메뉴 건너뛰기




Volumn 27, Issue 3, 2003, Pages 347-350

Effects of age and the CYP2D6*10 allele on the plasma haloperidol concentration/dose ratio

Author keywords

Age; Cytochrome P450 2D6; Haloperidol; Polymorphism

Indexed keywords

CYTOCHROME P450 2D6; HALOPERIDOL;

EID: 0037402520     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-5846(02)00314-7     Document Type: Article
Times cited : (15)

References (24)
  • 1
    • 0347063555 scopus 로고
    • Diagnostic and Statistical Manual of Mental Disorders, DSM-IV
    • American Psychiatric Association Diagnostic and Statistical Manual of Mental Disorders, DSM-IV. 4th ed. 1994.
    • (1994) 4th ed.
  • 2
    • 0036124107 scopus 로고    scopus 로고
    • CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants
    • Bradford L.D. CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics. 3:2002;229-243.
    • (2002) Pharmacogenomics , vol.3 , pp. 229-243
    • Bradford, L.D.1
  • 3
  • 5
    • 0028355764 scopus 로고
    • Drummer. Interpretation of a simple PCR analysis of the CYP 2D6(A) and CYP 2D6(B) null alleles associated with the debrisoquine/sparteine genetic polymorphism
    • Douglas A.M., Atchison B.A., Somogyi A.A., Olaf H. Drummer. Interpretation of a simple PCR analysis of the CYP 2D6(A) and CYP 2D6(B) null alleles associated with the debrisoquine/sparteine genetic polymorphism. Pharmacogenetics. 4:1994;154-158.
    • (1994) Pharmacogenetics , vol.4 , pp. 154-158
    • Douglas, A.M.1    Atchison, B.A.2    Somogyi, A.A.3    Olaf, H.4
  • 6
    • 0017327777 scopus 로고
    • Applied pharmacokinetics of haloperidol in man
    • Forsman A., Öhman R. Applied pharmacokinetics of haloperidol in man. Curr. Ther. Res. 21:1977;396-410.
    • (1977) Curr. Ther. Res. , vol.21 , pp. 396-410
    • Forsman, A.1    Öhman, R.2
  • 7
    • 0025080352 scopus 로고
    • Genotyping of poor metabolizers of debrisoquine by allele-specific PCR amplification
    • Heim M., Meyer U.A. Genotyping of poor metabolizers of debrisoquine by allele-specific PCR amplification. Lancet. 336:1990;529-532.
    • (1990) Lancet , vol.336 , pp. 529-532
    • Heim, M.1    Meyer, U.A.2
  • 8
    • 0034796765 scopus 로고    scopus 로고
    • Unravelling the functional genomics of the human CYP2D6 gene locus
    • Ingelman-Sundberg M., Evans W.E. Unravelling the functional genomics of the human CYP2D6 gene locus. Pharmacogenetics. 11:2001;553-554.
    • (2001) Pharmacogenetics , vol.11 , pp. 553-554
    • Ingelman-Sundberg, M.1    Evans, W.E.2
  • 9
    • 0027965620 scopus 로고
    • Genetic analysis of the Chinese cytochrome P4502D locus, characterization of variant CYP 2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation
    • Johansson I., Oscarson M., Yue Q.Y., Bertilsson L., Sjöqvist F., Ingelman-Sundberg M. Genetic analysis of the Chinese cytochrome P4502D locus, characterization of variant CYP 2D6 genes present in subjects with diminished capacity for debrisoquine hydroxylation. Mol. Pharmacol. 46:1994;452-459.
    • (1994) Mol. Pharmacol. , vol.46 , pp. 452-459
    • Johansson, I.1    Oscarson, M.2    Yue, Q.Y.3    Bertilsson, L.4    Sjöqvist, F.5    Ingelman-Sundberg, M.6
  • 10
    • 0020026653 scopus 로고
    • Haloperidol plasma level monitoring in neuropsychiatric patients
    • Morselli P.L., Bianchetti G., Dugas M. Haloperidol plasma level monitoring in neuropsychiatric patients. Ther. Drug Monit. 4:1982;51-58.
    • (1982) Ther. Drug Monit. , vol.4 , pp. 51-58
    • Morselli, P.L.1    Bianchetti, G.2    Dugas, M.3
  • 11
    • 0033821139 scopus 로고    scopus 로고
    • CYP 2D6 genotypes in a Japanese population, low frequencies of CYP 2D6 gene duplication but high frequency of CYP 2D6*10
    • Nishida Y., Fukuda T., Yamamoto I., Azuma J. CYP 2D6 genotypes in a Japanese population, low frequencies of CYP 2D6 gene duplication but high frequency of CYP 2D6*10. Pharmacogenetics. 10:2000;567-570.
    • (2000) Pharmacogenetics , vol.10 , pp. 567-570
