메뉴 건너뛰기




Volumn 26, Issue 5, 1999, Pages 361-372

Complex interaction between HLA DR and DQ in conferring risk for childhood type 1 diabetes

Author keywords

[No Author keywords available]

Indexed keywords

HLA DQ ANTIGEN; HLA DR ANTIGEN;

EID: 0032851029     PISSN: 09607420     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2370.1999.00173.x     Document Type: Article
Times cited : (68)

References (86)
  • 1
    • 0026554270 scopus 로고
    • Genetic analysis of HLA class II alleles and susceptibility Type 1 (insulin-dependent) diabetes mellitus in Japanese subjects
    • Awata, T., Kuzuya, T., Matsuda, A., Iwamoto, Y. & Kanazawa, Y. (1992) Genetic analysis of HLA class II alleles and susceptibility Type 1 (insulin-dependent) diabetes mellitus in Japanese subjects. Diabetologia, 35, 419.
    • (1992) Diabetologia , vol.35 , pp. 419
    • Awata, T.1    Kuzuya, T.2    Matsuda, A.3    Iwamoto, Y.4    Kanazawa, Y.5
  • 4
    • 0025087080 scopus 로고
    • The HLA-DR4-associated DQw8 allele is confined to HLA-DR3/DR4 heterozygous type 1 (insulin-dependent) diabetics
    • Boehm, B.O., Schifferdecker, F., Rosak, C., Kuchol, P., Driesel, A.J. & Schöffling, K. (1991) The HLA-DR4-associated DQw8 allele is confined to HLA-DR3/DR4 heterozygous type 1 (insulin-dependent) diabetics. Tissue Antigens, 36, 81.
    • (1991) Tissue Antigens , vol.36 , pp. 81
    • Boehm, B.O.1    Schifferdecker, F.2    Rosak, C.3    Kuchol, P.4    Driesel, A.J.5    Schöffling, K.6
  • 6
    • 0027213991 scopus 로고
    • HLA-DQA1 and DQB1 gene polymorphisms in type 1 diabetic patients from central Italy and their use for risk prediction
    • Buzzetri, R., Nistico, L., Osborn, J.E., Giovannini, C., Chersi, A. & Sorrentino, R. (1993) HLA-DQA1 and DQB1 gene polymorphisms in type 1 diabetic patients from central Italy and their use for risk prediction. Diabetes, 42, 1173.
    • (1993) Diabetes , vol.42 , pp. 1173
    • Buzzetri, R.1    Nistico, L.2    Osborn, J.E.3    Giovannini, C.4    Chersi, A.5    Sorrentino, R.6
  • 9
    • 0027408095 scopus 로고
    • Both DQA1 and DQB1 genes are implicated in HLA-associated protection from type 1 (insulin-dependent) diabetes mellitus in a British Caucasian population
    • Cavan, D.A., Jacobs, K.H, Penny, M.A., Kelly, M.A., Mijovic, C., Jenkins, D., Fletcher, J.A. & Barnett, A.H. (1993) Both DQA1 and DQB1 genes are implicated in HLA-associated protection from type 1 (insulin-dependent) diabetes mellitus in a British Caucasian population. Diabetologia, 36, 252.
    • (1993) Diabetologia , vol.36 , pp. 252
    • Cavan, D.A.1    Jacobs, K.H.2    Penny, M.A.3    Kelly, M.A.4    Mijovic, C.5    Jenkins, D.6    Fletcher, J.A.7    Barnett, A.H.8
  • 11
    • 0028279896 scopus 로고
    • Comparative analysis of the genetic associations of HLA-DR3 and tumour necrosis factor alpha with human IDDM
    • Cox, A., Gonzalez, A.M., Wilson, A.G., Wilson, R.M., Ward, J.D., Artlett, C.M., Welsh, K. & Duff, G.W. (1994) Comparative analysis of the genetic associations of HLA-DR3 and tumour necrosis factor alpha with human IDDM. Diabetologia, 37, 500.
