Arsenite-induced nitric oxide generation is cell cycle-dependent and aberrant in NBS cells

Toxicology in Vitro

Volumn 17, Issue 2, 2003, Pages 139-143

  Yuan, S S ^a   Hou, M F ^a   Chang, H L ^a   Chan, T F ^a   Wu, Y H ^a   Wu, Y C ^a   Su, J H ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Arsenite; Cell cycle; NBS1; Nitric oxide

Indexed keywords

ARSENIC TRIOXIDE; NITRIC OXIDE; PROTEIN; PROTEIN NSB1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; NIJMEGEN BREAKAGE SYNDROME; PROTEIN PHOSPHORYLATION;

EID: 0037376268     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0887-2333(02)00129-7     Document Type: Article

References (27)

1. Chen P.L., Scully P., Shew J.Y., Wang J.Y., Lee W.H. Phosphorylation of the retinoblastoma gene product is modulated during the cell cycle and cellular differentiation. Cell. 58:1989;1193-1198.
2. Cook J.A., Krishna M.C., Pacelli R., DeGraff W., Liebmann J., Mitchell J.B., Russo A., Wink D.A. Nitric oxide enhancement of melphalan-induced cytotoxicity. British Journal of Cancer. 76:1997;325-334.
3. Dasika G.K., Lin S.C., Zhao S., Sung P., Tomkinson A., Lee E.Y. DNA damage-induced cell cycle checkpoints and DNA strand break repair in development and tumorigenesis. Oncogene. 18:1999;7883-7899.
4. Gansauge S., Nussler A.K., Beger H.G., Gansauge F. Nitric oxide-induced apoptosis in human pancreatic carcinoma cell lines is associated with a G1-arrest and an increase of the cyclin-dependent kinase inhibitor p21WAF1/CIP1. Cell Growth and Differentiation. 9:1998;611-617.
5. Germolec D.R., Spalding J., Boorman G.A., Wilmer J.L., Yoshida T., Simeonova P.P., Bruccoleri A., Kayama F., Gaido K., Tennant R., Burleson F., Dong W., Lang R.W., Luster M.I. Arsenic can mediate skin neoplasia by chronic stimulation of keratinocyte-derived growth factors. Mutation Research. 386:1997;209-218.
6. Germolec D.R., Spalding J., Yu H.S., Chen G.S., Simeonova P.P., Humble M.C., Bruccoleri A., Boorman G.A., Foley J.F., Yoshida T., Luster M.I. Arsenic enhancement of skin neoplasia by chronic stimulation of growth factors. American Journal of Pathology. 153:1998;1775-1785.
7. Gonsebatt M.E., Vega L., Salazar A.M., Montero R., Guzman P., Blas J., Del Razo L.M., Garcia-Vargas G., Albores A., Cebrian M.E., Kelsh M., Ostrosky-Wegman P. Cytogenetic effects in human exposure to arsenic. Mutation Research. 386:1997;219-228.
8. Gurr J.R., Liu F., Lynn S., Jan K.Y. Calcium-dependent nitric oxide production is involved in arsenite-induced micronuclei. Mutation Research. 416:1998;137-148.
9. Hei T.K., Liu S.X., Waldren C. Mutagenicity of arsenic in mammalian cells. role of reactive species Proceedings of the National Academy of Sciences of the U.S.A. 95:1998;8103-8107.
10. Huang S.C., Huang C.Y., Lee T.C. Induction of mitosis-mediated apoptosis by sodium arsenite in HeLa S3 cells. Biochemical Pharmacology. 60:2000;771-780.
11. Jha A.N., Noditi M., Nilsson R., Natarajan A.T. Genotoxic effects of sodium arsenite on human cells. Mutation Research. 284:1992;215-221.
12. Kim P.K., Zamora R., Petrosko P., Billiar T.R. The regulatory role of nitric oxide in apoptosis. International Immunopharmacology. 1:2001;1421-1441.
13. Kolb J.P. Mechanisms involved in the pro- and anti-apoptotic role of NO in human leukaemia. Leukemia. 14:2000;1685-1694.
14. Lynn S., Shiung J.N., Gurr J.R., Jan K.Y. Arsenite stimulates poly(ADP-ribosylation) by generation of nitric oxide. Free Radical Biology and Medicine. 24:1998;442-449.
15. Moncada S., Higgs E.A. Molecular mechanisms and therapeutic strategies related to NO. FASEB Journal. 9:1995;1319-1330.
16. Moore L.E., Smith A.H., Hopenhayn-Rich C., Biggs M.L., Kalman D.A., Smith M.T. Decreased in bladder cell micronucleus prevalence after intervention to lower the concentration of arsenic in drinking water. Cancer Epidemiology, Biomarkers and Prevention. 12:1997;1051-1056.
17. Nguyen T., Brunson D., Crespi C.L., Penman B.W., Wishnok J.S., Tannenbaum S.R. DNA damage and mutation in human cells exposed to nitric oxide in vitro. Proceedings of the National Academy of Sciences of the USA. 89:1992;3030-3034.
18. Arsenic in Drinking Water. 1999;National Academy Press, Washington, DC.
19. Schmidt H.H. NO, CO and OH Endogenous soluble guanylyl cyclase-activating factors. FEBS Letters. 307:1992;102-107.
20. Simeonova P.P., Wang S., Toriuma W., Kommineni V., Matheson J., Unimye N., Kayama F., Harki D., Ding M., Vallyathan V., Luster M.I. Arsenic mediated cell proliferation and gene expression in the bladder epithelium. association with activating protein-1 transactivation Cancer Research. 60:2000;3445-3453.
21. Tanner F.C., Meier P., Greutert H., Champion C., Nabel E.G., Luscher T.F. Nitric oxide modulates expression of cell cycle regulatory proteins. a cytostatic strategy for inhibition of human vascular smooth muscle cell proliferation Circulation. 101:2000;1982-1989.
22. Takagi K., Isobe Y., Yasukawa K., Okouchi E., Suketa Y. Nitric oxide blocks the cell cycle of mouse macrophage-like cells in the early G2+M phase. FEBS Letters. 340:1994;159-162.
23. Trouba K.J., Wauson E.M., Vorce R.L. Sodium rsenite-induced dysregulation of proteins involved in proliferative signaling. Toxicology and Applied Pharmacology. 164:2000;161-179.
24. Xu W., Liu L., Smith G.C., Charles I.G. Nitric oxide upregulates expression of DNA-PKcs to protect cells from DNA-damaging anti-tumour agents. Nature Cell Biology. 2:2000;339-345.
25. Yamada K., Nabeshima T. Two pathways of nitric oxide production through glutamate receptors in the rat cerebellum in vivo. Neuroscience Research. 28:1997;93-102.
26. Yuan S.S., Lee S.Y., Chen G., Song M., Tomlinson G.E., Lee E.Y. BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo. Cancer Research. 59:1999;3547-3551.
27. Yuan S.S., Su J.H., Hou M.F., Yang F.W., Zhao S., Lee E.Y. Arsenic-induced Mre11 phosphorylation is cell cycle-dependent and defective in NBS cells. DNA Repair. 1:2002;137-142.