-
1
-
-
0031544690
-
Intestinal cell models: Their use in evaluating the metabolism and absorption of xenobiotics
-
X. Boulenc. Intestinal cell models: Their use in evaluating the metabolism and absorption of xenobiotics. S. T. P. Pharm. Sci. 7:259-269 (1997).
-
(1997)
S. T. P. Pharm. Sci.
, vol.7
, pp. 259-269
-
-
Boulenc, X.1
-
2
-
-
0021067619
-
Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture
-
M. Pinto, S. Robine-Leon, M. D. Appay, M. Kedinger, N. Triadou, E. Dussaulx, B. Lacroix, P. Simon-Assmann, K. Haffen, J. Fogh, and A. Zweibaum. Enterocyte-like differentiation and polarization of the human colon carcinoma cell line Caco-2 in culture. Biol. Cell 47:323-330 (1983).
-
(1983)
Biol. Cell
, vol.47
, pp. 323-330
-
-
Pinto, M.1
Robine-Leon, S.2
Appay, M.D.3
Kedinger, M.4
Triadou, N.5
Dussaulx, E.6
Lacroix, B.7
Simon-Assmann, P.8
Haffen, K.9
Fogh, J.10
Zweibaum, A.11
-
3
-
-
0030588585
-
Carrier-mediated transport and efflux mechanisms in Caco-2 cells
-
I. J. Hidalgo and J. Li. Carrier-mediated transport and efflux mechanisms in Caco-2 cells. Adv. Drug Delivery Rev. 22:53-66 (1996).
-
(1996)
Adv. Drug Delivery Rev.
, vol.22
, pp. 53-66
-
-
Hidalgo, I.J.1
Li, J.2
-
4
-
-
0031413702
-
Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond
-
P. Artursson and R. T. Borchardt. Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond. Pharm. Res. 14:1655-1658 (1997).
-
(1997)
Pharm. Res.
, vol.14
, pp. 1655-1658
-
-
Artursson, P.1
Borchardt, R.T.2
-
5
-
-
0342762062
-
The barrier function of CYP3A4 and P-glycoprotein in the small bowel
-
P. B. Watkins. The barrier function of CYP3A4 and P-glycoprotein in the small bowel. Adv. Drug Deliv. Rev. 27:161-170 (1997).
-
(1997)
Adv. Drug Deliv. Rev.
, vol.27
, pp. 161-170
-
-
Watkins, P.B.1
-
6
-
-
0032406596
-
Conditionally immortalized intestinal epithelial cells
-
V. Milovic, G. Ocklind, and P. Artursson. Conditionally immortalized intestinal epithelial cells. Ann. NY Acad. Sci. 859:201-203 (1998).
-
(1998)
Ann. NY Acad. Sci.
, vol.859
, pp. 201-203
-
-
Milovic, V.1
Ocklind, G.2
Artursson, P.3
-
7
-
-
0035478419
-
The drug effiux-metabolism alliance: Biochemical aspects
-
L. Z. Benet and C. L. Cummins. The drug effiux-metabolism alliance: Biochemical aspects. Adv. Drug Deliv. Rev. 50:S3-S11 (2001).
-
(2001)
Adv. Drug Deliv. Rev.
, vol.50
-
-
Benet, L.Z.1
Cummins, C.L.2
-
8
-
-
0033985306
-
Function and expression of multidrug resistance-associated protein family in human colon adenocarcinoma cells (Caco-2)
-
T. Hirohashi, H. Suzuki, X.-Y. Chu, I. Tamai, A. Tsuji, and Y. Sugiyama. Function and expression of multidrug resistance-associated protein family in human colon adenocarcinoma cells (Caco-2). J. Pharmacol. Exp. Ther. 292:265-270 (2000).
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.292
, pp. 265-270
-
-
Hirohashi, T.1
Suzuki, H.2
Chu, X.-Y.3
Tamai, I.4
Tsuji, A.5
Sugiyama, Y.6
-
9
-
-
0030945754
-
Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1α,25-dihydroxyvitamin D 3
-
P. Schmiedlin-Ren, K. E. Thummel, J. M. Fisher, M. F. Paine, K. S. Lown, and P. B. Watkins. Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1α,25-dihydroxyvitamin D3. Mol. Pharmacol. 51:741-754 (1997).