    • (1994) Diabetologia , vol.37 , pp. 500
    • Cox, A.1    Gonzalez, A.M.2    Wilson, A.G.3    Wilson, R.M.4    Ward, J.D.5    Artlett, C.M.6    Welsh, K.7    Duff, G.W.8
  • 15
    • 0024511641 scopus 로고
    • The Swedish childhood diabetes study-results from a nine year case register and one year case-referent study indicating that type 1 (insulin-dependent) diabetes mellitus is associated with both type 2 (non-insulin-dependent) diabetes mellitus and autoimmune disorders
    • Dahlquist, G., Blom, L., Tuvemo, T., Nyström, L., Sandstöm, A. & Wall, S. (1989) The Swedish Childhood Diabetes Study-results from a nine year case register and one year case-referent study indicating that type 1 (insulin-dependent) diabetes mellitus is associated with both type 2 (non-insulin-dependent) diabetes mellitus and autoimmune disorders. Diabetologia, 32, 2.
    • (1989) Diabetologia , vol.32 , pp. 2
    • Dahlquist, G.1    Blom, L.2    Tuvemo, T.3    Nyström, L.4    Sandstöm, A.5    Wall, S.6
  • 16
    • 0027787930 scopus 로고
    • Effects of various environmental stress paradigms and adrenalectomy on the expression of autoimmune type 1 diabetes in the non-obese diabetic (NOD) mouse
    • Durant, S., Coulaud, J., Amrani, A., El Hasnaoui, A., Dardenne, M. & Homo-Delarch, F. (1993) Effects of various environmental stress paradigms and adrenalectomy on the expression of autoimmune type 1 diabetes in the non-obese diabetic (NOD) mouse. Journal of Autoimmunity, 6, 735.
    • (1993) Journal of Autoimmunity , vol.6 , pp. 735
    • Durant, S.1    Coulaud, J.2    Amrani, A.3    El Hasnaoui, A.4    Dardenne, M.5    Homo-Delarch, F.6
  • 17
    • 0025318350 scopus 로고
    • HLA-DP-DQ and -DR RF1 P types in south Indian insulin-dependent diabetes mellitus patients
    • Easteal, S., Viswanathan, M. & Serjeantson, S.W. (1990) HLA-DP-DQ and -DR RF1 P types in south Indian insulin-dependent diabetes mellitus patients. Tissue Antigens, 35, 71.
    • (1990) Tissue Antigens , vol.35 , pp. 71
    • Easteal, S.1    Viswanathan, M.2    Serjeantson, S.W.3
  • 18
    • 85012537130 scopus 로고
    • HLA class II gene polymorphism, HLA typing, evolution and relationship to disease susceptibility
    • ed. by H.A. Erlich. Stockton Press, New York
    • Erlich, H.A. & Bugawan, B.L. (1989) HLA class II gene polymorphism, HLA typing, evolution and relationship to disease susceptibility. In: PCR Technology-Principles and Applications for DNA Amplification (ed. by H.A. Erlich), p. 193. Stockton Press, New York.
    • (1989) PCR Technology-Principles and Applications for DNA Amplification , pp. 193
    • Erlich, H.A.1    Bugawan, B.L.2
  • 21
    • 0027312972 scopus 로고
    • HLA-DQ beta typing and non-Asp57 alleles in IDDM and nondiabetic subjects in New Zealand
    • Forbes, L.V., Brown, L.J. & Scott, R.S. (1993) HLA-DQ beta typing and non-Asp57 alleles in IDDM and nondiabetic subjects in New Zealand. Diabetes Care, 16, 1179.
    • (1993) Diabetes Care , vol.16 , pp. 1179
    • Forbes, L.V.1    Brown, L.J.2    Scott, R.S.3
  • 24
    • 0001316449 scopus 로고
    • A simple exact test for birth-order effect
    • Haldane, J.B.S. & Smith, C.A.B, (1947) A simple exact test for birth-order effect. Annals of Eugenics, 14, 117.
    • (1947) Annals of Eugenics , vol.14 , pp. 117
    • Haldane, J.B.S.1    Smith, C.A.B.2
  • 25
    • 0030153435 scopus 로고    scopus 로고
    • Contribution of DRB1*04 variants to predisposition to or protection from insulin dependent diabetes mellitus is independent of dq
    • Harfouch, H.-E., Timsit, J., Boitard, C., Bach, J.F. & Caillat, Z.-S. (1996) Contribution of DRB1*04 variants to predisposition to or protection from insulin dependent diabetes mellitus is independent of dq. Journal of Autoimmunity, 9, 411.
