DNA injection in combination with electroporation: A novel method for vaccination of farmed ruminants

Scandinavian Journal of Immunology

Volumn 57, Issue 3, 2003, Pages 229-238

  Tollefsen, S ^a   Vordermeier, M ^b   Olsen, I ^c   Storset, A K ^d   Reitan, L J ^c   Clifford, D ^e   Lowrie, D B ^f   Wiker, H G ^g   Huygen, K ^h   Hewinson, G ^b   Mathiesen, I ^a   Tjelle, T E ^a  

^a UNIVERSITY OF OSLO   (Norway)

^b VETERINARY LABORATORIES AGENCY   (United Kingdom)

^c NORWEGIAN VETERINARY INSTITUTE   (Norway)

^d NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

^e Animal Services Unit New Haw   (United Kingdom)

^f NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^g NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

^h PASTEUR INSTITUTE OF BRUSSELS   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; HEAT SHOCK PROTEIN 65; MPB 70 ANTIGEN; MYCOBACTERIUM ANTIGEN; MYCOBACTERIUM ANTIGEN 85B; PLASMID DNA; UNCLASSIFIED DRUG;

ADOLESCENT; AGRICULTURE; ANIMAL CELL; ARTICLE; CATTLE; CATTLE DISEASE; CELLULAR IMMUNITY; CONTROLLED STUDY; DOMESTIC ANIMAL; ELECTROPORATION; FEMALE; GOAT; GOAT DISEASE; HUMORAL IMMUNITY; LOCAL ANESTHESIA; MALE; MUSCLE INJURY; NONHUMAN; PRIORITY JOURNAL; TUBERCULIN TEST; VACCINATION;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; BACTERIAL VACCINES; CATTLE; CHAPERONINS; ELECTROPORATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GOAT DISEASES; GOATS; IMMUNOLOGIC MEMORY; INTERFERON TYPE II; LYMPHOCYTE ACTIVATION; MALE; MYCOBACTERIUM BOVIS; TUBERCULIN TEST; TUBERCULOSIS, BOVINE; VACCINATION; VACCINES, DNA;

EID: 0037346983     PISSN: 03009475     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3083.2003.01218.x     Document Type: Article

References (45)

