Amphetamine increases aversive conditioning to diffuse contextual stimuli and to a discrete trace stimulus when conditioned at higher footshock intensity

Journal of Psychopharmacology

Volumn 17, Issue 1, 2003, Pages 67-76

  Norman, C ^a   Cassaday, H J ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Amphetamine; Contextual conditioning; Dopamine; Trace conditioning

Indexed keywords

AMPHETAMINE; DEXAMPHETAMINE;

ANIMAL EXPERIMENT; ARTICLE; AVERSION; CONTROLLED STUDY; DRUG EFFECT; LATENT INHIBITION; LEARNING; MALE; NOISE; NONHUMAN; PRIORITY JOURNAL; RAT; REINFORCEMENT; SHOCK; STIMULUS; TASK PERFORMANCE;

AMPHETAMINE; ANALYSIS OF VARIANCE; ANIMALS; AVOIDANCE LEARNING; CONDITIONING, CLASSICAL; DOPAMINE AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROSHOCK; MALE; NOISE; PHOTIC STIMULATION; RATS; RATS, WISTAR; REINFORCEMENT (PSYCHOLOGY);

EID: 0037346711     PISSN: 02698811     EISSN: None     Source Type: Journal    
DOI: 10.1177/0269881103017001701     Document Type: Article

References (45)