    • (1996) Journal of Autoimmunity , vol.9 , pp. 411
    • Harfouch, H.-E.1    Timsit, J.2    Boitard, C.3    Bach, J.F.4    Caillat, Z.-S.5
  • 26
    • 0026521371 scopus 로고
    • Complementation of HLA-DQA and DQB genes confers susceptibility and protection to insulin-dependent diabetes mellitus
    • Heimberg, H., Nagy, Z.P., Somers, G., Deleeuw, I. & Schuit, F.C. (1992) Complementation of HLA-DQA and DQB genes confers susceptibility and protection to insulin-dependent diabetes mellitus. Human Immunology, 33, 10.
    • (1992) Human Immunology , vol.33 , pp. 10
    • Heimberg, H.1    Nagy, Z.P.2    Somers, G.3    Deleeuw, I.4    Schuit, F.C.5
  • 27
    • 0023706998 scopus 로고
    • The genetic susceptibility to IDDM in British and South Indian subjects
    • Hitman, G.A. & Mohan, V. (1988) The genetic susceptibility to IDDM in British and South Indian subjects. Biomedica Biochemica Acta, 47, 329.
    • (1988) Biomedica Biochemica Acta , vol.47 , pp. 329
    • Hitman, G.A.1    Mohan, V.2
  • 28
    • 0029620427 scopus 로고
    • HLA-encoded susceptibility to insulin-dependent diabetes mellitus is determined by DR and DQ genes as well as their linkage disequilibria in a Chinese population
    • Huang, H.S., Peng, J.T., She, J.Y., Zhang, L.P., Chao, C.C., Liu, K.H. & She, J.X. (1995) HLA-encoded susceptibility to insulin-dependent diabetes mellitus is determined by DR and DQ genes as well as their linkage disequilibria in a Chinese population. Human Immunology, 44, 210.
    • (1995) Human Immunology , vol.44 , pp. 210
    • Huang, H.S.1    Peng, J.T.2    She, J.Y.3    Zhang, L.P.4    Chao, C.C.5    Liu, K.H.6    She, J.X.7
  • 31
    • 0026092633 scopus 로고
    • Allele-specific gene probing supports the DQ molecule as a determinant of inherited susceptibility to Type 1 (insulin-dependent) diabetes mellitus
    • Jenkins, D., Mijovic, C., Jacobs, K.H., Penny, M.A., Fletcher, J. & Barnett, A.H. (1991a) Allele-specific gene probing supports the DQ molecule as a determinant of inherited susceptibility to Type 1 (insulin-dependent) diabetes mellitus. Diabetologia, 34, 109.
    • (1991) Diabetologia , vol.34 , pp. 109
    • Jenkins, D.1    Mijovic, C.2    Jacobs, K.H.3    Penny, M.A.4    Fletcher, J.5    Barnett, A.H.6
  • 32
    • 0025776206 scopus 로고
    • Tumour necrosis factor-beta polymorphism is unlikely to determine susceptibility to Type 1 (insulin-dependent) diabetes mellitus
    • Jenkins, D., Penny, M.A., Mijovic, C.H., Jacobs, K.H., Fletcher, J. & Barnett, A.H. (1991b) Tumour necrosis factor-beta polymorphism is unlikely to determine susceptibility to Type 1 (insulin-dependent) diabetes mellitus. Diabetologia, 34, 576.
    • (1991) Diabetologia , vol.34 , pp. 576
    • Jenkins, D.1    Penny, M.A.2    Mijovic, C.H.3    Jacobs, K.H.4    Fletcher, J.5    Barnett, A.H.6
  • 33
    • 0026641354 scopus 로고
    • Concordance for type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland
    • Kaprio, J., Tuomilehto, J., Koskenvuo, M., Romanov, K., Reunanen, A., Eriksson, J., Stengård, J. & Kesäniemi, Y.A. (1992) Concordance for type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland. Diabetologia, 35, 1060.
    • (1992) Diabetologia , vol.35 , pp. 1060
    • Kaprio, J.1    Tuomilehto, J.2    Koskenvuo, M.3    Romanov, K.4    Reunanen, A.5    Eriksson, J.6    Stengård, J.7    Kesäniemi, Y.A.8
  • 34
    • 0027359365 scopus 로고
    • Polymorphism of HSP70 gene is not associated with type 1 (insulin-dependent) diabetes mellitus in Japanese
    • Kawaguchi, Y., Ikegami, H., Fukuda, M., Fujioka, Y., Shima, K. & Ogihara, T. (1993) Polymorphism of HSP70 gene is not associated with type 1 (insulin-dependent) diabetes mellitus in Japanese. Diabetes Research, 21, 103.