1. Steele JH. Regional and country status report. In: Thoen CO, Steele JH, eds. Mycobacterium bovis Infection in Animals and Human. Ames: Iowa States University Press, 1995, 169-72.
2. Krebs JR. Bovine tuberculosis in cattle and badgers. Ministry of Agriculture, Fisheries and Food Publications, London, UK, 1997.
3. Wedlock DN, Aldwell F, Collins DM, de Lisle GD, Wilson T, Buddle BM. Immune responses induced in cattle by virulent and attenuated Mycobacterium bovis strains: correlation of delayed-type hypersensitivity with ability of strains to grow in macrophages. Infect Immun 1999;67:2172-7.
4. Francis J. Bovine Tuberculosis. London: Staples Press, 1947, 157-81.
5. Vordermeier HM, Cockle PJ, Whelan AO et al. Effective DNA vaccination of cattle with the mycobacterial antigens MPB83 and MPB70 does not compromise the specificity of the comparative intradermal tuberculin skin test. Vaccine 2000;19:1246-55.
6. Tascon RE, Colston MJ, Ragno S, Stavropoulos E, Gregory D, Lowrie DB. Vaccination against tuberculosis by DNA injection. Nat Med 1996;2:888-92.
7. Lowrie DB, Tascon RE, Bonato VL et al. Therapy of tuberculosis in mice by DNA vaccination. Nature 1999;400:269-71.
8. Vordermeier HM, Whelan A, Cockle PJ, Farrant L, Palmer N, Hewinson RG. Use of synthetic peptides derived from the antigens ESAT-6 and CFP-10 for differential diagnosis of bovine tuberculosis in cattle. Clin Diagn Lab Immunol 2001;8:571-8.
9. Vordermeier HM, Cockle PJ, Whelan AO, Rhodes S, Hewinson RG. Toward the development of diagnostic assays to discriminate between Mycobacterium bovis infection and bacille Calmette-Guérin vaccination in cattle. Clin Infect Dis 2000;30 (Suppl. 3):S291-8.
10. Nagai S, Matsumoto J, Nagasuga T. Specific skin-reactive protein from culture filtrate of Mycobacterium bovis BCG. Infect Immun 1981;31:1152-60.
11. Wiker HG, Harboe M, Lea TE. Purification and characterization of two protein antigens from the heterogeneous BCG85 complex in Mycobacterium bovis BCG. Int Arch Allergy Appl Immunol 1986;81:298-306.
12. Huygen K, Content J, Denis O et al. Immunogenicity and protective efficacy of a tuberculosis DNA vaccine. Nat Med 1996;2:893-8.
13. Baldwin SL, D'Souza C, Roberts AD et al. Evaluation of new vaccines in the mouse and guinea pig model of tuberculosis. Infect Immun 1998;66:2951-9.
14. Kamath AT, Feng CG, Macdonald M, Briscoe H, Britton WJ. Differential protective efficacy of DNA vaccines expressing secreted proteins of Mycobacterium tuberculosis. Infect Immun 1999;67:1702-7.
15. Widera G, Austin M, Rabussay D et al. Increased DNA vaccine delivery and immunogenicity by electroporation in vivo. J Immunol 2000;164:4635-40.
16. Zucchelli S, Capone S, Fattori E et al. Enhancing B- and T-cell immune response to a hepatitis C virus E2 DNA vaccine by intramuscular electrical gene transfer. J Virol 2000;74:11598-607.
17. Kadowaki S, Chen Z, Asanuma H, Aizawa C, Kurata T, Tamura S. Protection against influenza virus infection in mice immunized by administration of hemagglutinin-expressing DNAs with electroporation. Vaccine 2000;18:2779-88.
18. Bachy M, Boudet F, Bureau M et al. Electric pulses increase the immunogenicity of an influenza DNA vaccine injected intramuscularly in the mouse. Vaccine 2001;19:1688-93.
19. Tollefsen S, Tjelle TE, Schneider J et al. Improved cellular and humoral immune responses against Mycobacterium tuberculosis antigens after intra-muscular DNA immunisation combined with muscle electroporation. Vaccine 2002;20:3370-8.
20. Lozes E, Huygen K, Content J et al. Immunogenicity and efficacy of a tuberculosis DNA vaccine encoding the components of the secreted antigen 85 complex. Vaccine 1997;15:830-3.
21. Wiker HG, Harboe M. The antigen 85 complex: a major secretion product of Mycobacterium tuberculosis. Microbiol Rev 1992;56:648-61.
22. Mathiesen I. Electropermeabilization of skeletal muscle enhances gene transfer in vivo. Gene Ther 1999;6:508-14.