1. Baruch I, Hemsley D R, Gray J A (1988) Differential performance of acute and chronic schizophrenics in a latent inhibition task. J Nerv Mental Dis 176: 598-606
2. Buchel C, Dolan R, Armony J, Friston K (1999) Amygdala-hippocampal involvement in human aversive trace conditioning revealed through event related functional magnetic resonance imaging. J Neurosci 19: 10869-10876
3. Cassaday H J, Shilliam C S, Marsden C A (2001) Serotonergic depletion increases conditioned suppression to background stimuli in the rat. J Psychopharmacol 15: 83-92
4. DeVietti T L, Bauste R L, Nutt G, Barrett O V, Daly K, Petree A D (1987) Latent inhibition: a trace conditioning phenomenon? Learning Motivat 18: 185-201
5. Easterbrook J A (1959) The effects of emotion on cue utilization and the organisation of behavior. Psychol Rev 66: 183-199
6. Ellison GD, Eison MS (1983) Continuous amphetamine intoxication: an animal model of acute psychotic episode. Psychol Med 13: 751-761
7. Eysenck M W (1992) Anxiety: the cognitive perspective. Lawrence Erlbaum Associates Ltd, London
8. Feldon J, Shofel A, Weiner I (1990) Latent inhibition is unaffected by direct dopamine agonists. Pharmacol Biochem Behav 38: 309-314
9. Gray J A, Feldon J, Rawlins J N P, Hemsley D R, Smith A D (1991) The neuropsychology of schizophrenia. Behav Brain Sci 14: 1-84
10. Gray J A, Moran P M, Grigoryan G, Peters S L, Young A M J, Joseph M H (1997) Latent inhibition: the nucleus accumbens connection revisited. Behav Brain Res 88: 27-34
11. Gray N S, Pickering A D, Hemsley D R, Dawling S, Gray J A (1992) Abolition of latent inhibition by a single 5 mg dose of D-amphetamine in man. Psychopharmacology 107: 425-430
12. Gray N S, Williams J, Fernandez M, Ruddle R A, Good M A, Snowden R J (2001) Context dependent latent inhibition in adult humans. Quart J Exp Psychol 54B: 233-245
13. Groves P M, Rebec G V (1976) Biochemistry and behaviour: Some central actions of amphetamines and antipsychotic drugs. Ann Rev Psychol 27: 91-127
14. Hall G, Honey R C (1989) Contextual effects in conditioning, latent inhibition, and habituation: associative and retrieval functions of contextual cues. J Exp Psychol Animal Behav Proc 15: 232-241
15. Hellman P A, Crider A, Solomon P (1983) Interaction of tail pressure stress and d-amphetamine in disruption of the rat's ability to ignore an irrelevant stimulus. Behav Neurosci 97: 1017-1021
16. Howell D C (2002) Statistical methods for psychology, 5th edn, pp. 375-377. Duxbury Press, Belmont, CA
17. Joseph M H, Peters S L, Gray J A (1993) Nicotine blocks latent inhibition in rats: evidence for a critical role of increased functional activity of dopamine in the mesolimbic system at conditioning rather than pre-exposure. Psychopharmacology 110: 187-192
18. Joseph M H, Peters S L, Moran P M, Grigoryan G A, Young A M J, Gray J A (2000) Modulation of latent inhibition in the rat by altered dopamine transmission in the nucleus accumbens at the time of conditioning. Neuroscience 101: 921-930
19. Joyce E M, Iversen S D (1984) Dissociable effects of 6-OHDA- induced lesions of neostriatum on anorexia, locomotor activity and stereotypy: the role of behavioural competition, Psychopharmacology 83: 363-366
20. Kamin L J (1965) Temporal and intensity characteristics of the conditioned stimulus. In Prokasy W F (ed.), Classical conditioning: a symposium. Appleton-Century-Crofts, New York
21. Kelleher R T, Morse W H (1968) Determinants of the specificity of behavioural effects of drugs. Ergebnisse Physiol 60: 1-56
22. Keogh E, French C (1999) The effect of trait anxiety and mood manipulation on the breadth of attention. Eur J Personality 13: 209-223
23. Killcross A S, Robbins T W (1993) Differential effects of intraaccumbens and systemic amphetamine in latent inhibition using an on-baseline, within subjects conditioned suppression paradigm. Psychopharmacology 110: 479-489
24. Killcross A S, Dickinson A, Robbins T W (1994) Amphetamine- induced disruptions of latent inhibition are reinforcer mediated: implications for animal models of schizophrenic attentional dysfunction. Psychopharmacology 115: 185-195
25. Kumari V, Cotter P A, Mulligan, Checkley S A, Gray N S, Hemsley D R, Thornton J C, Corr P J, Toone B K, Gray J A (1999) Effects of D-amphetamine and haloperidol on latent inhibition in healthy male volunteers, J Psychopharmacol 13: 398-405
26. Lovibond P F, Preston G C, Mackintosh N J (1984) Context specificity of conditioning, extinction, and latent inhibition, J Exp Psychol Animal Behav Proc 10: 360-375
27. Lubow R E (1973) Latent inhibition. Psychol Bull 79: 398-407
28. Odling-Smee F J (1978) The overshadowing of background stimuli: some effects of varying amounts of training and UCS intensity. Quart J Exp Psychol 30: 737-746
29. O'Tuathaigh C M P, Moran P M (2002) Evidence for dopamine D1 receptor involvement in the stimulus selection task. Overshadowing in the rat. Psychopharmacology 162: 225-231
30. Peters S L, Joseph M H (1993) Haloperidol potentiation of latent inhibition in rats: evidence for a critical role at conditioning rather than pre-exposure. Behav Pharmacol 4: 183-186
31. Rawlins J N P, Feldon J, Salmon P, Gray J A, Garrud P (1980) The effects of chlordiazepoxide HCl administration upon punishment and conditioned suppression in the rat. Psychopharmacology 70: 317-322
32. Rawlins J N P, Tanner J (1998) The effects of hippocampal aspiration lesions on conditioning to the CS and to a background stimulus in trace conditioned suppression. Behav Brain Res 91: 61-72
33. Reidel G, Harrington N R, Hall G, MacPhail E M (1997) Nucleus accumbens lesions impair context, but not cue conditioning in rats. Neuroreport 8: 2477-2482
34. Solomon P, Schaaf E (1986) Hippocampus and trace conditioning of the rabbit's classically conditioned nictating membrane response. Behav Neurosci 100: 729-744
35. Solomon P R, Crider A, Winkelman J W, Turi A, Kamer R M, Kaplan L J (1981) Disrupted latent inhibition in the rat with chronic amphetamine or haloperidol-induced supersensitivity: relationship to schizophrenic attention disorder. Biol Psychiatry 17: 743-756
36. Tanner J, Rawlins J N P, Mellanby J H (1987) Manipulation of CS- US conditional probability and of the CS-US trace interval on conditioning to the CS and to a background stimulus in a CER situation. Learning Motivat 18: 371-391
37. Tsaltsas E, Schugens M M, Gray J A (1989) Effects of lesions of the dorsal noradrenergic bundle on conditioned suppression to a CS and to a contextual background stimulus. Behav Brain Res 31: 243-256
38. Warburton E C, Mitchell S N, Joseph M H (1996) Calcium dependent dopamine release in the rat nucleus accumbens following amphetamine challenge: implications for the disruption of latent inhibition. Behav Pharmacol 7: 119-129
39. Weiner I (1990) Neural substrates of latent inhibition: the switching model. Psychol Bull 108: 442-461
40. Weiner I, Feldon J (1997) The switching model of latent inhibition: an update of neural substrates. Behav Brain Res 88: 11-25
41. Weiner I, Lubow R E, Feldon J (1981) Chronic amphetamine and latent inhibition. Behav Brain Res 2: 285-286
42. Weiner I, Israeli-Telerant A, Feldon J (1987) Latent inhibition is not affected by acute or chronic administration of 6 mg/kg dl-amphetamine. Psychopharmacology 91: 345-351
43. Weiner I, Lubow R E, Feldon J (1988) Disruption of latent inhibition by acute administration of low doses of amphetamine. Pharmacol Biochem Behav 30: 871-878
44. Weiner I, Tarrasch R, Bernasconi E, Broersen L M, Ruttimann T C, Feldon J (1997) Amphetamine-induced disruption of latent inhibition is not reinforcer mediated. Pharmacol Biochem Behav 56: 817-826
45. Winocur G, Rawlins J N P, Gray J A (1987) The hippocampus and conditioning to contextual cues. Behav Neurosci 101: 617-625