    • (1993) Diabetes Research , vol.21 , pp. 103
    • Kawaguchi, Y.1    Ikegami, H.2    Fukuda, M.3    Fujioka, Y.4    Shima, K.5    Ogihara, T.6
  • 36
    • 0026547758 scopus 로고
    • Dose effect of cis- and trans-encoded HLA-DQ alpha beta heterodimers in IDDM susceptibility
    • Khalil, I., Deschamps I., Lepage, V., Al-Daccak, R., Degos, L. & Hors, J. (1992) Dose effect of cis- and trans-encoded HLA-DQ alpha beta heterodimers in IDDM susceptibility. Diabetes, 41, 378.
    • (1992) Diabetes , vol.41 , pp. 378
    • Khalil, I.1    Deschamps, I.2    Lepage, V.3    Al-Daccak, R.4    Degos, L.5    Hors, J.6
  • 37
    • 0022485271 scopus 로고
    • Evidence of an accelerated B-cell destruction in HLA-Dw3/Dw4 heterozygous children with Type 1 (insulin-dependent) diabetes
    • Knip, M., Honen, J., Mustonen, A. & Akerblom, H.K. (1986) Evidence of an accelerated B-cell destruction in HLA-Dw3/Dw4 heterozygous children with Type 1 (insulin-dependent) diabetes. Diabetologia, 29, 347.
    • (1986) Diabetologia , vol.29 , pp. 347
    • Knip, M.1    Honen, J.2    Mustonen, A.3    Akerblom, H.K.4
  • 38
    • 0027420431 scopus 로고
    • HLA-DQ primarily confers protection and HLA-DR susceptibility in Type 1 (insulin-dependent) diabetes studied in population-based affected families and controls
    • Kockum, I., Wassmuth, R., Holmberg, E., Michelsen, B. & Lernmark, Å. (1993) HLA-DQ primarily confers protection and HLA-DR susceptibility in Type 1 (insulin-dependent) diabetes studied in population-based affected families and controls. American Journal of Human Genetics, 53, 150.
    • (1993) American Journal of Human Genetics , vol.53 , pp. 150
    • Kockum, I.1    Wassmuth, R.2    Holmberg, E.3    Michelsen, B.4    Lernmark, Å.5
  • 39
    • 0028882717 scopus 로고
    • Population analysis of protection by HLA-DR and DQ genes from insulin-dependent diabetes mellitus in Swedish insulin-dependent diabetes children and controls
    • Kockum, I., Sanjeevi, C.B., Eastman, S., Landin-Olsson, M., Dahlquist, G. & Lernmark, Å. (1995) Population analysis of protection by HLA-DR and DQ genes from insulin-dependent diabetes mellitus in Swedish insulin-dependent diabetes children and controls. European Journal of Immunogenetics, 22, 443.
    • (1995) European Journal of Immunogenetics , vol.22 , pp. 443
    • Kockum, I.1    Sanjeevi, C.B.2    Eastman, S.3    Landin-Olsson, M.4    Dahlquist, G.5    Lernmark, Å.6
  • 40
    • 0027169651 scopus 로고
    • Genetic, etiological, and clinical significance of disease concordance according to age, zygosity, and the interval after diagnosis in first twin
    • Kumar, D., Gemayel, N.S., Deapen, D., Kapadia, D., Yamashita, P.H., Lee, M., Dwyer, J.H., Roy-Burman, P., Bray, G.A. & Mack, T.M, (1993) Genetic, etiological, and clinical significance of disease concordance according to age, zygosity, and the interval after diagnosis in first twin. Diabetes, 42, 1351.
    • (1993) Diabetes , vol.42 , pp. 1351
    • Kumar, D.1    Gemayel, N.S.2    Deapen, D.3    Kapadia, D.4    Yamashita, P.H.5    Lee, M.6    Dwyer, J.H.7    Roy-Burman, P.8    Bray, G.A.9    Mack, T.M.10
  • 41
    • 0025137159 scopus 로고
    • Sequence analysis of HLA-DR4B1 subtypes. Additional first domain variability is detected by oligonucleotide hybridization and nucleotide sequencing
    • Lanchbury, J.S.S., Hall, M.A., Welsh, K.I. & Panayi, G.S. (1990) Sequence analysis of HLA-DR4B1 subtypes. Additional first domain variability is detected by oligonucleotide hybridization and nucleotide sequencing. Human Immunology, 27, 136.
