Sugar derivatives as new 6-phosphogluconate dehydrogenase inhibitors selective for the parasite Trypanosoma brucei

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 7, 2003, Pages 1207-1214

  Pasti, Claudia ^a   Rinaldi, Eliana ^a   Cervellati, Carlo ^a   Dallocchio, Franco ^a   Hardré, Renaud ^b,c   Salmon, Laurent ^b   Hanau, Stefania ^a  

^a UNIVERSITY OF FERRARA   (Italy)

^b UNIVERSITÉ PARIS SACLAY   (France)

^c MASSEY UNIVERSITY   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

1,5 DIPHOSPHO DEXTRO RIBULOSE; 1,5 DIPHOSPHORIBITOL; 2 DEOXY 6 PHOSPHOGLUCONATE; 4 PHOSPHO DEXTRO ERYTHRONATE; 4 PHOSPHO DEXTRO ERYTHROSE; 5 DEOXY 5 PHOSPHONO DEXTRO ARABINONATE; 5 PHOSPHO DEXTRO ARABINO 1,4 LACTONE; 5 PHOSPHO DEXTRO ARABINOHYDRAZIDE; 5 PHOSPHO DEXTRO ARABINOHYDROXAMIC ACID; 5 PHOSPHO DEXTRO ARABINONAMIDE; 5 PHOSPHO DEXTRO ARABINONATE; 5 PHOSPHO DEXTRO ARABINOSE; 5 PHOSPHO DEXTRO RIBONATE; 6 DEOXY 6 PHOSPHONO DEXTRO GLUCONATE; 6 PHOSPHO DEXTRO GALACTONATE; 6 PHOSPHO DEXTRO MANNONATE; 6 PHOSPHOGLUCONATE DEHYDROGENASE INHIBITOR; 6,7 DIDEOXY 7 PHOSPHONO DEXTRO GLUCOHEPTANATE; ANTITRYPANOSOMAL AGENT; ENZYME INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ASSAY; CATALYSIS; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; LIVER; MICHAELIS CONSTANT; NONHUMAN; PARASITE; SHEEP; TRYPANOSOMA BRUCEI;

OVIS ARIES; TRYPANOSOMA; TRYPANOSOMA BRUCEI;

EID: 0037375853     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00650-8     Document Type: Article

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