17β-estradiol inhibits the production of RANTES in human keratinocytes

Journal of Investigative Dermatology

Volumn 120, Issue 3, 2003, Pages 420-427

  Kanda, Naoko ^a   Watanabe, Shinichi ^a  

^a TEIKYO UNIVERSITY   (Japan)

Author keywords

CREB binding protein; Nuclear factor B; Psoriasis

Indexed keywords

CHIMERIC PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; ESTRADIOL; FULVESTRANT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; PROTEIN P50; SYNAPTOTAGMIN; TUMOR NECROSIS FACTOR ALPHA; CREBBP PROTEIN, HUMAN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DNA; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; I KAPPA B; INTERLEUKIN 1; INTERLEUKIN 8; MESSENGER RNA; NUCLEAR PROTEIN; RANTES; TRANSACTIVATOR PROTEIN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL ACTIVITY; CELL STIMULATION; CONTROLLED STUDY; DNA BINDING; DRUG INHIBITION; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; KERATINOCYTE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN SYNTHESIS INHIBITION; BIOSYNTHESIS; CELL CULTURE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SERODIAGNOSIS; TRANSACTIVATION;

CELLS, CULTURED; CREB-BINDING PROTEIN; DNA; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; HUMANS; I-KAPPA B PROTEINS; INTERLEUKIN-1; INTERLEUKIN-8; KERATINOCYTES; NF-KAPPA B; NUCLEAR PROTEINS; PHOSPHORYLATION; PRECIPITIN TESTS; PROMOTER REGIONS (GENETICS); RANTES; RECEPTORS, ESTROGEN; RNA, MESSENGER; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0037337093     PISSN: 0022202X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1523-1747.2003.12067.x     Document Type: Article

References (59)

