Palladium-catalyzed functionalization of 5- and 7-azaindoles

Tetrahedron Letters

Volumn 41, Issue 6, 2000, Pages 919-922

  Chi, Sung Min ^a   Choi, Joong Kwon ^a   Yum, Eul Kgun ^a,c   Chi, Dae Yoon ^b  

^a Korea Research Institute of Chemical Technology   (South Korea)

^b Inha University   (South Korea)

^c Chungnam National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

5 AZAINDOLE; 7 AZAINDOLE; INDOLE DERIVATIVE; PALLADIUM COMPLEX; UNCLASSIFIED DRUG;

ARTICLE; CATALYST; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS;

EID: 0000211617     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)02190-5     Document Type: Article

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27. The chloride and iodide were not separable by chromatography and the chloride was isolated after the coupling reaction. Three equivalents of fresh iodine monochloride were used. The reaction did not proceed in the presence of the hydroxymethyl or piperazinylethyl groups at the 3-position. For similar iododesilylation, see: Alimardanov, A.; Negishi, E.-i. Tetrahedron Lett. 1999, 40, 3839.