Modulation of latent inhibition in the rat by altered dopamine transmission in the nucleus accumbens at the time of conditioning

Neuroscience

Volumn 101, Issue 4, 2000, Pages 921-930

  Joseph, M H ^a   Peters, S L ^a   Moran, P M ^a   Grigoryan, G A ^a   Young, A M J ^a   Gray, J A ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

Amphetamine; Dopamine; Haloperidol; Latent inhibition; Learned association; Nucleus accumbens

Indexed keywords

AMPHETAMINE; DOPAMINE; HALOPERIDOL; OXIDOPAMINE;

ANIMAL EXPERIMENT; ARTICLE; CONDITIONING; CONTROLLED STUDY; DOPAMINERGIC TRANSMISSION; LATENT INHIBITION; MALE; NEUROTRANSMITTER RELEASE; NONHUMAN; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; RAT;

AMPHETAMINE; ANIMALS; ASSOCIATION LEARNING; BEHAVIOR, ANIMAL; BRAIN DISEASES; CONDITIONING (PSYCHOLOGY); DOPAMINE; DOPAMINE ANTAGONISTS; DOPAMINE UPTAKE INHIBITORS; HALOPERIDOL; INJECTIONS; INJECTIONS, INTRAPERITONEAL; MALE; NEURAL INHIBITION; NUCLEUS ACCUMBENS; OXIDOPAMINE; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; SYNAPTIC TRANSMISSION;

EID: 0034736217     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00437-1     Document Type: Article

References (51)

1. A comparison of the effects of amphetamine, strychnine and caffeine on prepulse inhibition and latent inhibition
2. Differential performance of acute and chronic schizophrenics in a latent inhibition task
3. Acute administration of nicotine increases the in vivo extracellular levels of dopamine, 3,4-dihydroyphenylacetic acid and ascorbic acid preferentially in the nucleus accumbens of the rat: comparison with caudate-putamen
4. Blockage of amphetamine-induced motor stimulation and stereotypy in the adult rat following neonatal treatment with 6-hydroxydopamine
5. Effects of antipsychotic drugs on latent inhibition: sensitivity and specificity of an animal behavioural model of clinical drug action
6. The role of mesolimbic and nigrostriatal dopamine in latent inhibition as measured with the conditioned taste aversion paradigm
7. Latent inhibition is unaffected by direct dopamine agonists
8. Integrating schizophrenia
9. The neuropsychology of schizophrenia
10. The role of mesolimbic dopaminergic and retrohippocampal afferents to the nucleus accumbens in latent inhibition: implications for schizophrenia
11. Latent inhibition: the nucleus accumbens connection revisited
12. Abolition of latent inhibition in acute, but not chronic, schizophrenics
13. Abolition of latent inhibition by a single 5mg dose of D-amphetamine in man
14. Latent inhibition in drug naive schizophrenics; relationship to duration of illness and dopamine D2 binding using SPET
15. 6-OHDA lesions of the nucleus accumbens accentuate memory deficits in animals with lesions to the forebrain cholinergic projection system: effects of nicotine administration on learning and memory in the water maze
16. Selective hippocampal lesions abolish the contextual specificity of latent inhibition and conditioning
17. Nicotine preferentially stimulates dopamine release in the limbic system of freely moving rats
18. Nicotine blocks latent inhibition in rats: evidence for a critical role of increased functional activity at conditioning rather than preexpsoure
19. Dopamine transmission in the initiation and expression of drug-and stress-induced sensitisation of motor activity
20. Contextual control of latent inhibition by the reinforcer
21. Diffential effects of intra-accumbens and systemic amphetamine on latent inhibition using an on-baseline, within-subject conditioned suppression paradigm
22. Effects of the neuroleptic α-flupenthixol on latent inhibition in aversively- and appetitively-motivated paradigms: evidence for dopamine-reinforcer interactions
23. Effects of striatal or accumbens lesions on the amphetamine-induced abolition of latent inhibition
24. Effects of D-amphetamine and haloperidol on latent inhibition in healthy male volunteers
25. A single administration of D-amphetamine prior to stimulus pre-exposure and conditioning attenuates latent inhibition
26. Effects of antipsychotics on latent inhibition and eye movements in healthy volunteers
27. Effects of clozapine on latent inhibition in the rat
28. A single amphetamine treatment is able to disrupt latent inhibition in the rat by an action at conditioning alone
29. Systemic nicotine-induced dopamine release in the rat nucleus accumbens is regulated by nicotinic receptors in the ventral tegmental area
30. Haloperidol potentiation of latent inhibition in rats: evidence for a critical role at conditioning rather than pre-exposure
31. Enhancement of latent inhibition in rats with electrolytic lesions of the hippocampus
32. Enduring changes in brain and behaviour produced by chronic amphetamine administration: a review and evaluation of animal models of amphetamine psychosis
33. Effect of nicotine and nicotine receptor agonists on latent inhibition in the rat
34. Differential effects of microinjections of D-amphetamine into the nucleus accumbens or the caudate-putamen on the rat's ability to ignore an irrelevant stimulus
35. Disrupted latent inhibition in the rat with chronic amphetamine or haloperidol-induced supersensitivity: relationship to schizophrenic attention disorder
36. Assesssing the value of an animal model of deficient sensorimotor gating in schizophrenic patients
37. Effects of nicotine and amphetamine on latent inhibition in normal human subjects
38. Latent inhibition and autonomic responses: a psychophysiological approach
39. Amphetamine injected into the ventral tegmental area sensitises the nucleus accumbens dopaminergic response to systemic amphetamine: an in vivo microdialysis study in the rat
40. Antagonism of amphetamine-induced disruption of latent inhibition in rats by haloperidol and ondansetron: implications for a possible antipsychotic action of ondansetron
41. Calcium dependent dopamine release in rat nucleus accumbens following amphetamine challenge: implications for the disruption of latent inhibition
42. Abolition of the expression but not the acquisition of latent inhibition by chronic amphetamine in rats
43. Facilitation of the expression but not the acquisition of latent inhibition by haloperidol in rats
44. Latent inhibition is not affected by acute or chronic administration of 6mg/kg DL-amphetamine
45. Disruption of latent inhibition by acute administration of low doses of amphetamine
46. Basolateral amygdala lesions do not disrupt latent inhibition
47. Social-isolation in the rat produces developmentally specific deficits in prepulse inhibition of the acoustic startle response without disrupting latent inhibition
48. Reduced latent inhibition in people with schizophrenia: an effect of psychosis or its treatment
49. Latent inhibition of conditioned dopamine release in the nucleus accumbens