    • (1990) Human Immunology , vol.27 , pp. 136
    • Lanchbury, J.S.S.1    Hall, M.A.2    Welsh, K.I.3    Panayi, G.S.4
  • 42
    • 0026697868 scopus 로고
    • Predictive value of islet cell and insulin autoantibodies for type 1 (insulin-dependent) diabetes mellitus in a population-based study of newly-diagnosed diabetic and matched control children
    • Landin-Olsson, M., Palmer, J.P., Lernmark, Å., Blom, L., Sundkvist, G., Nyström, I., & Dahlquist, G. (1992) Predictive value of islet cell and insulin autoantibodies for type 1 (insulin-dependent) diabetes mellitus in a population-based study of newly-diagnosed diabetic and matched control children. Diabetologia, 35, 1068.
    • (1992) Diabetologia , vol.35 , pp. 1068
    • Landin-Olsson, M.1    Palmer, J.P.2    Lernmark, Å.3    Blom, L.4    Sundkvist, G.5    Nyström, I.6    Dahlquist, G.7
  • 43
    • 0025940819 scopus 로고
    • Analysis of HLA-DR and -DQ gene polymorphism in Sudanese patients with type 1 (insulin-dependent) diabetes
    • Magzoub, M.M.A., Stephens, H.A.F., Gale, E.A.M. & Bottazzo, G.F. (1991) Analysis of HLA-DR and -DQ gene polymorphism in Sudanese patients with type 1 (insulin-dependent) diabetes. Immunogenetics, 34, 366.
    • (1991) Immunogenetics , vol.34 , pp. 366
    • Magzoub, M.M.A.1    Stephens, H.A.F.2    Gale, E.A.M.3    Bottazzo, G.F.4
  • 46
    • 0017226637 scopus 로고
    • The estimability and estimation in case-referent studies
    • Miettinea, O.S. (1976) The estimability and estimation in case-referent studies. American Journal of Epidemiology, 103, 226.
    • (1976) American Journal of Epidemiology , vol.103 , pp. 226
    • Miettinea, O.S.1
  • 47
    • 0025778297 scopus 로고
    • HLA-DQA1 and -DQB1 alleles associated with genetic susceptibility to IDDM in Black populations
    • Mijovic, C.H., Jenkins, D., Jacobes, K.H., Penny, M.A., Fletcher, J.A. & Barnett, A.H. (1991) HLA-DQA1 and -DQB1 alleles associated with genetic susceptibility to IDDM in Black populations. Diabetes, 40, 748.
    • (1991) Diabetes , vol.40 , pp. 748
    • Mijovic, C.H.1    Jenkins, D.2    Jacobes, K.H.3    Penny, M.A.4    Fletcher, J.A.5    Barnett, A.H.6
  • 48
    • 0023239753 scopus 로고
    • HLA-DQw3.2 allele of the DR4 haplotype is associated with insulin-dependent diabetes; correlation between DQβ restriction fragments and DQβ chain variation
    • Monos, D.S., Speilman, R.S., Gogolin, K.J., Radka, S.F., Baker, L., Zmijewski, C.M. & Kamoun, M. (1987) HLA-DQw3.2 allele of the DR4 haplotype is associated with insulin-dependent diabetes; correlation between DQβ restriction fragments and DQβ chain variation. Immunogenetics, 26, 299.
    • (1987) Immunogenetics , vol.26 , pp. 299
    • Monos, D.S.1    Speilman, R.S.2    Gogolin, K.J.3    Radka, S.F.4    Baker, L.5    Zmijewski, C.M.6    Kamoun, M.7
  • 49
    • 0025131118 scopus 로고
    • A unified hypothesis for the complex genetics of HLA associations
    • Nepom, G.T. (1990) A unified hypothesis for the complex genetics of HLA associations. Diabetes, 39, 1153.
    • (1990) Diabetes , vol.39 , pp. 1153
    • Nepom, G.T.1
  • 51
    • 0031847984 scopus 로고    scopus 로고
    • Molecular basis for HLA-DQ associations with IDDM
    • Nepom, G.T. & Kwok, W.W. (1998) Molecular basis for HLA-DQ associations with IDDM. Diabetes, 47, 1177.
