Association of MHC Class I chain-related A (MIC-A) gene polymorphism with Type I diabetes

Diabetologia

Volumn 43, Issue 4, 2000, Pages 507-514

  Gambelunghe, G ^a   Ghaderi, M ^a   Cosentino, A ^b   Falorni, Ad ^b   Brunetti, P ^b   Falorni, Al ^b   Sanjeevi, C B ^a,c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF PERUGIA   (Italy)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Autoimmunity; Genetic risk; HLA; Insulin dependent diabetes; Major histocompatibility complex; TNFA gene

Indexed keywords

DNA; HLA ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ALLELE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0034056227     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001250051336     Document Type: Article

References (50)

1. Lernmark Å, Falorni A (1997) Immunology of insulin-dependent diabetes mellitus. In: Pickup J, Williams G (eds) Textbook of Diabetes. Blackwell Science, Oxford, pp 1-23
2. Sanjeevi CB, Kockum I, Lernmark Å (1995) The role of major histocompatibility complex in insulin dependent diabetes mellitus. Curr Opin Endocrinol Diabetes 2: 3-11
3. Nepom GT (1993) Immunogenetics and IDDM. Diabetes Rev 1: 93-103
4. Davies JL, Kawaguchi Y, Bennett ST et al. (1994) A genome-wide search for human type 1 diabetes susceptibility genes. Nature 371: 130-136
5. Hashimoto L, Habita C, Beressi J et al. (1994) Genetic mapping of a susceptibility locus for insulin-dependent diabetes mellitus on chromosome 11 q. Nature 371: 161-164
6. Field LL, Tobias R, Magnus T (1994) A locus on chromosome 15q26 (IDDM 3) produces susceptibility to insulin-dependent diabetes mellitus. Nat Genet 8: 189-194
7. Copeman JB, Cucca F, Herane CM et al. (1995) Linkage disequilibrium mapping of chromosome 6q in type 1 diabetes. Hum Mol Genet 5: 1071-1074
8. Owerbach D, Gabbay KH (1995) The HOXD8 locus (2q31) is linked to type 1 diabetes; interaction with chromosome 6 and 11 disease susceptibility genes. Diabetes 44: 132-136
9. Luo DF, Maclaren NK, Huang HS, Muir A, She JX (1995) Intrafamilial and case-control association analysis of D2S152 in insulin-dependent diabetes. Autoimmunity 21: 143-147
10. Zamani M, Pociot F, Raeymaekers P, Nerup J, Cassiman JJ (1996) Linkage of type I diabetes to 15q26 (IDDM 3) in the Danish population. Hum Genet 98: 491-496
11. Nisticò L, Buzzetti R, Pritchard LE et al. (1996) The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Hum Mol Genet 5: 1075-1080
12. Esposito L, Hill NJ, Pritchard LE et al. (1998) Genetic analysis of chromosome 2 in Type 1 diabetes. Analysis of putative loci IDDM7, IDDM12, and IDDM13 and candidate genes NRAMP1 and IA-2 and the interleukin-1 gene cluster. Diabetes 47: 1797-1799
13. Nerup J, Platz P, Anderssen OO (1974) HL-A antigens and diabetes mellitus. Lancet ii: 864-866
14. Singal DP, Blajchman MA (1973) Histocompatibility (HL-A) antigens, lymphocytotoxic antibodies and tissue antibodies in patients with diabetes mellitus. Diabetes 22: 429-432
15. Ronningen KS, Sprukland A, Iwe T, Vartdal F, Thorsby E (1991) Distribution of HLA-DRB, DQA1 and -DQB1 alleles and DQA1-DQB1 genotypes among Norwegian patients with insulin-dependent diabetes mellitus. Tissue Antigens 37: 105-111
16. Sanjeevi CB, Lybrand TP, DeWeese C et al. (1995) Polymorphic amino acid variations in HLA-DQ are associated with systematic property changes and occurrence of insulin-dependent diabetes mellitus. Diabetes 44: 125-131
17. She JX (1996) Susceptibility to type I diabetes: HLA-DQ and DR revisited. Immunol Today 17: 329-336
18. Pociot F, Briant L, Jongeneel CV et al. (1993) Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-alpha and TNF-beta by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus. Eur J Immunol 23: 224-231
19. Moghaddam P, Zwinderman A, de Knijff P et al. (1997) TNFa microsatellite polymorphism modulates the risk of IDDM in Caucasians with the high-risk genotype HLA DQA1*0501-DQB1*0201/DQA1*0301-DQB1*0302. Belgian Diabetes Registry. Diabetes 46: 1514-1515
20. Monos DS, Kamoun M, Udalova IA et al. (1995) Genetic polymorphism of the human tumor necrosis factor region in insulin-dependent diabetes mellitus. Linkage disequilibrium of TNFab microsatellite alleles with HLA haplotypes. Hum Immunol 44: 70-79
21. Bahram S, Bresnahan M, Geraghty DE, Spies T (1994) A second lineage of mammalian major histocompatibility complex class I genes. Proc Natl Acad Sci USA 91: 6259-6263
22. Bahram S, Spies T (1996) The MIC gene family. Rev Immunol 147: 328-333
23. Bahram S, Spies T (1996) Nucleotide sequence of a human MHC class I MICB cDNA. Immunogenetics 43: 230-233
24. Ota M, Katsuyama Y, Mizuki N et al. (1997) Trinucleotide repeat polymorphism within exon 5 of the MICA gene (MHC class I chain-related gene A): allele frequency data in the nine population groups Japanese, Northern Han, Hui, Uygur, Kazakhstan, Iranian, Saudi Arabian, Greek and Italian. Tissue Antigens 49: 448-454
