Morphological and functional changes in cardiac myocytes isolated from mice overexpressing TNF-α

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 284, Issue 3 53-3, 2003, Pages

  Janczewski, Andrzej M ^a   Kadokami, Toshiaki ^a   Lemster, Bonnie ^a   Frye, Carole S ^a   McTiernan, Charles F ^a   Feldman, Arthur M ^a,b  

^a UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

Calcium; Echocardiography; Gender; Heart failure; Transgenic mice

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CALCIUM ION; FURA 2; ISOPRENALINE; MYOSIN HEAVY CHAIN; TUMOR NECROSIS FACTOR ALPHA;

AMPLITUDE MODULATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; CYTOKINE PRODUCTION; ECHOCARDIOGRAPHY; FEMALE; GENDER; GENE OVEREXPRESSION; HEART DILATATION; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE REMODELING; INOTROPISM; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; TRANSGENIC MOUSE;

EID: 0037372169     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.0718.2001     Document Type: Article

References (61)

1. Alloatti G, Penna C, De Martino A, Montrucchio G, and Camussi G. Role of nitric oxide and platelet-activating factor in cardiac alterations induced by tumor necrosis factor-α in the guinea-pig papillary muscle. Cardiovasc Res 41: 611-619, 1999.
2. Baig K, Mahon N, McKenna WJ, Caforio ALP, Bonow R, Francis GS, and Gheorghiade M. The pathophysiology of advanced heart failure. Am Heart J 35: S216-S230, 1998.
3. Beuckelmann DJ, Nabauer M, and Erdmann E. Intracellular calcium handling in isolated ventricular myocytes from patients with terminal heart failure. Circulation 85: 1046-1055, 1992.
4. Bonow RO. Left ventricular filling in ischemic and hypertrophic heart disease. In: Diastolic Relaxation of the Heart, edited by Grossman W and Lorell BH. Boston, MA: Nijhoff, 1988.
5. Bozkurt B, Kribbs SB, Clubb FJ, Michael LH, Didenko VV, Hornsby PJ, Seta Y, Oral H, Spinale FG, and Mann DL. Pathophysiologically relevant concentrations of tumor necrosis factor-α promote progressive left ventricular dysfunction and remodeling in rats. Circulation 97: 1382-1391, 1998.
6. Braunwald E and Bristow MR. Congestive heart failure: fifty years of progress. Circulation 102, Suppl 4: IV14-IV23, 2000.
7. Bryant D, Becker L, Richardson J, Shelton J, Franco F, Peshock R, Thompson M, and Giroir B. Cardiac failure in transgenic mice with myocardial expression of tumor necrosis factor-alpha. Circulation 97: 1375-1381, 1998.
8. Chien KR, Zhu H, Knowlton KU, Miller-Hance W, van Bilsen M, O'Brien TX, and Evans SM. Transcriptional regulation during cardiac growth and development. Annu Rev Physiol 55: 77-96, 1993.
9. 2+-ATPase gene in pressure overload-induced cardiac hypertrophy in the rat. Circ Res 66: 554-564, 1990.
10. Dipla K, Mattiello JA, Jeevanandam V, Houser SR, and Margulies KB. Myocyte recovery after mechanical circulatory support in humans with end-stage heart failure. Circulation 97: 2316-2322, 1998.
11. Dollery CM, McEwan JR, and Henney AM. Matrix metalloproteinases and cardiovascular disease. Circ Res 77: 863-868, 1995.
12. Douglas PS, Katz SE, Weinberg EO, Chen M, Bishop SP, and Lorell BH. Hypertrophic remodeling: gender differences in the early response to left ventricular pressure overload. J Am Coll Cardiol 32: 1118-1125, 1998.
13. Feldman AM, Weinberg EO, Ray PE, and Lorell BH. Selective changes in cardiac gene expression during compensated hypertrophy and the transition to cardiac decompensation in rats with chronic aortic banding. Circ Res 73: 184-192, 1993.
14. Finkel MS, Oddis CV, Jacob TD, Watkins SC, Hattler BG, and Simmons RL. Negative inotropic effects of cytokines on the heart mediated by nitric oxide. Science 257: 387-389, 1992.
15. Gerdes AM, Kellerman SE, Moore JA, Muffly KE, Clark LC, Reaves PY, Malec KB, McKeown PP, and Schocken DD. Structural remodeling of cardiac myocytes in patients with ischemic cardiomyopathy. Circulation 86: 426-430, 1992.