    • (1998) Diabetes , vol.47 , pp. 1177
    • Nepom, G.T.1    Kwok, W.W.2
  • 52
    • 0021038977 scopus 로고
    • Electrophoretic analysis of human HLA-DR antigens from HLA-DR4 homozygous cell lines. Correlation between β-chain diversity and HLA-D
    • Nepom, B.S., Nepom, G.T., Mickelson, E., Antonelli, P. & Ja, H. (1983) Electrophoretic analysis of human HLA-DR antigens from HLA-DR4 homozygous cell lines. Correlation between β-chain diversity and HLA-D. Proceedings of the National Academy of Sciences USA, 80, 6962.
    • (1983) Proceedings of the National Academy of Sciences USA , vol.80 , pp. 6962
    • Nepom, B.S.1    Nepom, G.T.2    Mickelson, E.3    Antonelli, P.4    Ja, H.5
  • 53
    • 0016177620 scopus 로고
    • HLA antigens and diabetes mellitus
    • Nerup, J., Platz, P. & Anderssen, O.O. (1974) HLA antigens and diabetes mellitus. Lancet, 2, 864.
    • (1974) Lancet , vol.2 , pp. 864
    • Nerup, J.1    Platz, P.2    Anderssen, O.O.3
  • 54
    • 0029953008 scopus 로고    scopus 로고
    • The role of HLA class II genes in insulin-dependent diabetes mellitus. Molecular analysis of 180 Caucasian, multiplex families
    • Noble, J.A., Valdes A.M., Cook, M., Klitz, W., Thomson, G. & Erlich, H.A. (1996) The role of HLA class II genes in insulin-dependent diabetes mellitus. Molecular analysis of 180 Caucasian, multiplex families. American Journal of Human Genetics, 59, 1134.
    • (1996) American Journal of Human Genetics , vol.59 , pp. 1134
    • Noble, J.A.1    Valdes, A.M.2    Cook, M.3    Klitz, W.4    Thomson, G.5    Erlich, H.A.6
  • 55
    • 0025234860 scopus 로고
    • The Swedish childhood diabetes study, an analysis of the temporal variation in diabetes incidence 1978
    • Nyström, L., Dahlquist, G., Rewers, M. & Wall, S. (1990) The Swedish childhood diabetes study, an analysis of the temporal variation in diabetes incidence 1978. International Journal of Epidemiology, 19, 141.
    • (1990) International Journal of Epidemiology , vol.19 , pp. 141
    • Nyström, L.1    Dahlquist, G.2    Rewers, M.3    Wall, S.4
  • 56
    • 0023634636 scopus 로고
    • The HLA-D associations of type 1 (insulin-dependent) diabetes in Punjabi Asians in the United Kingdom
    • Odugbesan, O., Fletcher, J., Mijovic, C., Mackay, E., Bradwell, A.R. & Barnett, A.H. (1987) The HLA-D associations of type 1 (insulin-dependent) diabetes in Punjabi Asians in the United Kingdom. Diabetologia, 30, 618.
    • (1987) Diabetologia , vol.30 , pp. 618
    • Odugbesan, O.1    Fletcher, J.2    Mijovic, C.3    Mackay, E.4    Bradwell, A.R.5    Barnett, A.H.6
  • 57
    • 0026691249 scopus 로고
    • HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours. An alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation
    • Olerup, O. & Zetterquist, H. (1992) HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2 hours. An alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigens, 39, 225.
    • (1992) Tissue Antigens , vol.39 , pp. 225
    • Olerup, O.1    Zetterquist, H.2
  • 58
    • 0020593780 scopus 로고
    • HLA-D region β-chain DNA endonuclease fragments differ between HLA-DR identical healthy and insulin-dependent diabetic individuals
    • Owerbach, D., Lernmark, Å., Platz, P., Ryder, L.P., Rask, L., Peterson, P.A. & Ludvigsson, J. (1983) HLA-D region β-chain DNA endonuclease fragments differ between HLA-DR identical healthy and insulin-dependent diabetic individuals. Nature, 303, 815.
