Active conductances in motoneuron dendrites enhance movement capabilities

Exercise and Sport Sciences Reviews

Volumn 31, Issue 2, 2003, Pages 96-101

  Heckman, C J ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Monoamines; Motor unit; Neuromodulation; Persistent inward current; Synaptic input

Indexed keywords

MONOAMINE;

ARTICLE; BRAIN STEM; DENDRITE; ELECTRIC POTENTIAL; EXERCISE; HUMAN; MOTONEURON; MOVEMENT (PHYSIOLOGY); NERVE CONDUCTION; NERVE FIBER; NERVE POTENTIAL; NEUROMODULATION; PRIORITY JOURNAL; SYNAPSE;

ACTION POTENTIALS; ANIMALS; BIOGENIC MONOAMINES; BRAIN STEM; COMPUTER SIMULATION; DECEREBRATE STATE; DENDRITES; HUMANS; MEMBRANE POTENTIALS; MOTOR NEURONS; SPINAL CORD;

EID: 0037391466     PISSN: 00916331     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003677-200304000-00008     Document Type: Article

References (15)

1. Alaburda, A., Perrier J.F., and J. Hounsgaard. Mechanisms causing plateau potentials in spinal motoneurones. Adv. Exp. Med. Biol. 508: 219-226, 2002.
2. Bennett, D.J., H. Hultborn, B. Fedirchuk, and M. Gorassini. Synaptic activation of plateaus in hindlimb motoneurons of decerebrate cats. J. Neurophysiol. 80:2023-2037, 1998.
3. Bennett, D.J., Y. Li, and M. Siu. Plateau potentials in sacrocaudal motoneurons of chronic spinal rats, recorded in vitro. J. Neurophysiol. 86:1955-1971, 2001.
4. Bradley, S.R., V.A. Pieribone, W. Wang, C.A. Severson, R.A. Jacobs, and G.B. Richerson. Chemosensitive serotonergic neurons are closely associated with large medullary arteries. Nat. Neurosci. 5:401-402, 2002.
5. Carlin, K.P., K.E. Jones, Z. Jiang, L.M. Jordan, and R.M. Brownstone. Dendritic L-type calcium currents in mouse spinal motoneurons: Implications for bistability. Eur. J. Neurosci. 12:1635-1646, 2000.
6. Collins, D.F., D. Burke, and S.C. Gandevia. Large involuntary forces consistent with plateau-like behavior of human motoneurons. J. Neurosci. 21:4059-4065, 2001.
7. Gorassini, M., J.F. Yang, M. Siu, and D.J. Bennett. Intrinsic activation of human motoneurons: reduction of motor unit recruitment thresholds by repeated contractions. J Neurophysiol. 87:1859-1866, 2002.
8. Heckman, C.J., and M.D. Binder. Computer simulation of the steady-state input-output function of the cat medial gastrocnemius motoneuron pool. J. Neurophysiol. 65:952-967, 1991.
9. Hornby, T.G., J.C. McDonagh, R.M. Reinking, and D.G. Stuart. Effects of excitatory modulation on intrinsic properties of turtle motoneurons. J. Neurophysiol. 88:86-97, 2002.
10. Hounsgaard, J., and O. Kiehn. Calcium spikes and calcium plateau evoked by differential polarization in dendrites of turtle motoneurones in vitro. J. Physiol. Lond. 468:245-259, 1993.
11. Jacobs, B.L., and C.A. Fornal. Serotonin and motor activity. Curr. Opin. Neurobiol. 7:820-825, 1997.
12. Kiehn, O., and T. Eken. Prolonged firing in motor units: evidence of plateau potentials in human motoneurons? J. Neurophysiol. 78:3061-3068, 1997.
13. Lee, R.H., and C.J. Heckman. Adjustable amplification of synaptic input in the dendrites of spinal motoneurons in vivo. J. Neurosci. 20: 6734-6740, 2000.
14. Powers, R.K., and M.D. Binder. Input-output functions of mammalian motoneurons. Rev. Physiol. Biochem. Pharmacol. 143:137-263, 2001.
15. Prather, J.F., R.K. Powers, and T.C. Cope. Amplification and linear summation of synaptic effects on motoneuron firing rate. J. Neurophysiol. 85:43-53, 2001.