A comparison between antisense p75(NTR) oligonucleotides and neurotrophic factors in promoting the survival of postnatal sensory neurons in vitro

In Vitro Cellular and Developmental Biology - Animal

Volumn 36, Issue 8, 2000, Pages 520-526

  Lowry, K S ^a   Cheema, S S ^a  

^a MONASH UNIVERSITY   (Australia)

Author keywords

Dorsal root ganglia; Low affinity neurotrophin receptor; Neurodegeneration; Neuronal cell death; Neuroprotection

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; LEUKEMIA INHIBITORY FACTOR; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; PROTEIN P75; ANTISENSE OLIGODEOXYNUCLEOTIDE; GROWTH INHIBITOR; INTERLEUKIN 6; LYMPHOKINE; NERVE GROWTH FACTOR RECEPTOR;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; COMPARATIVE STUDY; CONTROLLED STUDY; FEMALE; MALE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; RAT; SENSORY NERVE CELL; SPINAL GANGLION; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; PHYSIOLOGY; TIME; WISTAR RAT;

ANIMALIA;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; FEMALE; GANGLIA, SPINAL; GROWTH INHIBITORS; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; LYMPHOKINES; MALE; NERVE GROWTH FACTOR; NEURONS, AFFERENT; OLIGODEOXYRIBONUCLEOTIDES, ANTISENSE; RATS; RATS, WISTAR; RECEPTOR, NERVE GROWTH FACTOR; RECEPTORS, NERVE GROWTH FACTOR; TIME FACTORS;

EID: 0033625824     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: 10.1290/1071-2690(2000)036<0520:ACBAPN>2.0.CO;2     Document Type: Article

References (27)

1. The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death
2. The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development
3. The low-affinity nerve growth factor receptor p75NGFR mediates death of PC12 cells after nerve growth factor withdrawal
4. Rescue of dorsal root sensory neurons by nerve growth factor and neurotrophin-3, but not brain-derived neurotrophic factor or neurotrophin-4, is dependent on the level of the p75 neurotrophin receptor
5. Postnatal changes in the expression of the trkA high-affinity NGF receptor in primary sensory neurons
6. Effects of aging and axotomy on the expression of neurotrophin receptors in primary sensory neurons
7. Neuropeptides and neurotrophin receptor mRNAs in primary sensory neurons of aged rats
8. Purification of embryonic rat motoneurons by panning on a monoclonal antibody to the low-affinity NGF receptor
9. Dorsal root ganglion neurons expressing trk are selectively sensitive to NGF deprivation in utero
10. Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75
11. p75 Neurotrophin receptor as a modulator of survival and death decisions
12. Reducing p75 nerve growth factor receptor levels using antisense oligonucleotides prevents the loss of axotomized sensory neurons in the dorsal root ganglia of newborn rats
13. Leukemia inhibitory factor prevents the death of axotomised sensory neurons in the dorsal root ganglia of the neonatal rat
14. Leukemia inhibitory factor rescues motoneurons from axotomy-induced cell death
15. p75 Blockade - Can it prevent neuronal death?
16. Induction of cell death by endogenous nerve growth factor through its p75 receptor
17. Signal transduction by the neurotrophin receptors
18. Transgenic mice expressing the intracellular domain of the p75 neurotrophin receptor undergo neuronal apoptosis
19. Cholinergic differentiation factor (CDF/LIF) promotes survival of isolated rat embryonic motoneurons in vitro
20. Life and death decisions: A biological role for the p75 neurotrophin receptor
21. Neurotrophin receptor genes are expressed in distinct patterns in developing dorsal root ganglia
22. Generation of sensory neurons is stimulated by leukemia inhibitory factor
23. Induction of apoptosis by the low-affinity NGF receptor
24. NGF acts as a mediator of motoneuron cell death via the p75 receptor
25. The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons
26. Neurotrophin receptor mRNA expression defines distinct populations of neurons in rat dorsal root ganglia
27. Therapeutic potential of neurotrophic factors for neurological disorders