    • (1983) Nature , vol.303 , pp. 815
    • Owerbach, D.1    Lernmark, Å.2    Platz, P.3    Ryder, L.P.4    Rask, L.5    Peterson, P.A.6    Ludvigsson, J.7
  • 59
    • 0023727736 scopus 로고
    • Oligonucleotide probes for HLA-DQA and DQB genes define susceptibility to Type 1 (insulin-dependent) diabetes mellitus
    • Owerbach, D., Gunn, S., Ty, G., Wible, L. & Gabbay, K.H. (1988) Oligonucleotide probes for HLA-DQA and DQB genes define susceptibility to Type 1 (insulin-dependent) diabetes mellitus. Diabetologia, 31, 751.
    • (1988) Diabetologia , vol.31 , pp. 751
    • Owerbach, D.1    Gunn, S.2    Ty, G.3    Wible, L.4    Gabbay, K.H.5
  • 60
    • 0024842071 scopus 로고
    • Primary association of HLA-DQw8 with type 1 diabetes in DR4 patients
    • Owerbach, D., Gunn, S. & Gabbay, K.H. (1989) Primary association of HLA-DQw8 with type 1 diabetes in DR4 patients. Diabetes, 38, 942.
    • (1989) Diabetes , vol.38 , pp. 942
    • Owerbach, D.1    Gunn, S.2    Gabbay, K.H.3
  • 65
    • 0024438233 scopus 로고
    • The amino acid at position 57 of the HLA-DQ beta chain and susceptibility to develop insulin-dependent diabetes mellitus
    • Rønningen, K.S., Iwe, T., Halstensen, T.S., Spurkland, A. & Thorsby, E. (1989) The amino acid at position 57 of the HLA-DQ beta chain and susceptibility to develop insulin-dependent diabetes mellitus. Human Immunology, 26, 215.
    • (1989) Human Immunology , vol.26 , pp. 215
    • Rønningen, K.S.1    Iwe, T.2    Halstensen, T.S.3    Spurkland, A.4    Thorsby, E.5
  • 66
    • 0025729141 scopus 로고
    • Distribution of HLA-DRB-DQA1 and -DQB1 alleles and DQA1-DQB1 genotypes among Norwegian patients with insulin-dependent diabetes mellitus
    • Rønningen, K.S., Sprukland, A., Iwe, T., Vartdal, F. & Thorsby, E. (1990) Distribution of HLA-DRB-DQA1 and -DQB1 alleles and DQA1-DQB1 genotypes among Norwegian patients with insulin-dependent diabetes mellitus. Tissue Antigens, 37, 105.
    • (1990) Tissue Antigens , vol.37 , pp. 105
    • Rønningen, K.S.1    Sprukland, A.2    Iwe, T.3    Vartdal, F.4    Thorsby, E.5
  • 69
    • 0026512196 scopus 로고
    • Different genetic background for Type 1 diabetes and malnutrition related diabetes in South Indians
    • Sanjeevi, C.B., Seshiah, V.M., Möller, E. & Olerup, O. (1992) Different genetic background for Type 1 diabetes and malnutrition related diabetes in South Indians. Diabetologia, 35, 283.
    • (1992) Diabetologia , vol.35 , pp. 283
    • Sanjeevi, C.B.1    Seshiah, V.M.2    Möller, E.3    Olerup, O.4
  • 75
    • 0015883122 scopus 로고
    • Histocompatibility (HL-A) antigens, lymphocytotoxic antibodies and tissue antibodies in patients with diabetes mellitus
    • Singal, D.P. & Blajchman, M.A. (1973) Histocompatibility (HL-A) antigens, lymphocytotoxic antibodies and tissue antibodies in patients with diabetes mellitus. Diabetes, 22, 429.
    • (1973) Diabetes , vol.22 , pp. 429
    • Singal, D.P.1    Blajchman, M.A.2
  • 76
    • 0024539633 scopus 로고
    • HLA and insulin-dependent diabetes. An overview
    • Svejgaard, A. & Ryder, L.P. (1989) HLA and insulin-dependent diabetes. An overview. Genetics Epidemiology, 6, 1.