1. Beato M: Gene regulation by steroid hormones. Cell 56:335-344, 1989
2. Bhat RA, Harnish DC, Stevis PE, Little CR, Komm BS: A novel human estrogen receptor β: identification and functional analysis of additional N-terminal amino acids. J Steroid Biochem Mol Biol 67:233-240, 1998
3. Bos JD, de Rie MA: The pathogenesis of psoriasis: immunological facts and speculations. Immunol Today 20:40-46, 1999
4. Boyd AS, King LE Jr: Tamoxifen-induced remission of psoriasis. J Am Acad Dermatol 41:887-889, 1999
5. Boyd AS, Morris LF, Phillips CM: Psoriasis and pregnancy: hormone and immune system interaction. Int J Dermatol 35:169-172, 1996
6. Cerillo G, Rees A, Manchanda N, Reilly C, Brogan I, White A, Needham M: The oestrogen receptor regulates NFκB and AP-1 activity in a cell-specific manner. J Steroid Biochem Mol Biol 67:79-88, 1998
7. Correale J, Arias M, Gilmore W: Steroid hormone regulation of cytokine secretion by proteolipid protein-specific CD4+ T cell clones isolated from multiple sclerosis patients and normal control subjects. J Immunol 161:3365-3374, 1998
8. Dunna SF, Finlay AV: Psoriasis: improvement during and worsening after pregnancy. Br J Dermatol 120:584, 1989 (Letter)
9. Evans MJ, Eckert A, Lai K, Adelman SJ, Harnish DC: Reciprocal antagonism between estrogen receptor and NF-κB activity in vivo. Circ Res 89:823-830, 2001
10. Evans MJ, Lai K, Shaw LJ, Harnish DC, Chadwick CC: Estrogen receptor α inhibits IL-1β induction of gene expression in the mouse liver. Endocrinology 143:2559-2570, 2002
11. Farber EM, Nall ML: The natural history of psoriasis in 5,600 patients. Dermatologica 148:1-18, 1974
12. 3 (tacalcitol). Br J Dermatol 138:63-70, 1998
13. Galien R, Garcia T: Estrogen receptor impairs interleukin-6 expression by preventing protein binding on the NF-κB site. Nucleic Acids Res 25:2424-2429, 1997
14. Genin P, Algarte M, Roof P, Lin R, Hiscott J: Regulation of RANTES chemokine gene expression requires cooperativity between NF-κB and (FN-regulatory factor transcription factors. J Immunol 164:5352-5361, 2000
15. Gerritsen ME, Williams AJ, Neish AD, Moore S, Shi Y, Collins T: CREB-binding protein/p300 are transcriptional coactivators of p65. Proc Natl Acad Sci USA 94:2927-2932, 1997
16. Gillitzer R, Ritter U, Spandau U, Goebeler M, Brocket E-B: Differential expression of GRO-α and IL-8 mRNA in psoriasis: a model for neutrophil migration and accumulation in vivo. J Invest Dermatol 107:778-782, 1996
17. Gilmore W, Weiner LP, Correale J: Effect of esrradiol on cytokine secretion by proteolipid protein-specific T cell clones isolated from multiple sclerosis patients and normal control subjects. J Immunol 158:446-451, 1997
18. Giustizieri ML, Mascia F, Frezzolini A, et al: Keratinocytes from patients with atopic dermatitis and psoriasis show a distinct chemokine production profile in response to T cell-derived cytokines. J Allergy Clin Immunol 107:871-877, 2001
19. Glass CK, Rosenfeld MG: The coregulator exchange in transcriptional functions of nuclear receptors. Genes Dev 14:121-141, 2000
20. Harnish DC, Scicchitano S, Adelman SJ, Lyttle CR, Karathanasis SK: The role of CBP in estrogen receptor cross-talk with nuclear factor-κB in HepG2 cells. Endocrinology 141:3403-3411, 2000
21. Hornung D, Ryan IP, Chao VA, Vigne J-L, Schriock ED, Taylor RN: Immunolocalization and regulation of the chemokine RANTES in human endometrial and endometriosis tissues and cells. J Clin Endocrinol Metab 82:1621-1628, 1997
22. Hsu S-M, Chen Y-C, Jiang M-C: 17β-estradiol inhibits tumor necrosis factor-α-induced nuclear factor-κB activation by increasing nuclear factor-κB p105 level in MCF-7 breast cancer cells. Biochem Biophys Res Commun 279:47-52. 2000
23. Hu S, Chao CC, Ehrlich LC, Sheng WS, Sutton RL, Rockswold GL, Peterson PK: Inhibition of microglial cell RANTES production by IL-10 and TGF-β. J Leukoc Biol 65:815-821, 1999
24. Kamei Y, Xu L, Heinzel T, et al: A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85:403-414, 1996
25. Kanda N, Watanabe S: 17β-estradiol, protesterone, and dihydrotestosterone suppress the growth of human melanoma by inhibiting interleukin-8 production. J Invest Dermatol 117:274-283, 2001
26. Lin R, Heylbroeck C, Genre P, Pitha PM, Hiscott J: Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription. Mol Cell Biol 19:959-966, 1999
27. Matejuk A, Adlard A, Silverman M, Vandenbark AA, Offner H: 17β-estradiol inhibits cytokine, chemokine, and chemokine receptor mRNA expression mice with experimental autoimmune encephalomuelitis. J Neurosci Res 65:529-542, 2001
28. Matejuk A, Dwyer J, Zamora A, Vandenbark AA, Offner H: Evaluation of the effects of 17β-estradiol (17β-E2) on gene expression in experimental autoimmune encephalomyelitis using DNA microarray. Endocrinology 143:313-319, 2002
29. Mckenna NJ, Lanz RB, O'Malley BW: Nuclear receptor coregulators, cellular and molecular biology. Endocr Rev 20:321-344, 1999
30. McMurray RW, Ndebele K, Hardy KJ, Jenkins JK: 17 β-estradiol suppresses IL-2 and IL-2 receptor. Cytokine 14:324-333, 2001
31. Mendelsohn ME, Karas RH: The protective effects of estrogen on the cardiovascular system. N Engl J Med 340:1801-1811, 1999
