Bacterial multicellularity as a possible source of antibiotic resistance

Medical Hypotheses

Volumn 60, Issue 4, 2003, Pages 484-488

  Krasovec R ^a   Jerman, I ^a  

^a The Institute for Bioelectromagnetics and New Biology Ljubljana   (Slovenia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT;

ADAPTIVE BEHAVIOR; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL CELL; BACTERIAL MUTATION; BACTERIAL SURVIVAL; BACTERIUM MUTANT; BIOFILM; CELL COMMUNICATION; EVOLUTIONARY ADAPTATION; GENE CONTROL; GENE MUTATION; GENE TRANSFER; IN VITRO STUDY; MUTATION RATE; MUTATIONAL ANALYSIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STRESS;

BACTERIA (MICROORGANISMS);

EID: 0037375891     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-9877(02)00394-8     Document Type: Article

References (35)

1. Alonso A., Campanario E., Martinez J. L. Emergence of multidrug-resistant mutants is increased under antibiotic selective pressure in Pseudomonas aeruginosa. Microbiology (UK) 1999; 145: 2862-2875.
2. Bridges B. A. Hypermutation in bacteria and other cellular systems. Philos Trans R Soc Lond B 2001; 356: 29-39.
3. Cairns J., Foster P. L. Adaptive reversions of a frameshift mutation in Escherichia coli. Genetics 1991; 128: 695-701.
4. Cairns J., Overbaugh J., Miller S. The origin of mutants. Nature 1988; 335: 142-145.
5. Cavalli-Sforza L. L., Lederberg J. Isolation of pre-adaptive mutants in bacteria by sib selection. Genetics 1956; 41: 367-381.
6. Costerton J. W., Stewart P. S., Greenberg E. P. Bacterial biofilms: a common cause of persistent infections. Science 1999; 284: 1318-1322.
7. Costerton J. W., Cheng K. J., Geesey G. G. et al. Bacterial biofilms in nature and disease. Annu Rev Microbiol 1987; 41: 435-464.
8. Davies J. E. Origins, acquisition and dissemination of antibiotic resistance determinants. In: D. J. Chadwick, J. Goode (eds). Antibiotic Resistance: Origins, Evolution, Selection and Spread. New York: Wiley, 1997: 5-35.
9. Denamur E., Lecointre G., Darlu P. et al. Evolutionary implications of the frequent horizontal transfer of mismatch repair genes. Cell 2000; 103: 711-721.
10. Drake J. W. A constant rate of spontaneus mutation in DNA-based microbes. Proc Natl Acad Sci USA 1991; 88: 7160-7164.
11. Foster P. L. Adaptive mutation: implications for evolution. Bioessays 2000; 22: 1067-1074.
12. Foster P. L. Non-adaptive mutations occur on the F′ episome during adaptive mutation conditions in Escherichia coli. J Bacteriol 1997; 179: 1550-1554.
13. Foster P. L., Trimarchi J. M. Adaptive reversion of a frameshift mutation in Escherichia coli by simple base deletions in homopolymeric runs. Science 1994; 265: 407-409.
14. Godoy V. G., Fox M. S. Transposon stability and a role for conjugational transfer in adaptive mutability. Proc Natl Acad Sci USA 2000; 97: 7393-7398.
15. Hall B. G. Spectra of spontaneus growth-dependent and adaptive mutations at ebgR. J Bacteriol 1999; 181: 1149-1155.
16. Hall B. G. Spontaneous point mutations that occur more often when advantageous than when neutral. Genetics 1990; 126: 5-16.
17. Higgins N. P. Death and transfiguration among bacteria. Trends Biochem Sci 1992; 17: 207-211.
18. Kaiser D., Losick R. How and why bacteria talk to each other? Cell 1993; 73: 873-885.
19. Karunakaran P., Davies J. Genetic antagonism and hypermutability in Mycobacterium smegmatis. J Bacteriol 2000; 182: 3331-3335.
20. Kleerebezem M., Quadri L. E. Peptide pheromone-dependent regulation of antimicrobial peptide production in Gram-positive bacteria: a case of multicellular behavior. Peptides 2001; 22: 1579-1596.
21. Lederberg J., Lederberg E. M. Replica plating and indirect selection of bacterial mutants. J Bacteriol 1952; 63: 399-406.
22. Luria S. E., Delbrück M. Mutations of bacteria from virus sensitivity to virus resistance. Genetics 1943; 28: 491-511.
23. Maenhaut-Michel G., Blake C. E., Leach D. R. F., Shapiro J. A. Different structures of selected and unselected araB-lacZ fusions. Mol Microbiol 1997; 23: 1133-1145.
24. Mah T-F., O'Toole G. A. Mechanisms of biofilm resistance to antimicrobial agents. Trends Microbiol 2001; 9: 34-39.
25. Martinez J. L., Baquero F. Mutation frequencies and antibiotic resistance. Antimicrob Agents Chemother 2000; 44: 1771-1777.
26. Mckenzie G. J., Lee P. L., Lombardo M. J., Hastings P. J., Rosenberg S. M. SOS mutator DNA polymerase IV functions in adaptive mutation and not adaptive amplification. Mol Cell 2001; 7: 571-579.
27. Nikolaev Y. A. Distant interactions in bacteria. Microbiology 2000; 69: 497-503.
28. O'Toole G., Kaplan H. B., Kolter R. Biofilm formation as microbial development. Annu Rev Microbiol 2000; 54: 49-79.
29. Riesenfeld C., Everett M., Piddock L. J. V., Hall B. G. Adaptive mutations produce resistance to Ciprofloxacin. Antimicrob Agents Chemoter 1997; 41: 2059-2060.
30. Rosche W. A., Foster P. L. The role of transient hypermutators in adaptive mutation in Escherichia coli. Proc Natl Acad Sci USA 1999; 96: 6862-6867.
31. Rosenberg S. M. Evolving responsively: adaptive mutation. Nat Rev Genet 2001; 2: 504-515.
32. Rosenberg S. M., Longerich S., Gee P., Harris R. S. Adaptive mutation by deletions in small mono-nucleotide repeats. Science 1994; 265: 405-407.
33. Ruhfel R. E., Leonard B. A. B., Dunny G. M. Pheromone-inducible conjugation in Enterococcus faecalis: mating interactions mediated by chemical signals and direct contact. In: J. A. Shapiro, M. Dworkin (eds). Bacteria as Multicellular Organisms. New York: Oxford University Press, 1997: 53-68.
34. Stewart P. S., Costerton J. W. Antibiotic resistance of bacteria in biofilms. Lancet 2001; 358: 135-138.
35. Torkelson J., Harris R. S., Lombardo M. J., Nagendran J., Thulin C., Rosenberg S. M. Genome-wide hypermutation in a sub-population of stationary-phase cells underlies recombination-dependent adaptive mutation. EMBO J 1997; 16: 3303-3311.