-
(1997)
Mol. Pharmacol.
, vol.51
, pp. 741-754
-
-
Schmiedlin-Ren, P.1
Thummel, K.E.2
Fisher, J.M.3
Paine, M.F.4
Lown, K.S.5
Watkins, P.B.6
-
10
-
-
0034807802
-
Characterizing the expression of CYP3A4 and effiux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-otetradecanoylphorbol-13-acetate
-
C. L. Cummins, L. M. Mangravite, and L. Z. Benet. Characterizing the expression of CYP3A4 and effiux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-otetradecanoylphorbol-13-acetate. Pharm. Res. 18:1102-1109 (2001).
-
(2001)
Pharm. Res.
, vol.18
, pp. 1102-1109
-
-
Cummins, C.L.1
Mangravite, L.M.2
Benet, L.Z.3
-
11
-
-
0035152853
-
CYP3A4, CYP3A 5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies
-
H. A. Engman, H. Lennernäs, J. Taipalensuu, C. Otter, B. Leidvik, and P. Artursson. CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies. J. Pharm. Sci. 90:1736-1751 (2001).
-
(2001)
J. Pharm. Sci.
, vol.90
, pp. 1736-1751
-
-
Engman, H.A.1
Lennernäs, H.2
Taipalensuu, J.3
Otter, C.4
Leidvik, B.5
Artursson, P.6
-
12
-
-
18244390013
-
Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cell lines, human duodenal enterocytes, normal colorectal tissues and colorectal adenocarcinomas
-
T. Nakamura, T. Sakaeda, N. Ohmoto, T. Tamura, N. Aoyama, T. Shirakawa, T. Kamigaki, T. Nakamura, K. I. Kim, S. R. Kim, Y. Kuroda, M. Matsuo, M. Kasuga, and K. Okumura. Real-time quantitative polymerase chain reaction for MDR1, MRP1, MRP2, and CYP3A-mRNA levels in Caco-2 cell lines, human duodenal enterocytes, normal colorectal tissues and colorectal adenocarcinomas. Drug Metab. Dispos. 30:4-6 (2002).
-
(2002)
Drug Metab. Dispos.
, vol.30
, pp. 4-6
-
-
Nakamura, T.1
Sakaeda, T.2
Ohmoto, N.3
Tamura, T.4
Aoyama, N.5
Shirakawa, T.6
Kamigaki, T.7
Nakamura, T.8
Kim, K.I.9
Kim, S.R.10
Kuroda, Y.11
Matsuo, M.12
Kasuga, M.13
Okumura, K.14
-
13
-
-
12644272784
-
Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine
-
K. S. Lown, R. R. Mayo, A. B. Leichtman, H. L. Hsiao, D. K. Turgeon, P. Schmiedlin-Ren, M. B. Brown, W. Guo, S. J. Rossi, L. Z. Benet, and P. B. Watkins. Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine. Clin. Pharmacol. Ther. 62:248-260 (1997).
-
(1997)
Clin. Pharmacol. Ther.
, vol.62
, pp. 248-260
-
-
Lown, K.S.1
Mayo, R.R.2
Leichtman, A.B.3
Hsiao, H.L.4
Turgeon, D.K.5
Schmiedlin-Ren, P.6
Brown, M.B.7
Guo, W.8
Rossi, S.J.9
Benet, L.Z.10
Watkins, P.B.11
-
14
-
-
0033958086
-
Multiple physiological functions for multidrug transporter P-glycoprotein
-
R. W. Johnstone, A. A. Ruefli, and M. J. Smyth. Multiple physiological functions for multidrug transporter P-glycoprotein. Trends Biochem. Sci. 25:1-6 (2000).
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 1-6
-
-
Johnstone, R.W.1
Ruefli, A.A.2
Smyth, M.J.3
-
15
-
-
0035286778
-
Caco-2 monolayers in experimental and theoretical predictions of drug transport
-
P. Artursson, K. Palm, and K. Luthman. Caco-2 monolayers in experimental and theoretical predictions of drug transport. Adv. Drug Deliv. Rev. 46:27-43 (2001).
-
(2001)
Adv. Drug Deliv. Rev.
, vol.46
, pp. 27-43
-
-
Artursson, P.1
Palm, K.2
Luthman, K.3
|