The protein tyrosine phosphatase HePTP regulates nuclear translocation of ERK2 and can modulate megakaryocytic differentiation of K562 cells

Leukemia

Volumn 17, Issue 2, 2003, Pages 366-378

  Pettiford, S M ^a   Herbst, R ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Cellular differentiation; Oncogene; Protein phosphatase

Indexed keywords

CELL MARKER; COMPLEMENTARY DNA; CYCLIN D; FIBRINOGEN RECEPTOR; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN TYROSINE PHOSPHATASE;

ARTICLE; CELL CYCLE; CELL DIFFERENTIATION; CELL STRAIN K 562; CELL STRUCTURE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE OVEREXPRESSION; GENE TRANSLOCATION; HEMATOPOIETIC SYSTEM TUMOR; HUMAN; HUMAN CELL; MEGAKARYOCYTE; MYELOID LEUKEMIA; PRIORITY JOURNAL; UPREGULATION;

EID: 0037330623     PISSN: 08876924     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.leu.2402767     Document Type: Article

References (38)

1. Cobb MH, Goldsmith EJ. How MAP kinases are regulated. J Biol Chem 1995; 270: 14843-14846.
2. Lewis TS, Shapiro PS, Ahn NG. Signal transduction through MAP kinase cascades. Adv Cancer Res 1998; 65: 49-139.
3. Garrington TP, Johnson GL. Organization and regulation of mitogen-activated protein kinase signaling pathways. Curr Opin Cell Biol 1999; 11: 211-218.
4. Treisman R. Regulation of transcription by MAP kinase cascades. Curr Opin Cell Biol 1996; 8: 205-215.
5. Cobb MH, Goldsmith EJ. Dimerization in MAP-kinase signaling. Trends Biol Sci 2000; 25: 7-9.
6. Whalen AM, Galasinski SC, Shapiro PS, Stines Nahreini T, Ahn NG. Megakaryocytic differentiation induced by constitutive activation of mitogen-activated protein kinase kinase. Mol Cell Biol 1997; 17: 1947-1958.
7. Racke FK, Lewandowska K, Goueli S, Goldfarb AN. Sustained activation of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway is required for megakaryocytic differentiation of K562 cells. J Biol Chem 1997; 272: 23366-23370.
8. Shelly C, Petruzzelli L, Herrera R. PMA-induced phenotypic changes in K562 cells: MAPK-dependent and-independent events. Leukemia 1998; 12: 1951-1961.
9. Kang C-D, Do I-R, Kim K-W, Ahn B-K, Kim S-H, Chung B-S, Jhun B-H, Yoo M. Role of Ras/ERK-dependent pathway in erythroid differentiation of K562 cells. Exp Mol Med 1999; 31: 76-82.
10. Keyse SM. Protein phosphatases and the regulation of mitogen-activated protein kinase signaling. Curr Opin Cell Biol 2000; 12: 186-192.
11. Saxena M, Williams S, Brockdorff J, Gilman J, Mustelin T. Inhibition of T cell signaling by mitogen-activated protein kinase-targeted hematopoietic tyrosine phosphatase (HePTP). J Biol Chem 1999; 274: 11693-11700.
12. Oh-hora M, Ogata M, Mori Y, Adachi M, Imai K, Kosugi A, Hamaoka T. Direct suppression of TCR-mediated activation of extracellular signal-regulated kinase by leukocyte protein tyrosine phosphatase, a tyrosine-specific phosphatase. J Immunol 1999; 163: 1282-1288.
13. Pettiford SM, Herbst R. The MAP-kinase ERK2 is a specific substrate of the protein tyrosine phosphatase HePTP. Oncogene 2000; 19: 856-869.
14. Saxena M, Williams S, Gilman J, Mustelin T. Negative regulation of T cell antigen receptor signal transduction by hematopoietic tyrosine phosphatase (HePTP). J Biol Chem 1998; 273: 15340-15344.
15. Pulido R, Zu'niga A, Ullrich A. PTP-SL and STEP protein tyrosine phosphatases regulate the activation of the extracellular signal-regulated kinases ERK1 and ERK2 by association through a kinase interaction motif. EMBO J 1998; 17: 7337-7350.
16. Adachi M, Sekiya M, Isobe M, Kumura Y, Ogita Z-I, Hinoda Y, Imai K, Yachi A. Molecular cloning and chromosomal mapping of a human protein-tyrosine phosphatase LC-PTP. Biochem Biophys Res Commun 1992; 186: 1607-1615.
17. Zanke B, Suzuki H, Kishihara K, Minden M, Pawson A, Mak TW. Cloning and expression of an inducible lymphoid-specific, protein tyrosine phosphatase (HePTPase). Eur J Immunol 1992; 22: 235-239.
18. Lombroso PJ, Murdoch G, Lerner M. Molecular characterization of a protein-tyrosine-phosphatase enriched in striatum. Proc Natl Acad Sci USA 1991; 88: 7242-7246.