    • (1989) Genetics Epidemiology , vol.6 , pp. 1
    • Svejgaard, A.1    Ryder, L.P.2
  • 77
    • 0023801542 scopus 로고
    • The susceptibility to insulin-dependent diabetes mellitus is associated with C4 allotypes independently of the association with HLA-DQ alleles in HLA-DR3, 4 heterozygotes
    • Thomsen, M., Molvig, J., Zerbib, A., De-Preval, C., Abbal, M., Dugoujon, J.M., Ohayon, E., Svejgaard, A., Cambon-Thomsen, A. & Nerup, J. (1988) The susceptibility to insulin-dependent diabetes mellitus is associated with C4 allotypes independently of the association with HLA-DQ alleles in HLA-DR3, 4 heterozygotes. Immunogenetics, 28, 320.
    • (1988) Immunogenetics , vol.28 , pp. 320
    • Thomsen, M.1    Molvig, J.2    Zerbib, A.3    De-Preval, C.4    Abbal, M.5    Dugoujon, J.M.6    Ohayon, E.7    Svejgaard, A.8    Cambon-Thomsen, A.9    Nerup, J.10
  • 78
    • 0021707829 scopus 로고
    • HLA DR antigens and susceptibility to insulin-dependent diabetes mellitus
    • Thomson, G. (1984) HLA DR antigens and susceptibility to insulin-dependent diabetes mellitus. American Journal of Epidemiology, 36, 1309.
    • (1984) American Journal of Epidemiology , vol.36 , pp. 1309
    • Thomson, G.1
  • 80
    • 0027238178 scopus 로고
    • Particular HLA DQ molecules play a dominant role in determining susceptibility or resistance to Type 1 (insulin-dependent) diabetes mellitus
    • Thorsby, K. & Rønningen, K.S. (1993) Particular HLA DQ molecules play a dominant role in determining susceptibility or resistance to Type 1 (insulin-dependent) diabetes mellitus. Diabetologia, 36, 371.
    • (1993) Diabetologia , vol.36 , pp. 371
    • Thorsby, K.1    Rønningen, K.S.2
  • 81
    • 0029022917 scopus 로고
    • Genetic analysis of type 1 diabetes using whole genome approaches
    • Todd, J.A. (1995) Genetic analysis of type 1 diabetes using whole genome approaches. Proceedings of the National Academy of Sciences USA, 92, 8560.
    • (1995) Proceedings of the National Academy of Sciences USA , vol.92 , pp. 8560
    • Todd, J.A.1
  • 82
    • 0023252262 scopus 로고
    • HLA DQ β gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus
    • Todd, J.A., Bell, J.I. & McDevitt, H.O. (1987) HLA DQ β gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus. Nature, 329, 599.
    • (1987) Nature , vol.329 , pp. 599
    • Todd, J.A.1    Bell, J.I.2    McDevitt, H.O.3
  • 83
    • 0024510601 scopus 로고
    • Identification of susceptibility loci for insulin-dependent diabetes mellitus by trans racial gene mapping
    • Todd, J.A., Mijovic, C., Fletcher, J., Jenkins, D., Bradwell, A.R. & Barnett, A.H. (1989) Identification of susceptibility loci for insulin-dependent diabetes mellitus by trans racial gene mapping. Nature, 338, 587.
    • (1989) Nature , vol.338 , pp. 587
    • Todd, J.A.1    Mijovic, C.2    Fletcher, J.3    Jenkins, D.4    Bradwell, A.R.5    Barnett, A.H.6
  • 85
    • 0029006991 scopus 로고
    • DRB1*0403 protects against IDDM in Caucasians with the high-risk heterozygous DQA1*0301-DQB1*0302/DQA1*0501-DQB1*0201 genotype. Belgian diabetes registry
    • Van der Auwera, B., Van, W.C., Schuit, E., Heimberg, H., Vandewalle, C., Gorus, F. & Flament, J. (1995) DRB1*0403 protects against IDDM in Caucasians with the high-risk heterozygous DQA1*0301-DQB1*0302/DQA1*0501-DQB1*0201 genotype. Belgian Diabetes Registry. Diabetes, 44, 527.
    • (1995) Diabetes , vol.44 , pp. 527
    • Van der Auwera, B.1    Van, W.C.2    Schuit, E.3    Heimberg, H.4    Vandewalle, C.5    Gorus, F.6    Flament, J.7
  • 86
    • 84960989652 scopus 로고
    • On estimating the relation between blood group and disease
    • Woolf, B. (1955) On estimating the relation between blood group and disease. Annals of Human Genetics, 19, 251.
    • (1955) Annals of Human Genetics , vol.19 , pp. 251
    • Woolf, B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.