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Volumn 32, Issue 4, 2003, Pages 427-433

Effect of simvastatin treatment on bone mineral density and bone turnover in hypercholesterolemic postmenopausal women: A 1-year longitudinal study

Author keywords

Bone mineral density; Bone turnover; Hypercholesterolemia; Osteoporosis; Statins

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM; COLLAGEN TYPE 1; LIPID; PHOSPHATE; SIMVASTATIN;

EID: 0037384716     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/S8756-3282(03)00034-6     Document Type: Article
Times cited : (125)

References (32)
  • 2
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: The Scandinavian simvastatin survival study (4S)
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease the Scandinavian simvastatin survival study (4S) . Lancet. 344:1994;1383-1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 3
    • 0028883828 scopus 로고
    • Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. WEST of Scotland coronary prevention study group
    • Shepherd J., Cobbe S.M., Ford I., Isles C.G., Lorimer A.R., Macfarlane P.W., McKillop J.H., Packard C.J. Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia. WEST of Scotland coronary prevention study group. N Engl J Med. 333:1995;1301-1307.
    • (1995) N Engl J Med , vol.333 , pp. 1301-1307
    • Shepherd, J.1    Cobbe, S.M.2    Ford, I.3    Isles, C.G.4    Lorimer, A.R.5    Macfarlane, P.W.6    McKillop, J.H.7    Packard, C.J.8
  • 4
    • 0032487931 scopus 로고    scopus 로고
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels
    • Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. N Engl J Med. 339:1998;1349-1357.
    • (1998) N Engl J Med , vol.339 , pp. 1349-1357
  • 7
    • 0000795922 scopus 로고    scopus 로고
    • Statins mediate their effects on osteoblasts by inhibition of HMG-CoA reductase and ultimately BMP-2
    • [Abstract]
    • Garrett I.R., Esparza J., Chen D., Zhao M., Gutierrez G., Escobado A., Horn D., Mundy G.R. Statins mediate their effects on osteoblasts by inhibition of HMG-CoA reductase and ultimately BMP-2. J Bone Miner Res. 15:(Suppl.1):2000;S225. [Abstract].
    • (2000) J Bone Miner Res , vol.15 , Issue.SUPPL.1 , pp. 225
    • Garrett, I.R.1    Esparza, J.2    Chen, D.3    Zhao, M.4    Gutierrez, G.5    Escobado, A.6    Horn, D.7    Mundy, G.R.8
  • 8
    • 0034805319 scopus 로고    scopus 로고
    • Simvastatin promotes osteoblast differentiation and mineralization in MC3T3-E1 cells
    • Maeda T., Matsunuma A., Kawane T., Horiuchi N. Simvastatin promotes osteoblast differentiation and mineralization in MC3T3-E1 cells. Biochem Biophys Res Commun. 280:2001;874-877.
    • (2001) Biochem Biophys Res Commun , vol.280 , pp. 874-877
    • Maeda, T.1    Matsunuma, A.2    Kawane, T.3    Horiuchi, N.4
  • 10
    • 0034685669 scopus 로고    scopus 로고
    • Compactin and simvastatina, but not pravastatin, induce bone morphogenetic protein 2 in human osteosarcoma cells
    • Sugiyama M., Kodama K., Konishi K., Abe K., Oikawa S. Compactin and simvastatina, but not pravastatin, induce bone morphogenetic protein 2 in human osteosarcoma cells. Biochem Biophys Res Commun. 271:2000;688-692.
    • (2000) Biochem Biophys Res Commun , vol.271 , pp. 688-692
    • Sugiyama, M.1    Kodama, K.2    Konishi, K.3    Abe, K.4    Oikawa, S.5
  • 11
    • 0033554651 scopus 로고    scopus 로고
    • Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates
    • van Beek E.J., Reekers J.A. Farnesyl pyrophosphate synthase is the molecular target of nitrogen-containing bisphosphonates. Biochem Biophys Res Commun. 264:1999;108-111.
    • (1999) Biochem Biophys Res Commun , vol.264 , pp. 108-111
    • Van Beek, E.J.1    Reekers, J.A.2
  • 12
    • 13044283050 scopus 로고    scopus 로고
    • Alendronate mechanism of action: Geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro
    • Fisher J.E., Rogers M.J., Halasy J.M., Luckman S.P., Hughes D.E., Masarachia P.J., Wesolowski G., Russell R.G., Rodan G.A., Reszka A.A. Alendronate mechanism of action geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro . Proc Natl Acad Sci USA. 96:1999;133-138.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 133-138
    • Fisher, J.E.1    Rogers, M.J.2    Halasy, J.M.3    Luckman, S.P.4    Hughes, D.E.5    Masarachia, P.J.6    Wesolowski, G.7    Russell, R.G.8    Rodan, G.A.9    Reszka, A.A.10
  • 13
    • 0031977199 scopus 로고    scopus 로고
    • Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational of GTP-binding proteins, including Ras
    • Luckman S.P., Hughes D.E., Coxon F.P., Graham R., Russell G., Rogers M.J. Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational of GTP-binding proteins, including Ras. J Bone Miner Res. 13:1998;581-589.
    • (1998) J Bone Miner Res , vol.13 , pp. 581-589
    • Luckman, S.P.1    Hughes, D.E.2    Coxon, F.P.3    Graham, R.4    Russell, G.5    Rogers, M.J.6
  • 17
    • 0034725357 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients
    • Wang P.S., Solomon D.H., Mogun H., Avorn J. HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients. JAMA. 283:2000;3211-3216.
    • (2000) JAMA , vol.283 , pp. 3211-3216
    • Wang, P.S.1    Solomon, D.H.2    Mogun, H.3    Avorn, J.4
  • 18
    • 0035901052 scopus 로고    scopus 로고
    • Effect of pravastatin on frequency of fracture in the LIPID study: Secondary analysis of a randomised controlled trial
    • Reid I.R., Hague W.H., Emberson J., Baker J., Tonkin A., Hunt D., Mac Mahon S., Sharpe N. Effect of pravastatin on frequency of fracture in the LIPID study secondary analysis of a randomised controlled trial . Lancet. 357:2001;509-512.
    • (2001) Lancet , vol.357 , pp. 509-512
    • Reid, I.R.1    Hague, W.H.2    Emberson, J.3    Baker, J.4    Tonkin, A.5    Hunt, D.6    Mac Mahon, S.7    Sharpe, N.8
  • 19
    • 0036164280 scopus 로고    scopus 로고
    • Hydroxymethylglutaryl-coenzyme A reductase inhibitors in osteoporosis management
    • Coons J.C. Hydroxymethylglutaryl-coenzyme A reductase inhibitors in osteoporosis management. Ann Pharmacother. 32:2002;326-330.
    • (2002) Ann Pharmacother , vol.32 , pp. 326-330
    • Coons, J.C.1
  • 20
    • 0033755942 scopus 로고    scopus 로고
    • Risk of hip fracture according to the World Health Organization criteria for osteopenia and osteoporosis
    • Kanis J.A., Johnell O., Oden A., Jonsson B., De Laet C., Dawson A. Risk of hip fracture according to the World Health Organization criteria for osteopenia and osteoporosis. Bone. 27:2000;585-590.
    • (2000) Bone , vol.27 , pp. 585-590
    • Kanis, J.A.1    Johnell, O.2    Oden, A.3    Jonsson, B.4    De Laet, C.5    Dawson, A.6
  • 22
    • 0034626389 scopus 로고    scopus 로고
