    • Crystal structures of reduced, oxidized, and mutated human thioredoxins: Evidence for a regulatory homodimer
    • Weichsel A, Gasdaska JR, Powis G, and Montfort WR. Crystal structures of reduced, oxidized, and mutated human thioredoxins: evidence for a regulatory homodimer. Structure 4: 735-751, 1996.
    • (1996) Structure , vol.4 , pp. 735-751
    • Weichsel, A.1    Gasdaska, J.R.2    Powis, G.3    Montfort, W.R.4


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