19. Hendriks W, Schepens J, Burgman C, Zeeuwen P, Wieringa B. A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain. Biochem J 1995; 305: 499-504.
20. Zuniga A, Torres J, Ubeda J, Pulido R. Interaction of mitogen-activated protein kinases with the kinase interaction motif of the tyrosine phosphatase PTP-SL provides substrate specificity and retains ERK2 in the cytoplasm. J Biol Chem 1999; 274: 21900-21907.
21. Saxena M, Williams S, Tasken K, Mustelin T. Crosstalk between cAMP-dependent kinase and MAP kinase through a protein tyrosine phosphatase. Nature Cell Biol 1999; 1: 305-311.
22. Blanco-Aparicio C, Torres J, Pulido R. A novel mechanism of MAP kinase activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase. J Cell Biol 1999; 147: 1129-1135
23. Lee CH, Yun HJ, Kang HS, Kim HD. ERK/MAPK pathway is required for changes of cyclin D1 and B1 during phorbol 12-myristate 13-acetate-induced differentiation of K562 cells. Life 1999; 48: 585-591.
24. Ku H, Meier KE. Phosphorylation of paxillin via the ERK mitogen-activated protein kinase cascade in EL4 thymoma cells. J Biol Chem 2000; 275: 11333-11340.
25. Herrera R, Hubbell S, Decker S, Petruzzelli L. A role for the MEK/MAPK pathway in PMA-induced cell cycle arrest: modulation of megakaryocytic differentiation of K562 cells. Exp Cell Res 1998; 238: 407-414.
26. Williams MJ, Du X, Loftus JC, Ginsberg MH. Platelet adhesion receptors. Semin Cell Biol 1995; 6: 305-314.
27. Navarro S, Mitjavila MT, Katz A, Doly J, Vainchenker W. Expression of interleukin 6 and its specific receptor by untreated and PMA-stimulated human erythroid and megakaryocytic cell lines. Exp Hematol 1991; 19: 11-17.
28. Xie P, Chan FSL, Ip NY, Leung M-F. Induction of gp130 and LIF by differentiation inducers in human myeloid leukemia K562 cells. Leukemia Res 1999; 23: 1113-1119.
29. Butler TM, Ziemiecki A, Friis RR. Megakaryocytic differentiation of K562 cells is associated with changes in the cytoskeletal organization and the pattern of chromatographically distinct forms of phosphotyrosyl-specific protein phosphatases. Cancer Res 1990; 50: 6323-6329.
30. Uchida M, Kirito K, Shimizu R, Miura Y, Ozawa K, Komatsu N. A functional role of mitogen-activated protein kinases, erk1 and erk2, in the differentiation of a human leukemia cell line, UT7/GM: a possible key factor for cell fate determination towards erythroid and megakaryocytic lineages. Int J Hematol 2001; 73: 78-83.
31. Witt O, Sand K, Pekrun A. Butyrate-induced erythroid differentiation of human K562 leukemia cells involves inhibition of ERK and activation of p38 MAP kinase pathways. Blood 2000; 95: 2391-2396.
32. Miyazaki R, Ogata H, Kobayashi Y. Requirement of thrombopoietin-induced activation of ERK for megakaryocyte differentiation and of p38 for erythroid differentiation. Ann Hematol 2001; 80: 284-291.
33. Woessmann W, Mivechi NF. Role of ERK activation in growth and erythroid differentiation of K562 cells. Exp Cell Res 2002; 264: 193-200.
34. Rivero JA, Adunyan SE. Sodium butyrate induces tyrosine phosphorylation and activation of MAP kinase (ERK-1) in human K562 cells. Biochem Biophys Res Commun 1996; 224: 796-801.
35. Gronda M, Arab S, Iafrate B, Suzuki H, Zanke BW. Hematopoietic protein tyrosine phosphatase suppresses extracellular stimulus-regulated kinase activation. Mol Cell Biol 2001; 21: 6851-6858.
36. Cheng A, Bal GS, Kennedy BP, Tremblay ML. Attenuation of adhesion-dependent signaling and cell spreading in transformed fibroblast lacking protein tyrosine phosphatase-1B. J Biol Chem 2001; 276: 25848-25855.
37. Zanke B, Squire J, Griesser H, Henry M, Suzuki H, Patterson B, Minden M, Mak TW. A hematopoietic protein tyrosine phosphatase (HePTP) gene that is amplified and overexpressed in myeloid malignancies maps to chromosome 1q32.1. Leukemia 1994; 8: 236-244.
38. Mitelman F, Kaneko Y, Trent J. Report of the committee on chromosome changes in neoplasia. Cytogenet Cell Genet 1990; 55: 358-386.