Endomorphin 2 analogues containing Dmp residue as an aromatic amino acid surrogate with high μ-opioid receptor affinity and selectivity

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 5, 2003, Pages 675-678

  Sasaki, Yusuke ^a   Sasaki, Ai ^a   Niizuma, Hideko ^a   Goto, Harumi ^a   Ambo, Akihiro ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2',6' DIMETHYLPHENYLALANINE; 2',6' DIMETHYLPHENYLALANINE PROLYLPHENYLALANYLPHENYLALANINAMIDE; AMINO ACID DERIVATIVE; AROMATIC AMINO ACID; DEXTRO 2',6' DIMETHYLPHENYLALANINE PROLYLPHENYLALANYLPHENYLALANINAMIDE; MORPHINE DERIVATIVE; MU OPIATE RECEPTOR; PHENYLALANINE; PHENYLALANYLPROLYLPHENYLALANYLPHENYLALANINAMIDE; POLYPEPTIDE; TYROSYLPROLINE 2',6' DIMETHYLPHENYLALANINE PHENYLALANINAMIDE; TYROSYLPROLINE DEXTRO 2',6' DIMETHYLPHENYLALANINE PHENYLALANINAMIDE; TYROSYLPROLYLPHENYLALANINE 2',6' DIMETHYLPHENYLALANINAMIDE; TYROSYLPROLYLPHENYLALANINE DEXTRO 2',6' DIMETHYLPHENYLALANINAMIDE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BINDING ASSAY; CONTROLLED STUDY; DATA ANALYSIS; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; ISOMER; NONHUMAN; PEPTIDE SYNTHESIS; RAT; RECEPTOR AFFINITY;

AMINO ACIDS, AROMATIC; ANALGESICS, OPIOID; ANIMALS; CHEMISTRY, PHYSICAL; GUINEA PIGS; MALE; MICE; MUSCLE CONTRACTION; OLIGOPEPTIDES; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; VAS DEFERENS;

EID: 0037356635     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00601-6     Document Type: Article

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