    • Lack of positive correlation between statin use and bone mineral density in Japanese subjects with type 2 diabetes
    • Wada Y., Nakamura Y., Koshiyama H. Lack of positive correlation between statin use and bone mineral density in Japanese subjects with type 2 diabetes. Arch Intern Med. 160:2000;2865.
    • (2000) Arch Intern Med , vol.160 , pp. 2865
    • Wada, Y.1    Nakamura, Y.2    Koshiyama, H.3
  • 23
    • 0036190491 scopus 로고    scopus 로고
    • Geelog Osteoporosis Study. Statin use, bone mineral density, and fracture risk: Geelog osteoporosis study
    • Pasco J.A., Kotowicz M.A., Henry M.J., Sanders K.M., Nicholson G.C. Geelog Osteoporosis Study. Statin use, bone mineral density, and fracture risk Geelog osteoporosis study . Arch Intern Med. 162:2002;537-540.
    • (2002) Arch Intern Med , vol.162 , pp. 537-540
    • Pasco, J.A.1    Kotowicz, M.A.2    Henry, M.J.3    Sanders, K.M.4    Nicholson, G.C.5
  • 24
    • 0034957690 scopus 로고    scopus 로고
    • The effect of fluvastatin on parameters of bone remodeling
    • Bjarnason N.H., Riis B.J., Christiansen C. The effect of fluvastatin on parameters of bone remodeling. Osteoporos Int. 12:2001;380-384.
    • (2001) Osteoporos Int , vol.12 , pp. 380-384
    • Bjarnason, N.H.1    Riis, B.J.2    Christiansen, C.3
  • 26
    • 0034848003 scopus 로고    scopus 로고
    • Simvastatin increases serum osteocalcin concentration in patients treated for hypercholesterolemia
    • Chan M.H., Mak W.L., Chiu R.W., Chow C.C., Chan I.S., Lam C.K. Simvastatin increases serum osteocalcin concentration in patients treated for hypercholesterolemia. J Clin Endocrinol Metab. 86:2001;4556-4559.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4556-4559
    • Chan, M.H.1    Mak, W.L.2    Chiu, R.W.3    Chow, C.C.4    Chan, I.S.5    Lam, C.K.6
  • 27
    • 0030749322 scopus 로고    scopus 로고
    • Overview on bisphosphonates
    • Rogers M.G., Watts D.J., Russel R.G. Overview on bisphosphonates. Cancer. 80:(Suppl.8):1997;1652-1660.
    • (1997) Cancer , vol.80 , Issue.SUPPL.8 , pp. 1652-1660
    • Rogers, M.G.1    Watts, D.J.2    Russel, R.G.3
  • 28
    • 0012771918 scopus 로고    scopus 로고
    • The effects of statins on bone mineral density and quantitative bone histomorphometry in rodents
    • [Abstract]
    • Martiz F.J., Conradie M.M., Hulley P.A., Hough F.S. The effects of statins on bone mineral density and quantitative bone histomorphometry in rodents. Osteoporosis Int. 13:2002;S12. [Abstract].
    • (2002) Osteoporosis Int , vol.13 , pp. 12
    • Martiz, F.J.1    Conradie, M.M.2    Hulley, P.A.3    Hough, F.S.4
  • 30
    • 12944291524 scopus 로고    scopus 로고
    • Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral Efficacy with Risedronate Therapy (VERT) study group
    • Reginster J., Minne H.W., Sorensen O.H., Hooper M., Roux C., Brandi M.L., Lund B., Ethgen D., Pack S., Roumagnac I., Eastell R. Randomized trial of the effects of risedronate on vertebral fractures in women with established postmenopausal osteoporosis. Vertebral Efficacy with Risedronate Therapy (VERT) study group. Osterporos Int. 11:2000;83-91.
    • (2000) Osterporos Int , vol.11 , pp. 83-91
    • Reginster, J.1    Minne, H.W.2    Sorensen, O.H.3    Hooper, M.4    Roux, C.5    Brandi, M.L.6    Lund, B.7    Ethgen, D.8    Pack, S.9    Roumagnac, I.10    Eastell, R.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.