32. Moriuchi H, Moriuchi M, Fauci AS: Nuclear factor-κB potently up-regulates the promoter activity of RANTES, a chemokine that blocks HIV infection. J Immunol 158:3483-3491, 1997
33. Mowads CM, Margolis DJ, Halpern AC, Suri B, Synnestvedt M, Guzzo CA: Hormonal influences on women with psoriasis. Cutis 61:257-260, 1998
34. Mukaida N, Morita M, Ishikawa Y, Rice N, Okamoto S, Kasahara T, Matsuchima K: Novel mechanism of glucocorticoid-mediated gene repression. J Biol Chem, 269:13289-13295, 1994
35. Na S-Y, Lee S-K, Han S-J, Choi H-S, Im S-Y, Lee JW: Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor κB-mediated transactivations. J Biol Chem 273:10831-10834, 1998
36. Naumann M, Scheidereit C: Activation of NF-κB in vivo is regulated by multiple phosphorylations. EMBO J 13:4597-4607, 1994
37. Ohmori Y, Tebo J, Nedospasov S, Hamilton TA: κB binding activity in a routine macrophage-like cell line. Sequence-specific diffrences in κB binding and transcriptional activation functions. J Biol Chem 269:17684-17690, 1994
38. Paech K, Webb P, Kuiper GGJM, et al: Differential ligand activation of estrogen receptors ERα and ERβ at AP1 sites. Science 277:1508-1510, 1997
39. Quaedackers ME, van den Brink CE, Wissink S, Schreurs RHMM, Gustafsson J-A, van der Saag PT, van der Burg B: 4-hydroxytamoxifen trans-represses nuclear factor-κB activity in human osteoblastic U2-OS cells through estrogen receptor (EN) α and not through ERβ. Endocrinology 142:1156-1166, 2001
40. Ray P, Ghosh SK, Zhang D-H, Ray A: Repression of interleukin-6 gene expression by 17β-estradiol: inhibition of the DNA-binding activity of the transcription factors NF-IL-6 and NF-κB by the estrogen receptor. FEBS Lett 409:79-85, 1997
41. Raychaudhuri SP, Jiang W-Y, Farber EM, Schall TJ, Ruff MR, Pert CB: Upregulation of RANTES in psoriatic keratinocytes: a possible pathogenic mechanism for psoriasis. Acta Derm Venereol (Stockh) 79:9-11, 1999
42. Schmitz ML, Baeuerle PA: The p65 subunit is responsible for the strong transcription activating potential of NF-κB. EMBO J 10:3805-3817, 1991
43. Schrunr S, Probst P, Fleischer B, Zipfel PF: Synthesis of the CC-chemokines MIP-10α, MIP-1β, and RANTES is associated with a type 1 immune response. J Immunol 157:3598-3604, 1996
44. Sheppard K-A, Rose DW, Haqne ZK, et al: Transcriptional activation by NF-κB requires multiple coactivators. Mol Cell Biol 19:6367-6378, 1999
45. Simoncini T, Maffei S, Basta G, Barsacehi G, Genazzani AR, Liao JK, de Caterina R: Estrogens and glucocorticoids inhibit endothelial vascular cell adhesion molecule-1 expression by different transcriptional mechanisms. Circ Res 87:19-25, 2000
46. Siveke JT, Hamann A: T helper I and T helper 2 cells respond differentially to chemokines. J Immunol 160:550-554, 1998
47. Speir E, Yu Z-X, Takeda K, Ferrans VJ, Cannon RO: Competition for p300 regulates transcription by estrogen receptors and nuclear factor-κB in human coronary smooth muscle cells. Circ Res 87:1006-1011, 2000
48. Stein B, Yang MX: Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-κB and C/EBPβ Mol Cell Biol 15:4971-4979, 1995
49. Stein B, Baldwin AS Jr, Ballard DW, Greene WC, Angel P, Herrlich P: Cross-coupling of the NF-κB p63 and Fos/June transcription factors produces potentiated biological function. EMBO J 12:3879-3891, 1993
50. Stellato C, Beck LA, Gorgone GA, et al: Expression of the chemokine RANTES by a human bronchial epithelial cell line. Modulation by cytokines and glucocorticoids. J Immunol 155:410-418, 1995
51. Stevens HP, Ostlere LS, Black CM, Jacobs HS, Rustin MHA: Cyclical psoriatic arthritis responding to anti-oestrogen therapy. Br J Dermatol 129:458-460, 1993
52. Sun WH, Keller ET, Stebler BS, Ershler WB: Estrogen inhibits phorbol ester-induced IκBα transcription and protein degradation Bioehem Biophys Res Commun 244:691-695, 1998
53. 2 in human prostatic carcinoma cells. Br J Cancer 75:1111-1118, 1997
54. Torchia J, Glass C, Rosenfeld M: Co-activators and co-repressors in the integration of transcriptional responses. Curr Opin Cell Biol 10:373-383, 1998
55. Uyemura K, Yamamura M, Fivenson DF, Modlin RL, Nickloff BJ:The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helper type 1 cell-mediated response. J Invest Dermatol 101:701-705, 1993
56. Valentine JE, Kalkhoven E, White R, Hoare S, Parker MG: Mutations in the estrogen receptor ligand binding domain discriminate between hormone-dependent transactivation and transrepression. J Biol Chem 275:25322-25329, 2000
57. Wood GW, Hausmann E, Choudhuri N: Relative role of CSF-1, MCP-1/JE, and RANTES in macrophage recruitment during successful pregnancy. Mol Reprod Dev 46:62-70, 1997
58. Ying S, Taborda-Barata L, Meng Q, Humbert M, Kay AB: The kinetics of-allergen-induced transcription of messenger RNA for monocyte chemotactic protein-3 and RANTES in the skin of human atopic subjects: relationship to eosmophil, T cell, and macrophage recruitment. J Exp Med 181:2153-2159, 1995
59. Zellmer S, Gaunitz F, Salvetter J, Surovoy A, Reissig D, Gebhardt R: Long-term expression of foreign genes in normal human epidermal keratinocytes after transfection with lipid/DNA complexes. Histochem Cell Biol 115:41-47, 2001