23. Harris DP, Vordermeier HM, Friscia G et al. Genetically permissive recognition of adjacent epitopes from the 19-kDa antigen of Mycobacterium tuberculosis by human and murine T cells. J Immunol 1993;150:5041-50.
24. Vordermeier HM, Harris DP, Friscia G et al. T cell repertoire in tuberculosis: selective anergy to an immunodominant epitope of the 38-kDa antigen in patients with active disease. Eur J Immunol 1992;22:2631-7.
25. Wilkinson RJ, Vordermeier HM, Wilkinson KA et al. Peptide specific response to M. tuberculosis clinical spectrum, compartmentalization and effect of chemotherapy. J Infect Dis 1998;178:760-8.
26. van Drunen Littel-van den H, Braun RP, Lewis PJ et al. Intradermal immunization with a bovine herpesvirus-1 DNA vaccine induces protective immunity in cattle. J Gen Virol 1998;79:831-9.
27. European-Economic-Community. EEC Directive 80/219, Amending Directive 64/432, Annexe B. Official J 1980;L047:25-32.
28. Storset AK, Berntsen G, Larsen HJ. Kinetics of IL-2 receptor expression on lymphocyte subsets from goats infected with Mycobacterium avium subsp. paratuberculosis after specific in vitro stimulation. Vet Immunol Immunopathol 2000;77:43-54.
29. Zar JH. Biostatistical Analysis, 2nd edn. Englewood Cliffs, NJ: Prentice Hall, 1984.
30. Mir LM, Bureau MF, Gehl J et al. High-efficiency gene transfer into skeletal muscle mediated by electric pulses. Proc Natl Acad Sci USA 1999;96:4262-7.
31. Tanghe A, D'Souza S, Rosseels V et al. Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting. Infect Immun 2001;69:3041-7.
32. McShane H, Brookes R, Gilbert SC, Hill AV. Enhanced immunogenicity of CD4(+) T-cell responses and protective efficacy of a DNA-modified vaccinia virus Ankara prime-boost vaccination regimen for murine tuberculosis. Infect Immun 2001;69:681-6.
33. Feng CG, Palendira U, Demangel C, Spratt JM, Malin AS, Britton WJ. Priming by DNA immunization augments protective efficacy of Mycobacterium bovis bacille Calmette-Guérin against tuberculosis. Infect Immun 2001;69:4174-6.
34. Huygen K, Abramowicz D, Vandenbussche P et al. Spleen cell cytokine secretion in Mycobacterium bovis BCG-infected mice. Infect Immun 1992;60:2880-6.
35. Tollefsen S, Pollock JM, Lea T, Harboe M, Wiker HG. T- and B-cell epitopes in the secreted Mycobacterium bovis antigen Mpb70 in mice. Scand J Immunol 2003;57:151-61.
36. McNair J, Corbett DM, Girvin RM, Mackie DP, Pollock JM. Characterization of the early antibody response in bovine tuberculosis: MPB83 is an early target with diagnostic potential. Scand J Immunol 2001;53:365-71.
37. Newell DG, Clifton-Hadley RS, Cheeseman CL. The kinetics of serum antibody responses to natural infections with Mycobacterium bovis in one badger social group. Epidemiol Infect 1997;118:173-80.
38. Griffin JF, Nagai S, Buchan GS. Tuberculosis in domesticated red deer: comparison of purified protein derivative and the specific protein MPB70 for in vitro diagnosis. Res Vet Sci 1991;50:279-85.
39. Rhodes SG, Gavier-Widen D, Buddle BM et al. Antigen specificity in experimental bovine tuberculosis. Infect Immun 2000;68:2573-8.
40. Kim CH, Campbell DJ, Butcher EC. Nonpolarized memory T cells. Trends Immunol 2001;22:527-30.
41. Sallusto F, Lenig D, Forster R, Lipp M, Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999;401:708-12.
42. Wang X, Mosmann T. In vivo priming of CD4 T cells that produce interleukin (IL)-2 but not IL-4 or interferon (IFN)-gamma, and can subsequently differentiate into IL-4- or IFN-gamma-secreting cells. J Exp Med 2001;194:1069-80.
43. Davis HL, McCluskie MJ, Gerin JL, Purcell RH. DNA vaccine for hepatitis B: evidence for immunogenicity in chimpanzees and comparison with other vaccines. Proc Natl Acad Sci USA 1996;93:7213-8.
44. Wang R, Doolan DL, Le TP et al. Induction of antigen-specific cytotoxic T lymphocytes in humans by malaria DNA vaccine. Science 1998;282:476-80.
45. Rizzuto G, Cappelletti M, Malone D et al. Efficient and regulated erythropoietin production by naked DNA injection and muscle electroporation. Proc Natl Acad Sci USA 1999;96:6417-22.