Structure-activity relationships of xanthene carboxamides, novel CCR1 receptor antagonists

Bioorganic and Medicinal Chemistry

Volumn 11, Issue 6, 2003, Pages 875-884

  Naya, Akira ^a   Ishikawa, Makoto ^a   Matsuda, Kenji ^a   Ohwaki, Kenji ^a   Saeki, Toshihiko ^a   Noguchi, Kazuhito ^a   Ohtake, Norikazu ^a  

^a TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 [[(3 AMINOMETHYL)PIPERIDINO]CARBONYL] N [1 (1 CYCLONONENYLMETHYL)PIPERIDIN 4 YL]XANTHEN 9 CARBOXAMIDE; AMIDE; CHEMOKINE RECEPTOR CCR1; QUATERNARIZED XANTHEN 9 CARBOXAMIDE; UNCLASSIFIED DRUG; XANTHEN 9 CARBOXAMIDE LEAD;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING ASSAY; CHINESE HAMSTER; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; GENETIC TRANSFECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; MONOCYTE; NONHUMAN; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

AMIDES; ANIMALS; CALCIUM; CHO CELLS; CRICETINAE; DOGS; HUMANS; INDICATORS AND REAGENTS; MAGNETIC RESONANCE SPECTROSCOPY; MICROSOMES, LIVER; RATS; RECEPTORS, CHEMOKINE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; U937 CELLS; XANTHENES;

EID: 0037333865     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(02)00559-X     Document Type: Article

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