    • Nishida, Y.1    Fukuda, T.2    Yamamoto, I.3    Azuma, J.4
  • 13
    • 0035464647 scopus 로고    scopus 로고
    • Plasma concentrations of haloperidol are related to CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patients
    • Roh H.K., Chung J.Y., Oh D.Y., Park C.S., Svensson J.O., Dahl M.L., Bertilsson L. Plasma concentrations of haloperidol are related to CYP2D6 genotype at low, but not high doses of haloperidol in Korean schizophrenic patients. Br. J. Clin. Pharmacol. 52:2001;265-271.
    • (2001) Br. J. Clin. Pharmacol. , vol.52 , pp. 265-271
    • Roh, H.K.1    Chung, J.Y.2    Oh, D.Y.3    Park, C.S.4    Svensson, J.O.5    Dahl, M.L.6    Bertilsson, L.7
  • 14
    • 0019405460 scopus 로고
    • Total and free serum haloperidol levels in schizophrenic patients and the effect of age, thioridazine and fatty acid on haloperidol-serum protein binding in vitro
    • Rowell J.F., Hui S.M., Fairbairn A.F., Eccleston D. Total and free serum haloperidol levels in schizophrenic patients and the effect of age, thioridazine and fatty acid on haloperidol-serum protein binding in vitro. Br. J. Clin. Pharmacol. 11:1981;377-382.
    • (1981) Br. J. Clin. Pharmacol. , vol.11 , pp. 377-382
    • Rowell, J.F.1    Hui, S.M.2    Fairbairn, A.F.3    Eccleston, D.4
  • 15
    • 0031038038 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 variants in a Caucasian population: Allele frequencies and phenotypic consequences
    • Sachse C., Brockmoller J., Bauer S., Roots I. Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences. Am. J. Hum. Genet. 60:1997;284-295.
    • (1997) Am. J. Hum. Genet. , vol.60 , pp. 284-295
    • Sachse, C.1    Brockmoller, J.2    Bauer, S.3    Roots, I.4
  • 17
    • 0033374688 scopus 로고    scopus 로고
    • Genetic association between cytochrome P-450 2D6 gene polymorphism and plasma concentration of haloperidol in Japanese schizophrenics
    • Shibata N., Ohnuma T., Baba H., Shimada H., Takahashi T., Arai H. Genetic association between cytochrome P-450 2D6 gene polymorphism and plasma concentration of haloperidol in Japanese schizophrenics. Psychiatr. Genet. 9:1999;145-148.
    • (1999) Psychiatr. Genet. , vol.9 , pp. 145-148
    • Shibata, N.1    Ohnuma, T.2    Baba, H.3    Shimada, H.4    Takahashi, T.5    Arai, H.6
  • 19
    • 0006820221 scopus 로고
    • Haloperidol and the geriatric patient, practical considerations
    • F.J. Ayd. Baltimore, MD: Ayd Medical Communications
    • Solomon K. Haloperidol and the geriatric patient, practical considerations. Ayd F.J. Haloperidol Update, 1950-1980. 1980;155-173 Ayd Medical Communications, Baltimore, MD.
    • (1980) Haloperidol Update, 1950-1980 , pp. 155-173
    • Solomon, K.1
  • 22
    • 0030826785 scopus 로고    scopus 로고
    • Effects of the CYP 2D6 genotype on the steady-state plasma concentrations of haloperidol and reduced haloperidol in Japanese schizophrenic patients
    • Suzuki A., Otani K., Mihara K., Yasui N., Kaneko S., Inoue Y., Hayashi K. Effects of the CYP 2D6 genotype on the steady-state plasma concentrations of haloperidol and reduced haloperidol in Japanese schizophrenic patients. Pharmacogenetics. 7:1997;415-418.
    • (1997) Pharmacogenetics , vol.7 , pp. 415-418
    • Suzuki, A.1    Otani, K.2    Mihara, K.3    Yasui, N.4    Kaneko, S.5    Inoue, Y.6    Hayashi, K.7
  • 23
    • 0031783832 scopus 로고    scopus 로고
    • In vivo age-related changes in hepatic drug-oxidizing capacity in humans
    • Tanaka E. In vivo age-related changes in hepatic drug-oxidizing capacity in humans. J. Clin. Pharmacol. Ther. 23:1998;247-255.
    • (1998) J. Clin. Pharmacol. Ther. , vol.23 , pp. 247-255
    • Tanaka, E.1
  • 24
    • 0033451187 scopus 로고    scopus 로고
    • Populations and genetic polymorphisms
    • Weber W.W. Populations and genetic polymorphisms. Mol. Diagn. 4:1999;299-307.
    • (1999) Mol. Diagn. , vol.4 , pp. 299-307
    • Weber, W.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.