25. Fodil N, Laloux L, Wanner Vet al. (1996) Allelic repertoire of the human MHC class I MICA gene. Immunogenetics 44: 351-357
26. Ricci Vitiani L, Potolicchio I, D'Amato M, Baricordi O, Sorrentino R (1998) MICA exon 5 microsatellite typing by DNA heteroduplex analysis: a new polymorphism in the transmembrane region. Tissue Antigens 51: 309-311
27. Mizuki N, Ota M, Kimura M et al. (1997) Trinucleotide repeat polymorphism in the transmembrane region of the MICA gene: a strong association of six GCT repetitions with Behçet's disease. Proc Natl Acad Sci USA 94: 1298-1303
28. Mizuki N, Ohno S, Sato T et al. (1995) Microsatellite polymorphism located between the TNF and HLA-B genes in Behcet's disease. Hum Immunol 43: 129-135
29. Yabuki K, Ota M, Goto K et al. (1999) Triplet repeat polymorphism in the MICA gene in HLA-B27 positive and negative Caucasian patients with ankylosing spondylitis. Hum Immunol 60: 83-86
30. Gambelunghe G, Falorni A, Ghaderi M et al. (1999) Microsatellite polymorphism of the MHC class I chain related (MIC-A and MIC-B) genes marks the risk for autoimmune Addison's disease. J Clin Endocrinol Metab 84: 3701-3707
31. National Diabetes Data Group (1979) Classification and diagnosis of diabetes mellitus and other categories of glucose intolerance. Diabetes 28: 1039-1049
32. Sanjeevi CB, Seshiah V, Möller E, Olerup O (1992) Different genetic background for Type I diabetes and malnutrition related diabetes in South Indians. Diabetologia 35: 283-286
33. Bunce M, O'Neill CM, Barnardo MCN et al. (1995) Phototyping: comprehensive DNA typing for HLA-A, B, C, DRB1, DRB3, DRB4, DRB5 6 DQB1 by PCR with 144 primer mixes utilizing sequence-specific primers (PCR-SSP). Tissue Antigens 46: 355-367
34. Nedospasov S, Udalova I, Kuprash D, Turetskaya R (1991) DNA sequence polymorphism at the human necrosis factor locus. J Immunol 147: 1053-1059
35. Woolf B (1955) On estimating the relation between blood group and disease. Ann Hum Genet 19: 251-253
36. Miettinen OS (1976) The estimability and estimation in case-referent studies. Am J Epidemiol 103: 226-235
37. Haldane S (1956) The estimation and significance of the logarithm of a ratio of frequencies. Ann Hum Genet. 20: 309-311
38. Svejgaard A, Ryder L (1994) HLA and disease associations: detecting the strongest association. Tissue Antigens 43: 18-27
39. Li P, Willie ST, Bauer S, Morris DL, Spies T, Strong RK (1999) Crystal structure of the MHC class I homolog MIC-A, a γδ T cell ligand. Immunity 10: 577-584
40. Zwirner N, Fernandez-Vina M, Statsny P (1998) MICA, a new polymorphic HLA-related antigen, is expressed main-ly by keratinocytes, endothelial cells, and monocytes. Immunogenetics 47: 139-148
41. Groh V, Steinle A, Bauer S, Spies T (1998) Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells. Science 279: 1737-1740
42. Degli-Esposti M, McCann V, Abraham L, Spies T, Christiansen F, Dawkins R (1992) Ancestral haplotypes reveal the role of the central MHC in the immunogenetics of IDDM. Immunogenetics 36: 345-356
43. Ando H, Mizuki N, Ota M et al. (1997) Allelic variants of the human MHC class I chain-related B gene (MICB). Immunogenetics 46: 499-508
44. Kimura T, Goto K, Yabuki K et al. (1998) Microsatellite polymorphism within the MICB gene among Japanese patients with Behçet's disease. Hum Immunol 59: 500-502
45. Shiina T, Tamiya G, Oka A et al. (1998) Nucleotide sequencing analysis of the 146-kilobase segment around the IkBL and MICA genes at the centromeric end of the HLA class I region. Genomics 47: 372-382
46. Illeni MT, Pellegris G, Del Guercio ML et al. (1977) HLA antigens in diabetic children. Diabetes 26: 870-873
47. Vardi P, Ziegler AG, Matthews JH et al. (1988) Concentration of insulin autoantibodies at onset of type I diabetes: inverse log-linear correlation with age. Diabetes Care 9: 736-739
48. Seissler J, de Sonnaville JJ, Morgenthaler NG et al. (1998) Immunological heterogeneity in Type I diabetes: presence of distinct autoantibody patterns in patients with acute onset and slowly progressive disease. Diabetologia 41: 891-897
49. Vandewalle CL, Falorni A, Svanholm S et al. (1995) High diagnostic sensitivity of glutamate decarboxylase autoantibodies in insulin-dependent diabetes mellitus with clinical onset between age 20 and 40 years. J Clin Endocrinol Metab 80: 846-851
50. Vandewalle CL, Decraene T, Schuit FC et al. (1993) Insulin autoantibodies and high titre islet cell antibodies are preferentially associated with the HLA-DQA1*0301-DQB1*0302 haplotype at clinical onset of Type I (insulin-dependent) diabetes before age 10 years but not at onset between age 10 and 40 years. Diabetologia 36: 1155-1162