16. i and contractility in isolated adult rabbit ventricular myocytes. Am J Physiol Heart Circ Physiol 271: H1449-H1455, 1996.
17. Griffin M, Lee HW, Zhao L, and Eghbali-Webb M. Gender-related differences in proliferative response of cardiac fibroblasts to hypoxia: effects of estrogen. Mol Cell Biochem 215: 21-30, 2000.
18. Haghighi K, Schmidt AG, Hoit BD, Brittsan AG, Yatani A, Lester JW, Zhai J, Kimura Y, Dorn GW II, MacLennan DH, and Kranias EG. Superinhibition of sarcoplasmic reticulum function by phospholamban induces cardiac contractile failure. J Biol Chem 276: 24145-24152, 2000.
19. Hasenfuss G. Alterations of calcium-regulatory proteins in heart failure. Cardiovasc Res 37: 279-289, 1998.
20. 2+-ATPase in failing and nonfailing human myocardium. Circ Res 75: 434-442, 1994.
21. Hobai IA and O'Rourke B. Decreased sarcoplasmic reticulum calcium content is responsible for defective excitation-contraction coupling in canine heart failure. Circulation 103: 1577-1584, 2001.
22. Houser SR and Lakatta EG. Function of the cardiac myocyte in the conundrum of end-stage, dilated human heart failure. Circulation 99: 600-604, 1999.
23. Kadokami T, Frye C, Lemster B, Wagner CL, Feldman AM, and McTiernan CF. Anti-TNF-α antibody limits heart failure in a transgenic model. Circulation 104: 1094-1097, 2001.
24. Kadokami T, McTiernan CF, Kubota T, Frye CS, and Feldman AM. Sex-related survival differences in murine cardiomyopathy are associated with differences in TNF receptor expression. J Clin Invest 106: 589-597, 2000.
25. Komuro I and Yazaki Y. Control of cardiac gene expression by mechanical stress. Annu Rev Physiol 55: 55-75, 1993.
26. 2+ transients. FEBS Lett 376: 24-30, 1995.
27. Kruger C, Erdmann E, Nabauer M, and Beuckelmann DJ. Intracellular calcium handling in isolated ventricular myocytes from cardiomyopathic hamsters (strain BIO 14.6) with congestive heart failure. Cell Calcium 16: 500-508, 1994.
28. Kubota T, Bounoutas GS, Miyagishima M, Kadokami T, Sanders VJ, Bruton C, Robbins PD, McTiernan CF, and Feldman AM. Soluble tumor necrosis factor receptor abrogates myocardial inflammation but not hypertrophy in cytokine-induced cardiomyopathy. Circulation 101: 2518-2525, 2000.
29. Kubota T, McTiernan CF, Frye CS, Slawson SE, Lemster BH, Koretsky AP, Demetris AJ, and Feldman AM. Dilated cardiomyopathy in transgenic mice with cardiac-specific overexpression of tumor necrosis factor-α. Circ Res 81: 627-635, 1997.
30. Leri A, Malhotra A, Liew CC, Kajstura J, and Anversa P. Telomerase activity in rat cardiac myocytes is age and gender dependent. J Mol Cell Cardiol 32: 385-390, 2000.
31. Li YY, Feng YQ, Kadokami T, McTiernan CF, Draviam R, Watkins SC, and Feldman AM. Myocardial extracellular matrix remodeling in transgenic mice overexpressing tumor necrosis factor α can be modulated by anti-tumor necrosis factor α therapy. Proc Natl Acad Sci USA 97: 12746-12751, 2000.
32. Li YY, McTiernan CF, and Feldman AM. Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases and their regulators in cardiac matrix remodeling. Cardiovasc Res 46: 214-224, 2000.
33. 2+-ATPase in failing and nonfailing human hearts. Cardiovasc Res 31: 625-632, 1996.
34. 2+ exchange in the infracted heart. Implications for excitation-contraction coupling. Circ Res 81: 1083-1093, 1997.
35. Lompre AM, Schwartz K, d'Albis A, Lacombe G, Theim NV, and Swyaghedauw B. Myosin isoenzyme redistribution in chronic heart overload. Nature 282: 105-107, 1979.
36. Magid NR, Borer JS, Young MS, Wallerson DC, and De-Monteiro C. Suppression of protein degradation in progressive cardiac hypertrophy of chronic aortic regurgitation. Circulation 87: 1249-1257, 1993.
37. Malhotra A, Buttrick P, and Scheuer J. Effects of sex hormones on development of physiological and pathological cardiac hypertrophy in male and female rats. Am J Physiol Heart Circ Physiol 259: H866-H871, 1990.
38. Mann DL. Mechanisms and models in heart failure. A combinatory approach. Circulation 100: 999-1008, 1999.
39. Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, and Marks AR. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101: 365-376, 2000.
40. McCall E, Ginsburg KS, Bassani RA, Shannon TR, Qi M, Samarel AM, and Bers DM. Ca flux, contractility, and excitation-contraction coupling in hypertrophied rat ventricular myocytes. Am J Physiol Heart Circ Physiol 274: H1348-H1360, 1998.
41. McTiernan CF, Lemster BH, Frye CS, Combes A, and Feldman AM. Interleukin-1β inhibits phospholamban gene expression in cultured cardiomyocytes. Circ Res 81: 493-503, 1997.
42. 2+-ATPase in gene expression in the human ventricle during end-stage heart failure. J Clin Invest 85: 305-309, 1990.
43. Meyer M, Schillinger W, Pieske B, Holubarsch C, Heilmann C, Posival H, Kuwajima G, Mikoshiba K, Just H, and Hasenfuss G. Alterations of sarcoplasmic reticulum proteins in failing human dilated cardiomyopathy. Circulation 92: 778-784, 1995.
44. 2+-transporting ATPase, phospholamban, and calsequestrin levels in nonfailing and failing human myocardium. Circulation 90: 653-657, 1994.
45. Movsesian MA and Schwinger RHG. Calcium sequestration by the sarcoplasmic reticulum in heart failure. Cardiovasc Res 37: 352-359, 1998.
46. 2+-ATPase and phospholamban mRNA expression in response to pressure overload and thyroid hormone. Proc Natl Acad Sci USA 74: 555-564, 1994.
47. Nakao K, Minobe W, Roden R, Bristow MR, and Leinwand LA. Myosin heavy chain expression in human heart failure. J Clin Invest 100: 2362-2370, 1997.
48. 2+/calmodulin-dependent protein kinase is altered in heart failure. Circ Res 86: 596-605, 2000.
49. Olsson MC, Palmer BM, Leinwand LA, and Moore RL. Gender and aging in a transgenic mouse model of hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol 280: H1136-H1144, 2001.
50. Onodera T, Tamura T, Said S, McCune S, and Gerdes AM. Maladaptive remodeling of cardiac myocytes shape begins long before failure in hypertension. Hypertension 32: 753-757, 1998.
51. 2+-ATPase activity and phosphorylation level of phospholamban. Am J Physiol Heart Circ Physiol 277: H474-H480, 1999.
52. 2+-ATPase activity of cardiac sarcoplasmic reticulum from dilated cardiomyopathy patients compared with patients with nonfailing hearts. Circulation 92: 3220-3228, 1995.
53. Scheuer J, Malhotra A, Schaible TF, and Capasso J. Effects of gonadectomy and hormonal replacement on rat hearts. Circ Res 61: 12-19, 1987.
54. Shorofsky SR, Aggarwal R, Corretti M, Baffa JM, Strum JM, Al-Seikhan BA, Kobayashi YM, Jones LR, Wier WG, and Balke CW. Cellular mechanisms of altered contractility in the hypertrophied heart. Big hearts, big sparks. Circ Res 84: 424-434, 1999.
55. Sivasubramanian N, Coker ML, Kurrelmeyer KM, MacLellan WR, DeMayo FJ, Spinale FG, and Mann DL. Left ventricular remodeling in transgenic mice with cardiac restricted overexpression of tumor necrosis factor. Circulation 104: 826-831, 2001.
56. Weinberg EO, Thienelt CD, Katz SE, Bartunek J, Tajima M, Rohrbacj S, Douglas P, and Lorell BH. Gender differences in molecular remodeling in pressure overload hypertrophy. J Am Coll Cardiol 34: 264-273, 1999.
57. Wier WG, Egan TM, Lopez-Lopez JR, and Balke CW. Local control of excitation-contraction coupling in rat heart cells. J Physiol 474: 463-471, 1994.
58. Wolska BM and Solaro RJ. Method for isolation of adult mouse cardiac myocytes for studies of contraction and microfluorimetry. Am J Physiol Heart Circ Physiol 271: H1250-H1255, 1996.
59. + currents in adult mouse ventricular myocytes. J Gen Physiol 113: 661-677, 1999.
60. Yokoyama T, Nakano M, Bednarczyk JL, McIntyre BW, Entman M, and Mann DL. Tumor necrosis factor-α provokes a hypertrophic growth response in adult cardiac myocytes. Circulation 95: 1247-1252, 1999.
61. Yokoyama T, Vaca L, Rossen RD, Durante W, Hazarika P, and Mann DL. Cellular basis for negative inotropic effects of tumor necrosis factor-α in the adult mammalian heart. J Clin Invest 92: 2303-2312, 1993.