Protease-activated receptor (PAR)-independent growth and pro-inflammatory actions of thrombin on human cultured airway smooth muscle

British Journal of Pharmacology

Volumn 138, Issue 5, 2003, Pages 865-875

  Tran, Thai ^a   Stewart, Alastair G ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Airway; Granulocyte macrophage colony stimulating factor; Growth; Proliferation; Protease activated receptor; Smooth muscle; Thrombin

Indexed keywords

CALCIUM; CYCLIN D1; CYTOKINE; DEXTRO PHENYLALANYLPROLYLARGINYL CHLOROMETHYL KETONE; G PROTEIN COUPLED RECEPTOR; GLYCYLTYROSYLPROLYLGLYCYLGLUTAMINYLVALINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HIRUDIN; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE; PEPTIDE; PERTUSSIS TOXIN; PROTEINASE ACTIVATED RECEPTOR 1; PROTEINASE ACTIVATED RECEPTOR 2; PROTEINASE ACTIVATED RECEPTOR 3; PROTEINASE ACTIVATED RECEPTOR 4; PROTEINASE INHIBITOR; SDZ 217 766; SERYLLEUCYLISOLEUCYLGLYCYLLYSYLVALINE; THROMBIN; THROMBIN RECEPTOR ACTIVATING PEPTIDE 6; UNCLASSIFIED DRUG;

ARTICLE; BRONCHUS MUSCLE; CALCIUM CELL LEVEL; CELL PROLIFERATION; CONCENTRATION RESPONSE; CYTOKINE PRODUCTION; DESENSITIZATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MITOGENESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; RECEPTOR UPREGULATION;

BRONCHI; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; MUSCLE, SMOOTH; RECEPTOR, PAR-1; RECEPTORS, THROMBIN; THROMBIN;

EID: 0037349117     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705106     Document Type: Article

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